Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Myking S et al. | Candidate gene analysis of spontaneous preterm delivery: new insights from re-analysis of a case-control study using case-parent triads and control-mother dyads. | 2011 | BMC Med. Genet. | pmid:22208904 |
Guo HM | 5-tert-Butyl 3-ethyl 1-isopropyl-4,5,6,7-tetra-hydro-1H-pyrazolo-[4,3-c]pyridine-3,5-dicarboxyl-ate. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22199750 |
Chen HR et al. | Poly[[tetra-aqua-μ(4)-fumarato-di-μ(3)-fumarato-dineodymium(III)] trihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22199526 |
Shi D et al. | A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris. | 2011 | PLoS ONE | pmid:22174908 |
Schiff M et al. | Mouse studies to shape clinical trials for mitochondrial diseases: high fat diet in Harlequin mice. | 2011 | PLoS ONE | pmid:22174907 |
Montavon TJ et al. | Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers. | 2011 | Nat Chem | pmid:22169871 |
Hench J et al. | A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans. | 2011 | PLoS ONE | pmid:22162770 |
Merlino A et al. | Improving protein crystal quality by the without-oil microbatch method: crystallization and preliminary X-ray diffraction analysis of glutathione synthetase from Pseudoalteromonas haloplanktis. | 2011 | Int J Mol Sci | pmid:22016660 |
Sivagnanam K et al. | Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose. | 2011 | Proteome Sci | pmid:22008648 |
Rajeev L et al. | Systematic mapping of two component response regulators to gene targets in a model sulfate reducing bacterium. | 2011 | Genome Biol. | pmid:21992415 |
Li C and Zhou HM | The role of manganese superoxide dismutase in inflammation defense. | 2011 | Enzyme Res | pmid:21977313 |
Wang DZ et al. | Homology-Driven Proteomics of Dinoflagellates with Unsequenced Genomes Using MALDI-TOF/TOF and Automated De Novo Sequencing. | 2011 | Evid Based Complement Alternat Med | pmid:21977052 |
Prakash M et al. | Crystal growth, structural, optical, dielectric and thermal studies of an amino acid based organic NLO material: L-phenylalanine L-phenylalaninium malonate. | 2011 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:21943710 |
Sy A et al. | Poly[di-μ-aqua-diaqua-di-μ(6)-malonato-cobalt(II)dipotassium(I)]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21754320 |
Zhou YH | Di-μ-glutarato-κO:O-bis-[aqua-(1,10-phenanthroline-κN,N')copper(II)]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21753943 |
Hutcheson SW et al. | Carbohydrase systems of Saccharophagus degradans degrading marine complex polysaccharides. | 2011 | Mar Drugs | pmid:21731555 |
Lim IT and Choi KY | One-dimensional hydrogen-bonded infinite chain from nickel(II) tetraaza macrocyclic complex and 1,2-cyclopentanedicarboxylate ligand. | 2011 | Int J Mol Sci | pmid:21731438 |
Brand MD and Nicholls DG | Assessing mitochondrial dysfunction in cells. | 2011 | Biochem. J. | pmid:21726199 |
Lin S and Cronan JE | Closing in on complete pathways of biotin biosynthesis. | 2011 | Mol Biosyst | pmid:21437340 |
Matar-Merheb R et al. | Structuring detergents for extracting and stabilizing functional membrane proteins. | 2011 | PLoS ONE | pmid:21483854 |
Sorokin DY et al. | Culturable diversity of lithotrophic haloalkaliphilic sulfate-reducing bacteria in soda lakes and the description of Desulfonatronum thioautotrophicum sp. nov., Desulfonatronum thiosulfatophilum sp. nov., Desulfonatronovibrio thiodismutans sp. nov., and Desulfonatronovibrio magnus sp. nov. | 2011 | Extremophiles | pmid:21479878 |
Zhao J et al. | MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. | 2011 | Plant Cell | pmid:21467581 |
Ling AS et al. | A zinc finger protein, TbZC3H20, stabilizes two developmentally regulated mRNAs in trypanosomes. | 2011 | J. Biol. Chem. | pmid:21467035 |
Gallo M et al. | MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. | 2011 | PLoS ONE | pmid:21448454 |
Kurakin A | The self-organizing fractal theory as a universal discovery method: the phenomenon of life. | 2011 | Theor Biol Med Model | pmid:21447162 |
