| MeSH term | MeSH ID | Detail |
|---|---|---|
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
| Mitochondrial Diseases | D028361 | 25 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fernandez-Gomez FJ et al. | Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. | 2005 | Neuroscience | pmid:15964487 |
| Wang J et al. | Coexistence of two bifurcation regimes in a closed ferroin-catalyzed Belousov-Zhabotinsky reaction. | 2005 | J Phys Chem A | pmid:16833454 |
| Kitahata H et al. | Propagation of photosensitive chemical waves on the circular routes. | 2005 | J Phys Chem A | pmid:16833846 |
| Belgorodsky B et al. | Formation and characterization of stable human serum albumin-tris-malonic acid [C60]fullerene complex. | 2005 Sep-Oct | Bioconjug. Chem. | pmid:16173780 |
| Fedotcheva NI et al. | Nonezymatic formation of succinate in mitochondria under oxidative stress. | 2006 | Free Radic. Biol. Med. | pmid:16781453 |
| Zhang X et al. | Degradation of 17alpha-ethinylestradiol in aqueous solution by ozonation. | 2006 | J. Hazard. Mater. | pmid:16387433 |
| Fondo M et al. | Dinuclear Co(III)/Co(III) and Co(II)/Co(III) mixed-valent complexes: synthetic control of the cobalt oxidation level. | 2006 | Dalton Trans | pmid:17047739 |
| Bonsi P et al. | Mitochondrial toxins in Basal Ganglia disorders: from animal models to therapeutic strategies. | 2006 | Curr Neuropharmacol | pmid:18615133 |
| Bulluss GH et al. | trans-Platinum planar amine compounds with [N2O2] ligand donor sets: effects of carboxylate leaving groups and steric hindrance on chemical and biological properties. | 2006 | Inorg Chem | pmid:16841974 |
| Kulp DC and Jagalur M | Causal inference of regulator-target pairs by gene mapping of expression phenotypes. | 2006 | BMC Genomics | pmid:16719927 |
| Tillman AL et al. | Direct enantio- and diastereoselective Mannich reactions of malonate and beta-keto esters with N-Boc and N-Cbz aldimines catalysed by a bifunctional cinchonine derivative. | 2006 | Chem. Commun. (Camb.) | pmid:16518487 |
| Drewes SE et al. | Antimicrobial monomeric and dimeric diterpenes from the leaves of Helichrysum tenax var tenax. | 2006 | Phytochemistry | pmid:16434071 |
| Josyula AB et al. | Reduction in urinary arsenic with bottled-water intervention. | 2006 | J Health Popul Nutr | pmid:17366771 |
| Levinson NM et al. | A Src-like inactive conformation in the abl tyrosine kinase domain. | 2006 | PLoS Biol. | pmid:16640460 |
| Tang GL et al. | Polyketide chain skipping mechanism in the biosynthesis of the hybrid nonribosomal peptide-polyketide antitumor antibiotic leinamycin in Streptomyces atroolivaceus S-140. | 2006 | J. Nat. Prod. | pmid:16562841 |
| Li S and Li XJ | Multiple pathways contribute to the pathogenesis of Huntington disease. | 2006 | Mol Neurodegener | pmid:17173700 |
| Suedee R et al. | The use of trichloroacetic acid imprinted polymer coated quartz crystal microbalance as a screening method for determination of haloacetic acids in drinking water. | 2006 | Talanta | pmid:18970752 |
| Licht TR et al. | Dietary carbohydrate source influences molecular fingerprints of the rat faecal microbiota. | 2006 | BMC Microbiol. | pmid:17137493 |
| Romualdi C et al. | Defining the gene expression signature of rhabdomyosarcoma by meta-analysis. | 2006 | BMC Genomics | pmid:17090319 |
| Huang QY et al. | Adenosine A2A receptors in bone marrow-derived cells but not in forebrain neurons are important contributors to 3-nitropropionic acid-induced striatal damage as revealed by cell-type-selective inactivation. | 2006 | J. Neurosci. | pmid:17079665 |
| Yun YS et al. | Arg-158 is critical in both binding the substrate and stabilizing the transition-state oxyanion for the enzymatic reaction of malonamidase E2. | 2006 | J. Biol. Chem. | pmid:17077089 |
| Iversen C et al. | The biochemical differentiation of Enterobacter sakazakii genotypes. | 2006 | BMC Microbiol. | pmid:17067387 |
| Yennawar NH et al. | Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. | 2006 | J. Biol. Chem. | pmid:17050531 |
