Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Zellweger Syndrome D015211 39 associated lipids
Weight Gain D015430 101 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

Download all related citations
Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
pmid:21971499
Wang DZ et al. Homology-Driven Proteomics of Dinoflagellates with Unsequenced Genomes Using MALDI-TOF/TOF and Automated De Novo Sequencing. 2011 Evid Based Complement Alternat Med pmid:21977052
Li C and Zhou HM The role of manganese superoxide dismutase in inflammation defense. 2011 Enzyme Res pmid:21977313
pmid:21979968
Rajeev L et al. Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium. 2011 Genome Biol. pmid:21992415
Edwards TE et al. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. 2011 BMC Struct. Biol. pmid:21995815
pmid:21999912
Sivagnanam K et al. Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose. 2011 Proteome Sci pmid:22008648
Bondia-Pons I et al. Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread. 2011 Nutr J pmid:22011443
Merlino A et al. Improving protein crystal quality by the without-oil microbatch method: crystallization and preliminary X-ray diffraction analysis of glutathione synthetase from Pseudoalteromonas haloplanktis. 2011 Int J Mol Sci pmid:22016660
Troxell B et al. The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets. 2011 BMC Microbiol. pmid:22017966
Ramachandran VK et al. Adaptation of Rhizobium leguminosarum to pea, alfalfa and sugar beet rhizospheres investigated by comparative transcriptomics. 2011 Genome Biol. pmid:22018401
pmid:22020873
Pon J et al. Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control. 2011 Malar. J. pmid:22029897
pmid:22033601
Müller BA and Dhalla NS Mechanisms of the beneficial actions of ischemic preconditioning on subcellular remodeling in ischemic-reperfused heart. 2010 Curr Cardiol Rev pmid:22043201
Deng YF Poly[[[μ(3)-5-(pyridine-4-carboxamido)-isophthalato]{μ(3)-5-[(pyridin-1-ium-4-yl)carbonyl-amino]-isophthalato}-neodymium(III)] dihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22058886
Guo HM 6-Benzyl 4-ethyl 2-chloro-5,6,7,8-tetra-hydro-pyrido[4,3-d]pyrimidine-4,6-di-carboxyl-ate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22065115
Li Z 4,4'-[p-Phenyl-enebis(-oxy)]dibutanoic acid. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22065827
Padalkar VS et al. Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding. 2011 Chem Cent J pmid:22067202
el Khoury A and Atoui A Ochratoxin a: general overview and actual molecular status. 2010 Toxins (Basel) pmid:22069596
Hagos Y and Wolff NA Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity. 2010 Toxins (Basel) pmid:22069672
Liu J et al. Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. 2011 Int J Mol Sci pmid:22072900
Holley AK et al. Manganese superoxide dismutase: guardian of the powerhouse. 2011 Int J Mol Sci pmid:22072939
Roth S Mathematics and biology: a Kantian view on the history of pattern formation theory. 2011 Dev. Genes Evol. pmid:22086125
Giorgio V et al. The effects of idebenone on mitochondrial bioenergetics. 2012 Biochim. Biophys. Acta pmid:22086148
Feng LP and Zhao L 2-Amino-anilinium 2-carb-oxy-acetate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22090933
Zeng WL 5,5'-[(2,4-Dichloro-phen-yl)methyl-ene]bis-(2,2-dimethyl-1,3-dioxane-4,6-dione). 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22090945
Rong T 2,4,6-Trimethyl-anilinium 2-carb-oxy-ethano-ate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22090968
Zeng WL 2,2-Dimethyl-5-(2,3,4-trimeth-oxy-benzyl-idene)-1,3-dioxane-4,6-dione. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22090981
pmid:22092059
Schlüter A et al. Functional genomic analysis unravels a metabolic-inflammatory interplay in adrenoleukodystrophy. 2012 Hum. Mol. Genet. pmid:22095690
Lallous N et al. The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers. 2011 PLoS ONE pmid:22096602
