Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Zellweger Syndrome D015211 39 associated lipids
Weight Gain D015430 101 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Meyer KJ et al. Mitochondrial genome-knockout cells demonstrate a dual mechanism of action for the electron transport complex I inhibitor mycothiazole. 2012 Mar Drugs pmid:22690150
Vujčić M et al. A comparative study of DNA binding and cell cycle phase perturbation by the dinuclear complex of Cd(II) with the condensation product of 2-acetylpyridine and malonic acid dihydrazide N',N'(2) -bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. 2011 May-Jun J. Biochem. Mol. Toxicol. pmid:21671309
Deng YF Poly[[[μ(3)-5-(pyridine-4-carboxamido)-isophthalato]{μ(3)-5-[(pyridin-1-ium-4-yl)carbonyl-amino]-isophthalato}-neodymium(III)] dihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22058886
Qiu G et al. Efficient assembly of 1-(1H-imidazol-1-yl)-3-methylene-1H-indenes via tandem reaction of (2-(alkynyl)benzylidene)malonates with imidazoles. 2011 ACS Comb Sci pmid:21247119
Xi ZX et al. Brain cannabinoid CBâ‚‚ receptors modulate cocaine's actions in mice. 2011 Nat. Neurosci. pmid:21785434
Di Bella S et al. Salmonella enterica ssp. arizonae infection in a 43-year-old Italian man with hypoglobulinemia: a case report and review of the literature. 2011 J Med Case Rep pmid:21781321
Aghabozorg H et al. Bis(2,3-diamino-pyridinium) bis-(μ-pyridine-2,6-dicarboxyl-ato)-κO,N,O:O;κO:O,N,O-bis-[aqua-(pyridine-2,6-dicarboxyl-ato-κO,N,O)bis-muthate(III)] tetra-hydrate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21522286
Ringstrand B et al. The preparation of 3-substituted-1,5-dibromopentanes as precursors to heteracyclohexanes. 2011 Beilstein J Org Chem pmid:21512596
Darandeh N and Hadavi E Effect of Pre-Harvest Foliar Application of Citric Acid and Malic Acid on Chlorophyll Content and Post-Harvest Vase Life of Lilium cv. Brunello. 2011 Front Plant Sci pmid:22639626
Takahashi H et al. Evolutionary relationships and functional diversity of plant sulfate transporters. 2011 Front Plant Sci pmid:22629272