| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Abscess | D000038 | 13 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chatnaparat T et al. | Global Pattern of Gene Expression of Xanthomonas axonopodis pv. glycines Within Soybean Leaves. | 2016 | Mol. Plant Microbe Interact. | pmid:27003800 |
| pmid:27013280 | ||||
| Aoyama H | Distribution and excretion of thallium after oral and intraperitoneal administration of thallous malonate and thallous sulfate in hamsters. | 1989 | Bull Environ Contam Toxicol | pmid:2706357 |
| Xu JY et al. | Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. | 2016 | J. Proteome Res. | pmid:27090497 |
| pmid:27093562 | ||||
| pmid:27183143 | ||||
| Turrens JF | The role of succinate in the respiratory chain of Trypanosoma brucei procyclic trypomastigotes. | 1989 | Biochem. J. | pmid:2719653 |
| pmid:27244270 | ||||
| pmid:27380367 | ||||
| ZubirÃa MG et al. | Relationship between the Balance of Hypertrophic/Hyperplastic Adipose Tissue Expansion and the Metabolic Profile in a High Glucocorticoids Model. | 2016 | Nutrients | pmid:27384583 |
| pmid:27487922 | ||||
| Oswald CB et al. | Disposition of cisplatin derivatives -3H-cis-1,2-diaminocyclohexanedichloroplatinum (II) and 3H-cis-1,2-diaminocyclohexanemalonatoplatinum (II) in BDF1 mice. | 1989 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:2749002 |
| pmid:27502893 | ||||
| Ando M and Itoh T | Changes of amino acid by the deprivation of energy sources in the cerebral cortex. | 1989 | Brain Dev. | pmid:2751063 |
| pmid:27632703 | ||||
| Geller DA et al. | Binding of calcium by organic anions, determined by perturbation of the equilibrium solubility of [14C]calcium oxalate. | 1989 | Clin. Chim. Acta | pmid:2766550 |
| pmid:27856641 | ||||
| pmid:27939684 | ||||
| pmid:27979291 | ||||
| pmid:28025199 | ||||
| Indiveri C et al. | Kinetics of the reconstituted dicarboxylate carrier from rat liver mitochondria. | 1989 | Biochim. Biophys. Acta | pmid:2804097 |
| Bruze M and Gruvberger B | Patch testing with degradation products of Kathon CG. | 1989 | Contact Derm. | pmid:2805673 |
| pmid:28134976 | ||||
| Wang J et al. | Comparative proteomic and metabolomic analysis of Streptomyces tsukubaensis reveals the metabolic mechanism of FK506 overproduction by feeding soybean oil. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28175948 |
| Carlsen BD et al. | Synthesis of malate from phosphoenolpyruvate by rabbit liver mitochondria: implications for lipogenesis. | 1988 | Biochim. Biophys. Acta | pmid:2831992 |
| Murphy MP and Brand MD | Membrane-potential-dependent changes in the stoichiometry of charge translocation by the mitochondrial electron transport chain. | 1988 | Eur. J. Biochem. | pmid:2836195 |
| Murphy MP and Brand MD | The stoichiometry of charge translocation by cytochrome oxidase and the cytochrome bc1 complex of mitochondria at high membrane potential. | 1988 | Eur. J. Biochem. | pmid:2836196 |
| Woelders H et al. | Unique relationships between the rates of oxidation and phosphorylation and the protonmotive force in rat-liver mitochondria. | 1988 | Biochim. Biophys. Acta | pmid:2837288 |
| pmid:28479296 | ||||
| Brand MD et al. | Control of respiration in non-phosphorylating mitochondria is shared between the proton leak and the respiratory chain. | 1988 | Biochem. J. | pmid:2849419 |
| pmid:28499743 | ||||
| Hafner RP et al. | Altered relationship between protonmotive force and respiration rate in non-phosphorylating liver mitochondria isolated from rats of different thyroid hormone status. | 1988 | Eur. J. Biochem. | pmid:2850181 |
| Donaldson WE | Biotin effects on fatty acid synthesis in chicks. | 1985 | Ann. N. Y. Acad. Sci. | pmid:2861776 |