Xue J et al. Novel compound heterozygous mutation of MLYCD in a Chinese patient with malonic aciduria. 2012 Mol. Genet. Metab. pmid:22104738
pmid:22107371
Jeon E et al. Development of Escherichia coli MG1655 strains to produce long chain fatty acids by engineering fatty acid synthesis (FAS) metabolism. 2011 Enzyme Microb. Technol. pmid:22112270
Miller SE et al. The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. 2011 Cell pmid:22118466
Park SR et al. Enhanced flavonoid production in Streptomyces venezuelae via metabolic engineering. 2011 J. Microbiol. Biotechnol. pmid:22127124
Merewitz EB et al. Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation. 2012 J. Exp. Bot. pmid:22131157
Fejes A et al. Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives. 2011 Curr Neuropharmacol pmid:22131946
Amaral AU et al. Ethylmalonic acid impairs brain mitochondrial succinate and malate transport. 2012 Mol. Genet. Metab. pmid:22133302
Whitaker-Menezes D et al. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. 2011 Cell Cycle pmid:22134189
Yadav M et al. Synthesis, characterization and applications of graft copolymer (κ-carrageenan-g-vinylsulfonic acid). 2012 Int. J. Biol. Macromol. pmid:22142792
pmid:22159299
Singh SK et al. Coal Depolymerising Activity and Haloperoxidase Activity of Mn Peroxidase from Fomes durissimus MTCC-1173. 2011 Bioinorg Chem Appl pmid:22162670
Hench J et al. A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans. 2011 PLoS ONE pmid:22162770
Montavon TJ et al. Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers. 2011 Nat Chem pmid:22169871
Schiff M et al. Mouse studies to shape clinical trials for mitochondrial diseases: high fat diet in Harlequin mice. 2011 PLoS ONE pmid:22174907
Shi D et al. A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris. 2011 PLoS ONE pmid:22174908
pmid:22179325
pmid:22196927
Chen HR et al. Poly[[tetra-aqua-μ(4)-fumarato-di-μ(3)-fumarato-dineodymium(III)] trihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22199526
Guo HM 5-tert-Butyl 3-ethyl 1-isopropyl-4,5,6,7-tetra-hydro-1H-pyrazolo-[4,3-c]pyridine-3,5-dicarboxyl-ate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22199750
Myking S et al. Candidate gene analysis of spontaneous preterm delivery: new insights from re-analysis of a case-control study using case-parent triads and control-mother dyads. 2011 BMC Med. Genet. pmid:22208904
Jiang GQ et al. Hexa-μ(2)-acetato-κO:O'-(azido-κN)bis-(methanol-κO)-μ(3)-oxido-trichromium(III) methanol monosolvate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22219738
Li ZS and Ng SW catena-Poly[[[(2,2'-bipyridine-κN,N')cobalt(II)]-μ-(E)-3,3'-(but-2-ene-2,3-di-yl)dibenzoato-κO,O':O'',O'''] hemihydrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22219789
Liu D Poly[[μ(2)-1,2-bis-(4-pyrid-yl)ethene](μ(3)-1,3-phenyl-enediacetato)-cadmium]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22219828
pmid:22220923
pmid:22228032
Yasaka T and Kambara T Different effects of concanavalin A and its succinylated derivative on superoxide release in peritoneal macrophages. 1979 Biochim. Biophys. Acta pmid:222348
Luévano-Martínez LA et al. A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. 2012 Biochem. J. pmid:22236206
pmid:22247027
Yokoi T et al. Formation of octacalcium phosphates with co-incorporated succinate and suberate ions. 2012 Dalton Trans pmid:22249371
Caligiani A et al. 1H NMR fingerprinting of soybean extracts, with emphasis on identification and quantification of isoflavones. 2010 Nutrients pmid:22254020
Irizarry KJ et al. Sequencing and comparative genomic analysis of 1227 Felis catus cDNA sequences enriched for developmental, clinical and nutritional phenotypes. 2012 BMC Genomics pmid:22257742
Zhang YM et al. 5-Carb-oxy-1,3-bis-(carb-oxy-meth-yl)-4-imidazolinium-4-carboxyl-ate. 2012 Acta Crystallogr Sect E Struct Rep Online pmid:22259512