| Tang L et al. | Inferring direct regulatory targets from expression and genome location analyses: a comparison of transcription factor deletion and overexpression. | 2006 | BMC Genomics | pmid:16923194 |
| Wang X et al. | Analysis of substrate-binding elements in OxlT, the oxalate:formate antiporter of Oxalobacter formigenes. | 2006 | Biochemistry | pmid:16922510 |
| Jackson CJ et al. | The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes. | 2006 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:16820687 |
| Arthur CJ et al. | The malonyl transferase activity of type II polyketide synthase acyl carrier proteins. | 2006 | Chem. Biol. | pmid:16793516 |
| Tamaya K et al. | Interpretation of solute retention of some monovalent inorganic anions in anion-exchange chromatography using a dicarboxylic Acid as an eluent. | 2006 | Anal Sci | pmid:16770050 |
| Oh SJ et al. | Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks. | 2006 | BMC Bioinformatics | pmid:16753070 |
| Tsao R et al. | Isoflavone profiles of red clovers and their distribution in different parts harvested at different growing stages. | 2006 | J. Agric. Food Chem. | pmid:16881680 |
| Zhang Y et al. | Phylophenetic properties of metabolic pathway topologies as revealed by global analysis. | 2006 | BMC Bioinformatics | pmid:16684350 |
| Sprague ER et al. | Crystal structure of the HSV-1 Fc receptor bound to Fc reveals a mechanism for antibody bipolar bridging. | 2006 | PLoS Biol. | pmid:16646632 |
| Playsted CW et al. | Functional significance of dauciform roots: exudation of carboxylates and acid phosphatase under phosphorus deficiency in Caustis blakei (Cyperaceae). | 2006 | New Phytol. | pmid:16626471 |
| Matot I et al. | A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion. | 2006 | Crit Care | pmid:16623960 |
| Leshkowitz D et al. | Whitefly (Bemisia tabaci) genome project: analysis of sequenced clones from egg, instar, and adult (viruliferous and non-viruliferous) cDNA libraries. | 2006 | BMC Genomics | pmid:16608516 |
| Devereux M et al. | Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine). | 2006 | Bioinorg Chem Appl | pmid:17497019 |
| Lash LH | Mitochondrial glutathione transport: physiological, pathological and toxicological implications. | 2006 | Chem. Biol. Interact. | pmid:16600197 |
| Di Noia MA et al. | Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes. | 2006 | J. Biol. Chem. | pmid:16595661 |
| Goldfuss B et al. | A superior P-H phosphonite: asymmetric allylic substitutions with fenchol-based palladium catalysts. | 2006 | Beilstein J Org Chem | pmid:16573833 |
| Li CM et al. | Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21. | 2006 | BMC Med. Genet. | pmid:16539728 |
| van Schöll L et al. | Organic anion exudation by ectomycorrhizal fungi and Pinus sylvestris in response to nutrient deficiencies. | 2006 | New Phytol. | pmid:16539612 |
| Saft C et al. | Dose-dependent improvement of myoclonic hyperkinesia due to Valproic acid in eight Huntington's Disease patients: a case series. | 2006 | BMC Neurol | pmid:16507108 |
| Maklashina E et al. | Fumarate reductase and succinate oxidase activity of Escherichia coli complex II homologs are perturbed differently by mutation of the flavin binding domain. | 2006 | J. Biol. Chem. | pmid:16484232 |
| Dunning Hotopp JC et al. | Comparative genomics of emerging human ehrlichiosis agents. | 2006 | PLoS Genet. | pmid:16482227 |
| Issabayeva G et al. | Removal of lead from aqueous solutions on palm shell activated carbon. | 2006 | Bioresour. Technol. | pmid:16321520 |
| Carmona-Saez P et al. | Integrated analysis of gene expression by Association Rules Discovery. | 2006 | BMC Bioinformatics | pmid:16464256 |
| Wilson JW and Nickerson CA | A new experimental approach for studying bacterial genomic island evolution identifies island genes with bacterial host-specific expression patterns. | 2006 | BMC Evol. Biol. | pmid:16396675 |
| Huang LS et al. | 3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. | 2006 | J. Biol. Chem. | pmid:16371358 |
| Zhao Z et al. | A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis. | 2006 | BMC Neurosci | pmid:16584562 |
