| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Abscess | D000038 | 13 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Schulz JB et al. | Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia. | 1998 | Cell Death Differ. | pmid:10203688 |
| Turnbull LB et al. | Excretion and biotransformation of carboxymethyl-cysteine in rat, dog, monkey and man. | 1978 | Xenobiotica | pmid:102086 |
| Matthews RT et al. | Novel free radical spin traps protect against malonate and MPTP neurotoxicity. | 1999 | Exp. Neurol. | pmid:10222114 |
| Chohnan S et al. | Cloning and characterization of mdc genes encoding malonate decarboxylase from Pseudomonas putida. | 1999 | FEMS Microbiol. Lett. | pmid:10339824 |
| Lu GW et al. | Alteration of oxygen consumption and energy metabolism during repetitive exposure of mice to hypoxia. | 1999 | Neurochem. Res. | pmid:10344590 |
| Markova OV et al. | The anion-carrier mediated uncoupling effect of dicarboxylic fatty acids in liver mitochondria depends on the position of the second carboxyl group. | 1999 | Biochemistry Mosc. | pmid:10381619 |
| Maragos WF et al. | Clorgyline and deprenyl attenuate striatal malonate and 3-nitropropionic acid lesions. | 1999 | Brain Res. | pmid:10407109 |
| Kristensen JH et al. | Separation of (2)H MAS NMR spectra by two-dimensional spectroscopy. | 1999 | J. Magn. Reson. | pmid:10423369 |
| Palmieri L et al. | Identification of the yeast mitochondrial transporter for oxaloacetate and sulfate. | 1999 | J. Biol. Chem. | pmid:10428783 |
| Tao Y et al. | Effects of glucagon on axoplasmic transport in mouse superior cervical ganglion cells. | 1999 | Neuroreport | pmid:10439471 |
| Lahnsteiner F et al. | Sperm metabolism of the telost fishes Chalcalburnus chalcoides and Oncorhynchus mykiss and its relation to motility and viability. | 1999 | J. Exp. Zool. | pmid:10451423 |
| Ferger B et al. | Malonate-induced generation of reactive oxygen species in rat striatum depends on dopamine release but not on NMDA receptor activation. | 1999 | J. Neurochem. | pmid:10461928 |
| Moreno-Sánchez R et al. | Determining and understanding the control of flux. An illustration in submitochondrial particles of how to validate schemes of metabolic control. | 1999 | Eur. J. Biochem. | pmid:10491087 |
| Handa S et al. | Stereochemical course of biotin-independent malonate decarboxylase catalysis. | 1999 | Arch. Biochem. Biophys. | pmid:10496981 |
| O'Brien DP et al. | Malonic aciduria in Maltese dogs: normal methylmalonic acid concentrations and malonyl-CoA decarboxylase activity in fibroblasts. | 1999 | J. Inherit. Metab. Dis. | pmid:10604140 |
| Hinz W et al. | Properties of the human long and short isoforms of the uncoupling protein-3 expressed in yeast cells. | 1999 | FEBS Lett. | pmid:10622736 |
| Klivenyi P et al. | Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. | 2000 | J. Neurosci. | pmid:10627575 |
| Garle MJ et al. | Stimulation of dichlorofluorescin oxidation by capsaicin and analogues in RAW 264 monocyte/macrophages: lack of involvement of the vanilloid receptor. | 2000 | Biochem. Pharmacol. | pmid:10660122 |
| Yang WC et al. | Simultaneous determination of polycarboxylic acids by capillary electrophoresis with a copper electrode. | 2000 | J Chromatogr A | pmid:10670726 |
| Gueguen V et al. | Fatty acid and lipoic acid biosynthesis in higher plant mitochondria. | 2000 | J. Biol. Chem. | pmid:10671542 |
| Maragos WF et al. | Does dopamine contribute to striatal damage caused by impaired mitochondrial function? | 1999 | Ann. N. Y. Acad. Sci. | pmid:10672263 |
| Zeevalk GD et al. | Oxidative stress during energy impairment in mesencephalic cultures is not a downstream consequence of a secondary excitotoxicity. | 2000 | Neuroscience | pmid:10683571 |
| Zeevalk GD et al. | NMDA receptors modulate dopamine loss due to energy impairment in the substantia nigra but not striatum. | 2000 | Exp. Neurol. | pmid:10686083 |
| Burrows KB et al. | Central administration of methamphetamine synergizes with metabolic inhibition to deplete striatal monoamines. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688597 |