Damrauer SM et al. | A20 modulates lipid metabolism and energy production to promote liver regeneration. | 2011 | PLoS ONE | pmid:21437236 |
Pryde KR and Hirst J | Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer. | 2011 | J. Biol. Chem. | pmid:21393237 |
Iacopetta D et al. | A novel subfamily of mitochondrial dicarboxylate carriers from Drosophila melanogaster: biochemical and computational studies. | 2011 | Biochim. Biophys. Acta | pmid:21130726 |
Hering-Smith KS et al. | Calcium sensitivity of dicarboxylate transport in cultured proximal tubule cells. | 2011 | Am. J. Physiol. Renal Physiol. | pmid:21123491 |
Pagani I et al. | Complete genome sequence of Marivirga tractuosa type strain (H-43). | 2011 | Stand Genomic Sci | pmid:21677852 |
Tomasiak TM et al. | Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase. | 2011 | J. Biol. Chem. | pmid:21098488 |
Kim SH et al. | Metabolic profiling and predicting the free radical scavenging activity of guava (Psidium guajava L.) leaves according to harvest time by 1H-nuclear magnetic resonance spectroscopy. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21670527 |
Edwards TE et al. | Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. | 2011 | BMC Struct. Biol. | pmid:21995815 |
Bondia-Pons I et al. | Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread. | 2011 | Nutr J | pmid:22011443 |
VujÄić M et al. | A comparative study of DNA binding and cell cycle phase perturbation by the dinuclear complex of Cd(II) with the condensation product of 2-acetylpyridine and malonic acid dihydrazide N',N'(2) -bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. | 2011 May-Jun | J. Biochem. Mol. Toxicol. | pmid:21671309 |
Führs H et al. | Functional associations between the metabolome and manganese tolerance in Vigna unguiculata. | 2012 | J. Exp. Bot. | pmid:21934118 |
Callahan DL et al. | Elemental and metabolite profiling of nickel hyperaccumulators from New Caledonia. | 2012 | Phytochemistry | pmid:22795763 |
Shevchenko A et al. | A new cocrystal and salts of itraconazole: comparison of solid-state properties, stability and dissolution behavior. | 2012 | Int J Pharm | pmid:22750429 |
Liu Q et al. | Structural effect and mechanism of C70-carboxyfullerenes as efficient sensitizers against cancer cells. | 2012 | Small | pmid:22508680 |
Mitra T et al. | Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions. | 2012 | J Mater Sci Mater Med | pmid:22367159 |
Lapanje K et al. | Bis(acetato-κO)bis-[2-(pyridin-2-yl)ethanol-κ(2)N,O]copper(II). | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22590106 |
Benkanoun A et al. | Intra- and supra-molecular inter-actions in cis,mer-diaqua-tris-(1H-imidazole-κN(3))(terephthalato-κO)cobalt(II) monohydrate. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22589841 |
Liew CW et al. | Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis. | 2012 | J. Biol. Chem. | pmid:22589546 |
Anand K et al. | Structural analyses of the Slm1-PH domain demonstrate ligand binding in the non-canonical site. | 2012 | PLoS ONE | pmid:22574179 |
Moldes D et al. | Role of laccase and low molecular weight metabolites from Trametes versicolor in dye decolorization. | 2012 | ScientificWorldJournal | pmid:22566767 |
Jin YW and Zhu HL | Poly[[penta-aqua-(μ(4)-pyridine-2,4,6-tri-carboxyl-ato)(μ(3)-pyridine-2,4,6-tri-carboxyl-ato)disamarium(III)] mono-hydrate]. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22412433 |
Zhang XJ and Guo ML | catena-Poly[[bis-(1-methyl-1H-imidazole-κN)zinc]-μ-3-nitro-phthalato-κO:O]. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22412416 |
Ashrafian H et al. | Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. | 2012 | Cell Metab. | pmid:22405071 |
Trushina E et al. | Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. | 2012 | PLoS ONE | pmid:22393443 |
Merewitz EB et al. | Elevated cytokinin content in ipt transgenic creeping bentgrass promotes drought tolerance through regulating metabolite accumulation. | 2012 | J. Exp. Bot. | pmid:22131157 |