| Xu F et al. | Modulation of expression of rat mitochondrial 2-oxoglutarate carrier in NRK-52E cells alters mitochondrial transport and accumulation of glutathione and susceptibility to chemically induced apoptosis. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16291728 |
| Pajor AM | Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters. | 2006 | Pflugers Arch. | pmid:16211368 |
| Horváth K and Hajós P | Retention profiles and mechanism of anion separation on latex-based pellicular ion exchanger in ion chromatography. | 2006 | J Chromatogr A | pmid:16337639 |
| Klivenyi P et al. | Mice lacking alpha-synuclein are resistant to mitochondrial toxins. | 2006 | Neurobiol. Dis. | pmid:16298531 |
| Knauf F et al. | The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates. | 2006 | Biochem. J. | pmid:16608441 |
| de Lago E et al. | UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. | 2006 | Eur Neuropsychopharmacol | pmid:16006105 |
| Guo ML and Cao HX | Poly[tetra-mu-aqua-hexaaquadi-mu3-malonato-dinitratodibarium(II)nickel(II)]. | 2006 | Acta Crystallogr C | pmid:16954628 |
| Aliverdieva DA et al. | Specific features of changes in levels of endogenous respiration substrates in Saccharomyces cerevisiae cells at low temperature. | 2006 | Biochemistry Mosc. | pmid:16457616 |
| MÃguez DG et al. | Effect of axial growth on Turing pattern formation. | 2006 | Phys. Rev. Lett. | pmid:16486904 |
| Delgado FS et al. | Malonate-containing manganese(III) complexes: synthesis, crystal structure, and magnetic properties of AsPh4[Mn(mal)2(H2O)2]. | 2006 | Inorg Chem | pmid:16441108 |
| Ma J et al. | Fenton degradation of organic pollutants in the presence of low-molecular-weight organic acids: cooperative effect of quinone and visible light. | 2006 | Environ. Sci. Technol. | pmid:16468411 |
| Goñi-Allo B et al. | Studies on striatal neurotoxicity caused by the 3,4-methylenedioxymethamphetamine/ malonate combination: implications for serotonin/dopamine interactions. | 2006 | J. Psychopharmacol. (Oxford) | pmid:16510482 |
| Kim HI et al. | Cluster phase chemistry: gas-phase reactions of anionic sodium salts of dicarboxylic acid clusters with water molecules. | 2006 | J Phys Chem A | pmid:16789762 |
| Hayat S et al. | Serotonin transporter expression is not sufficient to confer cytotoxicity to 3,4-methylenedioxymethamphetamine (MDMA) in vitro. | 2006 | J. Psychopharmacol. (Oxford) | pmid:16510483 |
| Wenzel SC et al. | On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A. | 2006 | J. Am. Chem. Soc. | pmid:17076505 |
| Manz N and Steinbock O | Propagation failures, breathing pulses, and backfiring in an excitable reaction-diffusion system. | 2006 | Chaos | pmid:17014246 |
| Hegedüs L et al. | Contribution to the chemistry of the Belousov-Zhabotinsky reaction. Products of the Ferriin-Bromomalonic acid and the Ferriin-Malonic acid reactions. | 2006 | J Phys Chem A | pmid:17125298 |
| Ma Y et al. | Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase. | 2006 | Chembiochem | pmid:17086560 |
| MÃguez DG et al. | Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction. | 2006 | Phys. Rev. Lett. | pmid:17155511 |
| Sasamoto N et al. | Pd(II)-catalyzed asymmetric addition of malonates to dihydroisoquinolines. | 2006 | J. Am. Chem. Soc. | pmid:17061867 |
| Janssen AJ et al. | Measurement of the energy-generating capacity of human muscle mitochondria: diagnostic procedure and application to human pathology. | 2006 | Clin. Chem. | pmid:16543390 |
| Zhang YM et al. | Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae. | 2006 | J. Biol. Chem. | pmid:16618705 |
| Saad LO et al. | Lactate dehydrogenase activity is inhibited by methylmalonate in vitro. | 2006 | Neurochem. Res. | pmid:16758363 |
| Holyoak T et al. | Structural insights into the mechanism of PEPCK catalysis. | 2006 | Biochemistry | pmid:16819824 |
| Zhao B et al. | Ligand-assisted inhibition in cytochrome P450 158A2 from Streptomyces coelicolor A3(2). | 2006 | Biochemistry | pmid:16768445 |
| Trask AV et al. | Physical stability enhancement of theophylline via cocrystallization. | 2006 | Int J Pharm | pmid:16769188 |