| Vayer P et al. | Conversion of gamma-hydroxybutyrate to gamma-aminobutyrate in vitro. | 1985 | J. Neurochem. | pmid:2863327 |
| pmid:28644952 | ||||
| Scaduto RC and Schoolwerth AC | Effect of bicarbonate on glutamine and glutamate metabolism by rat kidney cortex mitochondria. | 1985 | Am. J. Physiol. | pmid:2864861 |
| Seren S et al. | Current-voltage relationships for proton flow through the F0 sector of the ATP-synthase, carbonylcyanide-p-trifluoromethoxyphenylhydrazone or leak pathways in submitochondrial particles. | 1985 | Eur. J. Biochem. | pmid:2865136 |
| Brown-Woodman PD et al. | Effects of malonic, maleic, citric and caffeic acids on the motility of human sperm and penetration of cervical mucus. | 1985 | Int. J. Fertil. | pmid:2867056 |
| Perez JA et al. | Characterisation of phosphate binding to mitochondrial and bacterial membrane-bound ATP synthase by studies of inhibition with 4-chloro-7-nitrobenzofurazan. | 1986 | FEBS Lett. | pmid:2869972 |
| Zoratti M et al. | ATP synthase-mediated proton fluxes and phosphorylation in rat liver mitochondria: dependence on delta mu H. | 1986 | Biochim. Biophys. Acta | pmid:2873837 |
| pmid:28777873 | ||||
| Koeppen AH and Riley KM | Effect of free malonate on the utilization of glutamate by rat brain mitochondria. | 1987 | J. Neurochem. | pmid:2881982 |
| Hall IH et al. | Inhibition of nucleic acid synthesis in P-388 lymphocytic leukemia cells in culture by sesquiterpene lactones. | 1988 Jan-Feb | Anticancer Res. | pmid:2895992 |
| pmid:29311556 | ||||
| Deb C et al. | Enhanced steroidogenesis in hen ovary after malonate administration. | 1979 | Endokrinologie | pmid:294958 |
| Woelders H et al. | The phosphate potential maintained by mitochondria in State 4 is proportional to the proton-motive force. | 1985 | FEBS Lett. | pmid:2981706 |
| Catia Sorgato M et al. | Partial uncoupling, or inhibition of electron transport rate, have equivalent effects on the relationship between the rate of ATP synthesis and proton-motive force in submitochondrial particles. | 1985 | FEBS Lett. | pmid:2982663 |
| Marzulli D et al. | N-ethylmaleimide as oxidizing agent in biological and non-biological systems. | 1985 | Boll. Soc. Ital. Biol. Sper. | pmid:2983741 |
| Vitorica J et al. | Impairment of glutamate uptake and absence of alterations in the energy-transducing ability of old rat brain mitochondria. | 1985 | Mech. Ageing Dev. | pmid:2985886 |
| Latipää PM et al. | Regulation of palmitoylcarnitine oxidation in isolated rat liver mitochondria. Role of the redox state of NAD(H). | 1986 | Biochim. Biophys. Acta | pmid:3002483 |
| Brown GC and Brand MD | Changes in permeability to protons and other cations at high proton motive force in rat liver mitochondria. | 1986 | Biochem. J. | pmid:3010957 |
| Beavis AD and Lehninger AL | The upper and lower limits of the mechanistic stoichiometry of mitochondrial oxidative phosphorylation. Stoichiometry of oxidative phosphorylation. | 1986 | Eur. J. Biochem. | pmid:3015613 |
| Chen M and Zhu QS | Rapid redox equilibrium between the mitochondrial Q pool and cytochrome b during triphasic reduction of cytochrome b by succinate. | 1986 | Biochim. Biophys. Acta | pmid:3019394 |
| Halestrap AP | Glucagon treatment of rats activates the respiratory chain of liver mitochondria at more than one site. | 1987 | Biochim. Biophys. Acta | pmid:3028493 |
| Fahien LA et al. | Regulation of insulin release by factors that also modify glutamate dehydrogenase. | 1988 | J. Biol. Chem. | pmid:3047128 |
| Schroyens WA et al. | Comparative effect of cisplatin, spiroplatin, carboplatin, iproplatin and JM40 in a human myeloid clonogenic assay. | 1988 | Eur J Cancer Clin Oncol | pmid:3053206 |
| Ingvorsen K et al. | Microbial hydrolysis of organic nitriles and amides. | 1988 | Ciba Found. Symp. | pmid:3073055 |
