Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
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Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Matern U et al. | Conformational changes of apigenin 7-O-(6-O-malonylglucoside), a vacuolar pigment from parsley, with solvent composition and proton concentration. | 1983 | Eur. J. Biochem. | pmid:6303788 |
| Bindoli A et al. | Mitochondrial lipid peroxidation by cumene hydroperoxide and its prevention by succinate. | 1982 | Biochim. Biophys. Acta | pmid:6289887 |
| Eriksson B et al. | Pyrophosphate analogues as inhibitors of herpes simplex virus type 1 DNA polymerase. | 1980 | Biochim. Biophys. Acta | pmid:6245699 |
| Malviya AN et al. | Observations on the oxidoreduction of the two cytochromes b in cytochrome c-deficient mitochondria and submitochondrial particles. | 1980 | Biochim. Biophys. Acta | pmid:6243963 |
| Costa LE et al. | Stoichiometry of mitochondrial H+ translocation coupled to succinate oxidation at level flow. | 1984 | J. Biol. Chem. | pmid:6232269 |
| Yamaguchi M et al. | Role of zinc as an activator of mitochondrial function in rat liver. | 1982 | Biochem. Pharmacol. | pmid:6212062 |
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| Wingrove DE et al. | Glucagon effects on the membrane potential and calcium uptake rate of rat liver mitochondria. | 1984 | J. Biol. Chem. | pmid:6204980 |
| Calderon-Attas P et al. | In vitro effects of ethanol and ethanol metabolism in the rat pancreas. | 1980 | Biochim. Biophys. Acta | pmid:6165387 |
| Brown GK et al. | Malonyl coenzyme A decarboxylase deficiency. | 1984 | J. Inherit. Metab. Dis. | pmid:6145813 |
| Schoolwerth AC et al. | Glutamate transprot in rat kidney mitochondria. | 1983 | J. Biol. Chem. | pmid:6130095 |
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| Journet EP et al. | Glutamate metabolism triggered by oxaloacetate in intact plant mitochondria. | 1982 | Arch. Biochem. Biophys. | pmid:6123300 |
| Lindmark DG | Energy metabolism of the anaerobic protozoon Giardia lamblia. | 1980 | Mol. Biochem. Parasitol. | pmid:6108507 |
| Duszyński J et al. | Homeostasis of the protonmotive force in phosphorylating mitochondria. | 1984 | Biochim. Biophys. Acta | pmid:6095904 |
| Williams WL et al. | Indirect inactivation of rabbit reticulocyte initiation factor eIF-2 by helenalin and bis(helenalinyl) malonate. | 1984 | Biochemistry | pmid:6095903 |
| Huang EM et al. | Succinate potentiates the action of platelet agonists. | 1984 | Thromb. Res. | pmid:6095483 |
| Ksenzenko M et al. | Relationships between the effects of redox potential, alpha-thenoyltrifluoroacetone and malonate on O(2) and H2O2 generation by submitochondrial particles in the presence of succinate and antimycin. | 1984 | FEBS Lett. | pmid:6090204 |
| Tripathi P et al. | Investigation of effect of alpha-naphthylamine and beta-naphthylamine on organic acids formation of self-sustaining coacervates. | 1979 | Zentralbl Bakteriol Naturwiss | pmid:573037 |
| Hussa RO | Effects of antimicrotubule agents, potassium and inhibitors of energy production on hCG secretion. | 1979 | In Vitro | pmid:572336 |
| Sam CT | Effect of malonate and maleate on growth and brefeldin A formation in Curvularia lunata. | 1978 | Folia Microbiol. (Praha) | pmid:566696 |
| Quehenberger P | The influence of carbon dioxide, bicarbonate and other buffers on the potential of antimony microelectrodes. | 1977 | Pflugers Arch. | pmid:558586 |
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| Harris P | The interpretation of the distribution of radioactivity between carboxyl and alkyl carbon in fatty acids, following exposure to 14C-labelled acetate or malonate. | 1979 | J. Mol. Cell. Cardiol. | pmid:522139 |
| Narayanan N and Eapen J | Effect of malonate, succinate and glucose, in vivo, on the uptake of Cesium-137 by pigeon (Columba livia) muscles. | 1971 | J. Radiat. Res. | pmid:5150020 |