| Cuthill DJ et al. | Different patterns of axonal damage after intracerebral injection of malonate or AMPA. | 2006 | Exp. Neurol. | pmid:16698016 |
| Batandier C et al. | The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin. | 2006 | J. Bioenerg. Biomembr. | pmid:16732470 |
| Xu R et al. | Effect of low molecular weight organic acids on adsorption and desorption of fluoride on variable charge soils. | 2006 Feb-Apr | Environ Geochem Health | pmid:16528583 |
| Huang LS et al. | Crystallographic studies of the binding of ligands to the dicarboxylate site of Complex II, and the identity of the ligand in the "oxaloacetate-inhibited" state. | 2006 Sep-Oct | Biochim. Biophys. Acta | pmid:16935256 |
| Pizzuto R et al. | Is there a pyruvate kinase in pig liver mitochondria? | 2007 | Ital. J. Biochem. | pmid:19192625 |
| Ruangpornvisuti V and Wanno B | Molecular model for host–guest interaction of tetraamino-tert-butylthiacalix[4]arene and tetraamino-tert-butylcalix[4]arene receptors with carboxylate and dicarboxylate guests: an ONIOM study. | 2007 | J Mol Model | pmid:16738872 |
| Bakry R et al. | Medicinal applications of fullerenes. | 2007 | Int J Nanomedicine | pmid:18203430 |
| Creaven BS et al. | Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2].8.8H(2)O and [Cu(4-Mecdoa)(phen)2].13H2O (phen=1,10-phenanthroline). | 2007 | J. Inorg. Biochem. | pmid:17555821 |
| Mailloux RJ et al. | The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. | 2007 | PLoS ONE | pmid:17668068 |
| Lovell TM et al. | Identification of a novel mammalian post-translational modification, phosphocholine, on placental secretory polypeptides. | 2007 | J. Mol. Endocrinol. | pmid:17766644 |
| Vindal V et al. | GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. | 2007 | BMC Genomics | pmid:17714599 |
| Dutertre S et al. | AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. | 2007 | EMBO J. | pmid:17660751 |
| Mochel F et al. | Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. | 2007 | PLoS ONE | pmid:17653274 |
| Pohl T et al. | Effects of the deletion of the Escherichia coli frataxin homologue CyaY on the respiratory NADH:ubiquinone oxidoreductase. | 2007 | BMC Biochem. | pmid:17650323 |
| Chojnacki H | Proton transfer in some periodic molecular systems. | 2007 | J Mol Model | pmid:17479303 |
| Karki S et al. | Powder X-ray diffraction as an emerging method to structurally characterize organic solids. | 2007 | Org. Lett. | pmid:17629292 |
| Lubkoll J and Wennemers H | Mimicry of polyketide synthases--enantioselective 1,4-addition reactions of malonic acid half-thioesters to nitroolefins. | 2007 | Angew. Chem. Int. Ed. Engl. | pmid:17680584 |
| Panee J et al. | The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation. | 2007 | Int. J. Biol. Sci. | pmid:17657281 |
| Yip SF et al. | Room-temperature copper-catalyzed alpha-arylation of malonates. | 2007 | Org. Lett. | pmid:17637034 |
| Koponen IK et al. | Thermodynamic properties of malonic, succinic, and glutaric acids: evaporation rates and saturation vapor pressures. | 2007 | Environ. Sci. Technol. | pmid:17612170 |
| Fortner KC and Shair MD | Stereoelectronic effects dictate mechanistic dichotomy between Cu(II)-catalyzed and enzyme-catalyzed reactions of malonic acid half thioesters. | 2007 | J. Am. Chem. Soc. | pmid:17263375 |
| Huber SG et al. | Carbon suboxide, a highly reactive intermediate from the abiotic degradation of aromatic compounds in soil. | 2007 | Environ. Sci. Technol. | pmid:18075091 |
| Zeevalk GD et al. | Characterization of intracellular elevation of glutathione (GSH) with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease. | 2007 | Exp. Neurol. | pmid:17049515 |
| Kripal R and Singh DK | ESR and optical study of Cu2+ doped calcium malonate dihydrate. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17018262 |
| Deegan C et al. | In vitro cancer chemotherapeutic activity of 1,10-phenanthroline (phen), [Ag2(phen)3(mal)]x2H2O, [Cu(phen)2(mal)]x2H2O and [Mn(phen)2(mal)]x2H2O (malH2=malonic acid) using human cancer cells. | 2007 | Cancer Lett. | pmid:16740357 |