Desvergnes S et al. Synthesis and evaluation of malonate-based inhibitors of phosphosugar-metabolizing enzymes: class II fructose-1,6-bis-phosphate aldolases, type I phosphomannose isomerase, and phosphoglucose isomerase. 2012 Bioorg. Med. Chem. pmid:22269276
Iriyama N et al. Speciation of arsenic trioxide metabolites in peripheral blood and bone marrow from an acute promyelocytic leukemia patient. 2012 J Hematol Oncol pmid:22272800
Zhang YB et al. Geometry analysis and systematic synthesis of highly porous isoreticular frameworks with a unique topology. 2012 Nat Commun pmid:22273680
Schurr A and Gozal E Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress. 2011 Front Pharmacol pmid:22275901
pmid:22278809
Klejnot M and Kozielski F Structural insights into human Kif7, a kinesin involved in Hedgehog signalling. 2012 Acta Crystallogr. D Biol. Crystallogr. pmid:22281744
Vagner T et al. Nucleic Acid-Based Therapy Approaches for Huntington's Disease. 2012 Neurol Res Int pmid:22288011
Yoshida R Design of self-oscillating gels and application to biomimetic actuators. 2010 Sensors (Basel) pmid:22294901
pmid:22309194
Barker BM et al. Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. 2012 BMC Genomics pmid:22309491
pmid:22314823
Kim SH et al. Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction. 2012 BMC Microbiol. pmid:22316246
Peng Y et al. Poly[[μ(2)-1,3-bis-(imidazol-1-ylmeth-yl)benzene][μ(2)-2,2'-dihy-droxy-1,1'-methyl-enebis(naphthalene-3-carboxyl-ato)]zinc]. 2012 Acta Crystallogr Sect E Struct Rep Online pmid:22346812
Wang N et al. Changes in soybean global gene expression after application of lipo-chitooligosaccharide from Bradyrhizobium japonicum under sub-optimal temperature. 2012 PLoS ONE pmid:22348109
pmid:22354501
pmid:22356090
pmid:22360256
Frankel S and Rogina B Indy mutants: live long and prosper. 2012 Front Genet pmid:22363340
Fujii T and Albarède F Ab initio calculation of the Zn isotope effect in phosphates, citrates, and malates and applications to plants and soil. 2012 PLoS ONE pmid:22363478
Zuno-Floriano FG et al. Effect of Acinetobacter sp on metalaxyl degradation and metabolite profile of potato seedlings (Solanum tuberosum L.) alpha variety. 2012 PLoS ONE pmid:22363586
Mitra T et al. Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions. 2012 J Mater Sci Mater Med pmid:22367159
Tovar-y-Romo LB and Tapia R Delayed administration of VEGF rescues spinal motor neurons from death with a short effective time frame in excitotoxic experimental models in vivo. 2012 ASN Neuro pmid:22369757
Hackett NR et al. RNA-Seq quantification of the human small airway epithelium transcriptome. 2012 BMC Genomics pmid:22375630
pmid:22382534
Liu Z et al. The effects of dynamic changes of malonyl ginsenosides on evaluation and quality control of Panax ginseng C.A. Meyer. 2012 J Pharm Biomed Anal pmid:22387101
Totir M et al. Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization. 2012 PLoS ONE pmid:22393408
Tran QM et al. Out of plane distortions of the heme b of Escherichia coli succinate dehydrogenase. 2012 PLoS ONE pmid:22393428
Trushina E et al. Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. 2012 PLoS ONE pmid:22393443
Ashrafian H et al. Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. 2012 Cell Metab. pmid:22405071
Zhang XJ and Guo ML catena-Poly[[bis-(1-methyl-1H-imidazole-κN)zinc]-μ-3-nitro-phthalato-κO:O]. 2012 Acta Crystallogr Sect E Struct Rep Online pmid:22412416
Jin YW and Zhu HL Poly[[penta-aqua-(μ(4)-pyridine-2,4,6-tri-carboxyl-ato)(μ(3)-pyridine-2,4,6-tri-carboxyl-ato)disamarium(III)] mono-hydrate]. 2012 Acta Crystallogr Sect E Struct Rep Online pmid:22412433
Chojkier M et al. Pioglitazone decreases hepatitis C viral load in overweight, treatment naïve, genotype 4 infected-patients: a pilot study. 2012 PLoS ONE pmid:22412837
Ward RA et al. Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation. 2012 J. Med. Chem. pmid:22417091
pmid:22419152