| Kim YS and Lee JK | Evidence that two covalent intermediates, phosphoryl and malonyl enzymes, are formed during malonyl-coenzyme A synthetase catalysis. | 1986 | J. Biol. Chem. | pmid:3097006 |
| Colombo G et al. | Characterization of highly purified dopamine beta-hydroxylase. | 1987 | Arch. Biochem. Biophys. | pmid:3101599 |
| Preuss HG et al. | Acidotic alterations in oxidative metabolism influencing rat renal slice ammoniagenesis. | 1987 | Life Sci. | pmid:3116359 |
| Strasser de Saad AM et al. | Malolactic enzyme in Lactobacillus murinus. | 1988 | Biochimie | pmid:3139053 |
| Pattarelli PP et al. | Oxidation of [U-14C]succinic semialdehyde in cultured human lymphoblasts: measurement of residual succinic semialdehyde dehydrogenase activity in 11 patients with 4-hydroxybutyric aciduria. | 1988 | Pediatr. Res. | pmid:3140205 |
| Worsham LM et al. | Chemical cross-linking and its effect on fatty acid synthetase activity in intact chloroplasts from Euglena gracilis. | 1988 | Biochim. Biophys. Acta | pmid:3143414 |
| Becker BF and Duhm J | Evidence for anionic cation transport of lithium, sodium and potassium across the human erythrocyte membrane induced by divalent anions. | 1978 | J. Physiol. (Lond.) | pmid:31458 |
| Tomson CR et al. | The effect of oxalate and malonate on red cell metabolism. | 1988 | Blood | pmid:3167215 |
| Vinogradov AD et al. | Studies on the succinate dehydrogenating system. I. Kinetics of the succinate dehydrogenase interaction with a semiquindiimine radical of N,N,N',N'-tetramethyl-p-phenylenediamine. | 1979 | Biochim. Biophys. Acta | pmid:31933 |
| Aoyama H et al. | Induction of lipid peroxidation in tissues of thallous malonate-treated hamster. | 1988 | Toxicology | pmid:3201472 |
| Raj RK et al. | Oxidative activities in mitochondria-like particles from Setaria digitata, a filarial parasite. | 1988 | Biochem. J. | pmid:3223930 |
| Boquist L et al. | Structural beta-cell changes and transient hyperglycemia in mice treated with compounds inducing inhibited citric acid cycle enzyme activity. | 1988 | Diabetes | pmid:3275558 |
| Begg AC et al. | Radiosensitization in vitro by cis-diammine (1,1-cyclobutanedicarboxylato) platinum(II) (carboplatin, JM8) and ethylenediammine-malonatoplatinum(II) (JM40). | 1987 | Radiother Oncol | pmid:3303163 |
| Lelieveld P et al. | Preclinical toxicology of platinum analogues in dogs. | 1987 | Eur J Cancer Clin Oncol | pmid:3308482 |
| van Hennik MB et al. | Comparative pharmacokinetics of cisplatin and three analogues in mice and humans. | 1987 | Cancer Res. | pmid:3315183 |
| Rigoulet M et al. | Redistribution of the flux-control coefficients in mitochondrial oxidative phosphorylations in the course of brain edema. | 1988 | Biochim. Biophys. Acta | pmid:3337798 |
| Kunz WS | Evaluation of electron-transfer flavoprotein and alpha-lipoamide dehydrogenase redox states by two-channel fluorimetry and its application to the investigation of beta-oxidation. | 1988 | Biochim. Biophys. Acta | pmid:3337800 |
| Stärk A et al. | Lentinellic acid, a biologically active protoilludane derivative from Lentinellus species (Basidiomycetes). | 1988 Mar-Apr | Z. Naturforsch., C, J. Biosci. | pmid:3388954 |
| Kim YS and Bang SK | Assays for malonyl-coenzyme A synthase. | 1988 | Anal. Biochem. | pmid:3389517 |
| Dewar MJ and Dieter KM | Mechanism of the chain extension step in the biosynthesis of fatty acids. | 1988 | Biochemistry | pmid:3390433 |
| Domingo JL et al. | Comparative effects of several chelating agents on the toxicity, distribution and excretion of aluminium. | 1988 | Hum Toxicol | pmid:3391623 |
| Belikova IuO and Kotliar AB | [Malate oxidation by mitochondrial succinate:ubiquinone-reductase]. | 1988 | Biokhimiia | pmid:3395646 |
