| MeSH term | MeSH ID | Detail |
|---|---|---|
| Memory Disorders | D008569 | 33 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
| Mitochondrial Diseases | D028361 | 25 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Hemorrhagic Fever with Renal Syndrome | D006480 | 3 associated lipids |
| Neoplasms, Muscle Tissue | D009379 | 2 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Barros-Miñones L et al. | Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate. | 2013 | Biochim. Biophys. Acta | pmid:23415811 |
| Yuan HN et al. | Highly enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic trifluoromethyl ketimines: synthesis of β-amino esters and anti-HIV drug DPC 083. | 2013 | Chemistry | pmid:24150893 |
| Sundermann U et al. | Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. | 2013 | ACS Chem. Biol. | pmid:23181268 |
| Barros-Miñones L et al. | Modulation of the ASK1-MKK3/6-p38/MAPK signalling pathway mediates sildenafil protection against chemical hypoxia caused by malonate. | 2013 | Br. J. Pharmacol. | pmid:23186227 |
| Salem AA et al. | Application of quantitative nuclear magnetic resonance spectroscopy for the determination ofamantadine and acyclovir in plasma and pharmaceutical samples. | 2012 Nov-Dec | J AOAC Int | pmid:23451380 |
| Mahendradas P et al. | Unilateral conjunctival ulcer due to Stenotrophomonas maltophilia infection. | 2012 Mar-Apr | Indian J Ophthalmol | pmid:22446910 |
| Kim SH et al. | Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction. | 2012 | BMC Microbiol. | pmid:22316246 |
| Ruiz M et al. | A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. | 2012 | PLoS ONE | pmid:23056435 |
| Yokoi T et al. | Formation of octacalcium phosphates with co-incorporated succinate and suberate ions. | 2012 | Dalton Trans | pmid:22249371 |
| Luévano-MartÃnez LA et al. | A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. | 2012 | Biochem. J. | pmid:22236206 |
| Caricato M et al. | Synthesis and anion recognition properties of shape-persistent binaphthyl-containing chiral macrocyclic amides. | 2012 | Beilstein J Org Chem | pmid:23015847 |
| Agarwal HK et al. | Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22858097 |
| Scalliet G et al. | Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. | 2012 | PLoS ONE | pmid:22536383 |
| Laurido C et al. | Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model. | 2012 | ScientificWorldJournal | pmid:22536130 |
| Okoli AS et al. | Effects of human and porcine bile on the proteome of Helicobacter hepaticus. | 2012 | Proteome Sci | pmid:22533459 |
| Pauly MC et al. | Restoration of the striatal circuitry: from developmental aspects toward clinical applications. | 2012 | Front Cell Neurosci | pmid:22529778 |
| Nguyen Q et al. | Rh2(II)-catalyzed intramolecular aliphatic C-H bond amination reactions using aryl azides as the N-atom source. | 2012 | J. Am. Chem. Soc. | pmid:22519742 |
| Barker BM et al. | Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. | 2012 | BMC Genomics | pmid:22309491 |
| Peng Y et al. | Poly[[μ(2)-1,3-bis-(imidazol-1-ylmeth-yl)benzene][μ(2)-2,2'-dihy-droxy-1,1'-methyl-enebis(naphthalene-3-carboxyl-ato)]zinc]. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22346812 |
| Vagner T et al. | Nucleic Acid-Based Therapy Approaches for Huntington's Disease. | 2012 | Neurol Res Int | pmid:22288011 |