| Suraveratum N et al. | Purification and characterization of Plasmodium falciparum succinate dehydrogenase. | 2000 | Mol. Biochem. Parasitol. | pmid:10693744 |
| Kaal EC et al. | Chronic mitochondrial inhibition induces selective motoneuron death in vitro: a new model for amyotrophic lateral sclerosis. | 2000 | J. Neurochem. | pmid:10693948 |
| Fitzgerald JW et al. | Reversal of succinate-mediated catabolite repression of alkylsulfatase in Pseudomonas aeruginosa by 2,4-dinitrophenol and by sodium malonate. | 1978 | Can. J. Microbiol. | pmid:106946 |
| Malik N et al. | Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. | 2000 | J Control Release | pmid:10699277 |
| Malcon C et al. | Neuroprotective effects of creatine administration against NMDA and malonate toxicity. | 2000 | Brain Res. | pmid:10727643 |
| Gougoux A et al. | Maleate-induced bicarbonaturia in the dog: a carbonic anhydrase-independene effect. | 1976 | Am. J. Physiol. | pmid:10734 |
| Uyemura SA et al. | Oxidative phosphorylation, Ca(2+) transport, and fatty acid-induced uncoupling in malaria parasites mitochondria. | 2000 | J. Biol. Chem. | pmid:10734123 |
| Moy LY et al. | Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures. | 2000 | J. Neurochem. | pmid:10737624 |
| Guidetti P et al. | In situ produced 7-chlorokynurenate provides protection against quinolinate- and malonate-induced neurotoxicity in the rat striatum. | 2000 | Exp. Neurol. | pmid:10785450 |
| Lin LZ et al. | Liquid chromatography-electrospray ionization mass spectrometry study of the flavonoids of the roots of Astragalus mongholicus and A. membranaceus. | 2000 | J Chromatogr A | pmid:10823504 |
| Bew SP et al. | Kinetic resolution of alpha-acetoxy carboxylic acids with homochiral SuperQuats. | 2000 | Chirality | pmid:10824175 |
| Sett S et al. | Avirulent mutants of Macrophomina phaseolina and Aspergillus fumigatus initiate infection in Phaseolus mungo in the presence of phaseolinone; levamisole gives protection. | 2000 | J. Biosci. | pmid:10824201 |
| Kuijt J et al. | Quenched phosphorescence, a new detection method in capillary electrophoresis. | 2000 | Electrophoresis | pmid:10826674 |
| Koo HM and Kim YS | Identification of active-site residues in Bradyrhizobium japonicum malonyl-coenzyme A synthetase. | 2000 | Arch. Biochem. Biophys. | pmid:10871057 |
| Andreassen OA et al. | Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant. | 2000 | J. Neurochem. | pmid:10899963 |
| Nath R et al. | Processing of cdk5 activator p35 to its truncated form (p25) by calpain in acutely injured neuronal cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10903889 |
| Dongmei H et al. | Synthesis and analgesic activity of N,N'-dicarbonyltryptamines. | 2000 | Prep. Biochem. Biotechnol. | pmid:10919562 |
| Jung JW et al. | The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies. | 2000 | Protein Sci. | pmid:10933494 |
| Li J and Copeland L | Role of malonate in chickpeas. | 2000 | Phytochemistry | pmid:10963451 |
| Aime S et al. | Ternary Gd(III)L-HSA adducts: evidence for the replacement of inner-sphere water molecules by coordinating groups of the protein. Implications for the design of contrast agents for MRI. | 2000 | J. Biol. Inorg. Chem. | pmid:10968620 |
| Sawai S et al. | Spontaneous symmetry breaking turing-type pattern formation in a confined Dictyostelium cell mass. | 2000 | Phys. Rev. Lett. | pmid:10970500 |
| Knobling A et al. | Malonyl and palmityl transferase-less mutants of the yeast fatty-acid-synthetase complex. | 1975 | Eur. J. Biochem. | pmid:1100391 |
| Chaimbault C et al. | Physicochemical and crystallographic evidence for polymorphism of the racemic ethyl (2-chloromethyl-2,3-dihydro-5H-oxazolo [3, 2-a]pyrimidin-5-one)-6-carboxylate. | 2000 | J Pharm Sci | pmid:11015694 |
| Ouyang Q et al. | Transition from spirals to defect-mediated turbulence driven by a doppler instability. | 2000 | Phys. Rev. Lett. | pmid:11017437 |
| Meldrum A et al. | Age-dependence of malonate-induced striatal toxicity. | 2000 | Exp Brain Res | pmid:11045358 |