| Mauldin SK et al. | Displacement of the bidentate malonate ligand from (d,l-trans-1,2-diaminocyclohexane)malonatoplatinum(II) by physiologically important compounds in vitro. | 1988 | Biochem. Pharmacol. | pmid:3401260 |
| Pollitt RJ et al. | Increased excretion of propan-1,3-diol and 3-hydroxypropionic acid apparently caused by abnormal bacterial metabolism in the gut. | 1987 | Clin. Chim. Acta | pmid:3427776 |
| Connors KA and Ifan A | Chromogenic reactions of tertiary amines with polycarboxylic acids and acetic anhydride: carbon suboxide as the reactive species in the malonic acid reagent. | 1987 | J Pharm Sci | pmid:3430350 |
| Schuster M et al. | Production of mycotoxins by Fusarium species isolated in Germany. 2. Time course of deoxynivalenol and 3-acetyldeoxynivalenol formation by Fusarium graminearum in different liquid media. | 1987 | Z Lebensm Unters Forsch | pmid:3439351 |
| Berthon G et al. | Histamine as a ligand in blood plasma. Part 7. Malate, malonate, maleate and tartrate as adjuvants of zinc to favour histamine tissue diffusion through mixed-ligand coordination. In vitro tests on lymphocyte proliferation. | 1987 | Agents Actions | pmid:3445819 |
| Carnieri EG et al. | The mechanism and biological role of calcium transport by plant mitochondria. | 1987 | Braz. J. Med. Biol. Res. | pmid:3452457 |
| Mohri T et al. | Differences of affinity and energetics of the active transport systems for amino acids in Chang liver cells. | 1979 | J. Biochem. | pmid:34597 |
| Kuch H | Clobazam: chemical aspects of the 1,4 and 1,5-benzodiazepines. | 1979 | Br J Clin Pharmacol | pmid:35199 |
| Boveris A et al. | Fumarate reductase and other mitochondrial activities in Trypanosoma cruzi. | 1986 | Mol. Biochem. Parasitol. | pmid:3523239 |
| Beavis AD | Upper and lower limits of the charge translocation stoichiometry of mitochondrial electron transport. | 1987 | J. Biol. Chem. | pmid:3571252 |
| Gripp S et al. | [Comparison between 2 methods of determining photon-induced air activity around medical accelerators]. | 1987 | Strahlenther Onkol | pmid:3603367 |
| Stoops JK et al. | Small-angle neutron-scattering and electron microscope studies of the chicken liver fatty acid synthase. | 1987 | J. Biol. Chem. | pmid:3611059 |
| Hajjawi OS and Hider RC | Malonate transport in human red blood cells. | 1987 | Mol. Cell. Biochem. | pmid:3627105 |
| Iwakura M et al. | Studies on regulatory functions of malic enzymes. VI. Purification and molecular properties of NADP-linked malic enzyme from Escherichia coli W. | 1979 | J. Biochem. | pmid:36376 |
| Anderson PM et al. | Interaction of mono- and dianions with cyanase: evidence for apparent half-site binding. | 1987 | Biochemistry | pmid:3651424 |
| Hori T and Okuyama H | Variation of oleate/cis-vaccenate ratios and its regulation by substrates in hepatic tissues. | 1987 | J. Biochem. | pmid:3654590 |
| Szewczyk A et al. | Purification by affinity chromatography of the dicarboxylate carrier from bovine heart mitochondria. | 1987 | Biochim. Biophys. Acta | pmid:3676300 |
| Le Minor L et al. | [Characterization of a 7th subspecies of Salmonella: S. choleraesuis subsp. indica subsp. nov]. | 1986 Sep-Oct | Ann. Inst. Pasteur Microbiol. | pmid:3689588 |
| Elferink F et al. | Pharmacokinetics of ethylenediaminemalonatoplatinum(II) (JM-40) during phase I trial. | 1987 | Br. J. Cancer | pmid:3689665 |
| Mauldin SK et al. | Effects of the bidentate malonate ligand on the utilization and cytotoxicity of platinum compounds in the L1210 cell line. | 1986 | Cancer Res. | pmid:3698013 |
| Escriva F et al. | Evidence that the development of hepatic fatty acid oxidation at birth in the rat is concomitant with an increased intramitochondrial CoA concentration. | 1986 | Eur. J. Biochem. | pmid:3699026 |