| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Abscess | D000038 | 13 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Oyedotun KS and Lemire BD | The Saccharomyces cerevisiae succinate-ubiquinone reductase contains a stoichiometric amount of cytochrome b562. | 1999 | FEBS Lett. | pmid:9929002 |
| Hoenke S and Dimroth P | Formation of catalytically active acetyl-S-malonate decarboxylase requires malonyl-coenzyme A:acyl carrier protein transacylase as auxiliary enzyme [corrected]. | 1999 | Eur. J. Biochem. | pmid:9914491 |
| Bruce-Keller AJ et al. | Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. | 1999 | Ann. Neurol. | pmid:9894871 |
| Maragos WF et al. | 6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions. | 1998 | Exp. Neurol. | pmid:9878198 |
| Gao J et al. | Cloning and mutational analysis of human malonyl-coenzyme A decarboxylase. | 1999 | J. Lipid Res. | pmid:9869665 |
| Matharu AL et al. | MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor. | 1998 | Chem. Biol. | pmid:9862793 |
| Kolb S et al. | The fermenting bacterium Malonomonas rubra is phylogenetically related to sulfur-reducing bacteria and contains a c-type cytochrome similar to those of sulfur and sulfate reducers. | 1998 | Syst. Appl. Microbiol. | pmid:9841124 |
| An JH and Kim YS | A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli. | 1998 | Eur. J. Biochem. | pmid:9826185 |
| Zeevalk GD et al. | Excitotoxicity and oxidative stress during inhibition of energy metabolism. | 1998 | Dev. Neurosci. | pmid:9778583 |
| Simonyan RA and Skulachev VP | Thermoregulatory uncoupling in heart muscle mitochondria: involvement of the ATP/ADP antiporter and uncoupling protein. | 1998 | FEBS Lett. | pmid:9771898 |
| Rutkoski A and Jaworski JG | An improved synthesis of malonyl-coenzyme A. | 1978 | Anal. Biochem. | pmid:9762122 |
| Bonkowsky HL and Pomeroy JS | Assay of delta-aminolevulinic acid synthetase in homogenates of mouse, rat, and human liver: species differences in requirement for an exogenous succinyl-CoA-generating system. | 1978 | Anal. Biochem. | pmid:9762086 |
| Hofrichter M et al. | Oxidative decomposition of malonic acid as basis for the action of manganese peroxidase in the absence of hydrogen peroxide. | 1998 | FEBS Lett. | pmid:9742955 |
| Hariharan M and Allewell NM | Effects of the T-->R transition on the electrostatic properties of E. coli aspartate transcarbamylase. | 1998 | Proteins | pmid:9714159 |
| Gregg AR et al. | Combined malonic and methylmalonic aciduria with normal malonyl-coenzyme A decarboxylase activity: a case supporting multiple aetiologies. | 1998 | J. Inherit. Metab. Dis. | pmid:9700595 |
| Prorok M and Castellino FJ | Thermodynamics of binding of calcium, magnesium, and zinc to the N-methyl-D-aspartate receptor ion channel peptidic inhibitors, conantokin-G and conantokin-T. | 1998 | J. Biol. Chem. | pmid:9677382 |
| Aime S et al. | NMR and luminescence studies on the formation of ternary adducts between HSA and Ln(III)-malonate complexes. | 1998 | Biochim. Biophys. Acta | pmid:9630476 |
| Cox RB and Quayle JR | Synthesis and hydrolysis of malyl-coenzyme A by Pseudomonas AM1: an apparent malate synthase activity. | 1976 | J. Gen. Microbiol. | pmid:956773 |
| Yu HL et al. | Stimulation of ammonia production and excretion in the rabbit by inorganic phosphate. Study of control mechanisms. | 1976 | J. Clin. Invest. | pmid:956385 |
| Lecanu L et al. | Deleterious Ca-independent NOS activity after oxidative stress in rat striatum. | 1998 | Neuroreport | pmid:9512406 |