| Vanni P et al. | Studies on isocitrate lyase isolated from Lupinus cotyledons. | 1979 | Can. J. Biochem. | pmid:509354 |
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| Dey SK and Deb C | Effect of sodium malonate on ovarian dehydrogenases. A histochemical study. | 1972 | Anat Anz | pmid:5063563 |
| McDowell EM | Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. II. Effects of sodium malonate on proximal convoluted tubule. | 1972 | Am. J. Pathol. | pmid:5061663 |
| Dosch W | Rapid and direct gas chromatographic determination of oxalic acid in urine. | 1979 | Urol. Res. | pmid:505684 |
| Sluse FE et al. | Mechanism of the exchanges catalysed by the oxoglutarate translocatory of rat-heart mitochondria. Kinetics of the exchange reactions between 2-oxoglutarate, malate and malonate. | 1972 | Eur. J. Biochem. | pmid:5039837 |
| Rafalski A and Raczyñska-Bojanowska K | Synthesis of malonate and methylmalonate and the formation of polyene antibiotics. | 1972 | Acta Biochim. Pol. | pmid:5036391 |
| Dey SK et al. | Testicular dehydrogenases in toads after malonate treatment. | 1971 | Acta Histochem. | pmid:4998164 |
| Buck R et al. | [Degradation and biosynthesis of L-phenylalanine by chloridazon-degrading bacteria]. | 1979 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:488918 |
| Calderon P et al. | In vitro lipid metabolism in the rat pancreas. II. Effects of secretagogues on fatty acid metabolism, net lipolysis and ATP levels. | 1979 | Biochim. Biophys. Acta | pmid:486518 |
| von Nicolai H and Zilliken F | [Gas chromatographic determination of oxalic acid, malonic acid and succinic acid in biological material]. | 1974 | J. Chromatogr. | pmid:4836242 |
| Ross JA and Tweedy BG | Malonic acid conjugation by soil microorganisms of a pesticide-derived aniline moiety. | 1973 | Bull Environ Contam Toxicol | pmid:4755262 |
| Chatterjee S et al. | Studies on protein and nucleic acid contents of toad testes following administration of sodium malonate. | 1973 | Endocrinol. Jpn. | pmid:4740601 |
| Rae IC et al. | Utilization of iron gallate and other organic iron complexes by bacteria from water supplies. | 1973 | Appl Microbiol | pmid:4716725 |
| Thabrew MI et al. | The effect of malonate on succinate metabolism in the excised gill of Carcinus maenas. | 1973 | Comp. Biochem. Physiol., B | pmid:4709984 |
| Preuss HG et al. | Effects of glutamine deamination on glutamine deamidation in rat kidney slices. | 1973 | J. Clin. Invest. | pmid:4693645 |
| Dey SK et al. | Pentose phosphate pathway and steroidogenesis in the immature rat ovary after malonate treatment. | 1972 | Acta Endocrinol. | pmid:4677789 |
| Anthony C and Dunstan PM | A novel pathway for bacterial growth on malonate and beta-hydroxybutyrate. | 1972 | Biochem. J. | pmid:4655436 |
| Blazevic DJ et al. | Evaluation of the PathoTec "Rapid I-D System". | 1973 | Appl Microbiol | pmid:4588196 |
| Denisenko TV et al. | [Decarboxylation of malonyl-CoA and biosynthesis of mevalonic acid in rat liver]. | 1979 | Biokhimiia | pmid:454714 |
| Prahoveanu E et al. | The effect of malonate on succinic dehydrogenase (SDH) activity during the multiplication of influenza and herpes viruses in the embryonate hen egg. | 1974 | Rev Roum Virol | pmid:4465902 |
| Crompton M et al. | The transport of sulphate and sulphite in rat liver mitochondria. | 1974 | Biochem. J. | pmid:4441366 |
| Ninomiya K et al. | Phosphorus in organic synthesis. IX. On the mechanism of esterification of malonic acid half esters by diphenyl phosphorazidate. | 1974 | Chem. Pharm. Bull. | pmid:4430027 |
| Ninomiya K et al. | Amino acids and peptides. XII. Phosphorus in organic synthesis. VIII. Reaction of malonic acid half esters with diphenyl phosphorazidate. | 1974 | Chem. Pharm. Bull. | pmid:4422651 |