Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Neoplasms, Muscle Tissue D009379 2 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Teratoma D013724 4 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Abscess D000038 13 associated lipids
Neoplasms D009369 13 associated lipids
Ischemia D007511 18 associated lipids
Brain Edema D001929 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
McDowell EM Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. A morphological and histochemical study of the pars recta during malonate poisoning. 1974 Virchows Arch B Cell Pathol pmid:4210043
Giurov B [Biochemical characteristics of the causative agent of fowl typhoid]. 1986 Vet Med Nauki pmid:3765371
Dosch W Rapid and direct gas chromatographic determination of oxalic acid in urine. 1979 Urol. Res. pmid:505684
Zinich VN and Zobova NV [Activation of succinate oxidase in the inner membrane of rat liver mitochondria]. 1989 May-Jun Ukr. Biokhim. Zh. pmid:2546308
Davydov VV [Metabolism of free malonic acid in rat tissues]. 1991 Jan-Feb Ukr. Biokhim. Zh. pmid:2028517
Davydov VV et al. [The effect of malonate on lipid biosynthesis in the liver]. 1992 Nov-Dec Ukr. Biokhim. Zh. pmid:1488816
Mandrik KA et al. [Kinetics of the inhibition of succinate dehydrogenase in bull adrenal cortex by malonate and oxaloacetate]. 1983 Sep-Oct Ukr. Biokhim. Zh. pmid:6636310
Akopova OV et al. [Estimation of ATP-dependent K(+)-channel contribution to potential-dependent potassium uptake in the rat brain mitochondria]. 2014 Jan-Feb Ukr Biochem J pmid:24834715
Polygalova OO et al. [Wheat root cells functioning under inhibition of I and II complexes of mitochondrial respiratory chain]. 2007 Tsitologiia pmid:17926562
Bufetov EN et al. [Effect of malonate on the structural and functional changes of wheat Triticum aestivum L. root cells]. 2004 Tsitologiia pmid:15704878