Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Vanag VK and Epstein IR Pattern formation in a tunable medium: the Belousov-Zhabotinsky reaction in an aerosol OT microemulsion. 2001 Phys. Rev. Lett. pmid:11736430
Míguez DG et al. Effect of axial growth on Turing pattern formation. 2006 Phys. Rev. Lett. pmid:16486904
Míguez DG et al. Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction. 2006 Phys. Rev. Lett. pmid:17155511
RULON O The experimental modification of developmental patterns in Arbacia with malonic acid. 1948 Physiol. Zool. pmid:18913650
RULON O The modification of developmental pattern in the sand dollar by malonic acid. 1951 Physiol. Zool. pmid:14807725
Muth D et al. Differentiation of isomeric malonylated flavonoid glyconjugates in plant extracts with UPLC-ESI/MS/MS. 2008 Sep-Oct Phytochem Anal pmid:18473328
Donna LD et al. Structural characterisation of malonyl flavonols in leek (Allium porrum L.) using high-performance liquid chromatography and mass spectrometry. Phytochem Anal pmid:24375682
Saito N et al. 7-Polyacylated delphinidin 3,7-diglucosides from the blue flowers of Leschenaultia cv. Violet Lena. 2007 Phytochemistry pmid:17174991
Tatsuzawa F et al. Triacylated cyanidin 3-(3X-glucosylsambubioside)-5-glucosides from the flowers of Malcolmia maritima. 2008 Phytochemistry pmid:17928016
Callahan DL et al. Elemental and metabolite profiling of nickel hyperaccumulators from New Caledonia. 2012 Phytochemistry pmid:22795763
Saito N et al. Tetra-acylated cyanidin 3-sophoroside-5-glucosides from the flowers of Iberis umbellata L. (Cruciferae). 2008 Phytochemistry pmid:18514755
Toki K et al. Anthocyanins from the scarlet flowers of Anemone coronaria. 2001 Phytochemistry pmid:11314957
Ermayanti TM et al. Stimulation of synthesis and release of swainosonine from transformed roots of Swainsona galegifolia. 1994 Phytochemistry pmid:7764877
Drewes SE et al. Antimicrobial monomeric and dimeric diterpenes from the leaves of Helichrysum tenax var tenax. 2006 Phytochemistry pmid:16434071
Nørbaek R et al. Anthocyanins from flowers of Cichorium intybus. 2002 Phytochemistry pmid:12031425
Saito N et al. Acylated anthocyanins from the blue-violet flowers of Anemone coronaria. 2002 Phytochemistry pmid:12031427
Bringmann G et al. Convergence in the biosynthesis of acetogenic natural products from plants, fungi, and bacteria. Phytochemistry pmid:19786287
Li J and Copeland L Role of malonate in chickpeas. 2000 Phytochemistry pmid:10963451
Liu Z et al. Hypoglycemic effects of malonyl-ginsenosides extracted from roots of Panax ginseng on streptozotocin-induced diabetic mice. 2009 Phytother Res pmid:19277974
Chen H et al. Malonyl-CoA synthetase, encoded by ACYL ACTIVATING ENZYME13, is essential for growth and development of Arabidopsis. 2011 Plant Cell pmid:21642549
Wang YY and Tsay YF Arabidopsis nitrate transporter NRT1.9 is important in phloem nitrate transport. 2011 Plant Cell pmid:21571952
Zhao J et al. MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. 2011 Plant Cell pmid:21467581
Fatland BL et al. Reverse genetic characterization of cytosolic acetyl-CoA generation by ATP-citrate lyase in Arabidopsis. 2005 Plant Cell pmid:15608338
Araújo WL et al. Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture. 2011 Plant Cell pmid:21307286
Laus MN et al. Plant inner membrane anion channel (PIMAC) function in plant mitochondria. 2008 Plant Cell Physiol. pmid:18511459
Sasaki T et al. Closing plant stomata requires a homolog of an aluminum-activated malate transporter. 2010 Plant Cell Physiol. pmid:20154005
Taniguchi Y et al. Differentiation of dicarboxylate transporters in mesophyll and bundle sheath chloroplasts of maize. 2004 Plant Cell Physiol. pmid:14988489
Iijima Y et al. Metabolite annotations based on the integration of mass spectral information. 2008 Plant J. pmid:18266924
Kovermann P et al. The Arabidopsis vacuolar malate channel is a member of the ALMT family. 2007 Plant J. pmid:18005230
Renné P et al. The Arabidopsis mutant dct is deficient in the plastidic glutamate/malate translocator DiT2. 2003 Plant J. pmid:12887583
Guan X and Nikolau BJ AAE13 encodes a dual-localized malonyl-CoA synthetase that is crucial for mitochondrial fatty acid biosynthesis. 2016 Plant J. pmid:26836315
Burke JJ et al. Succinate dehydrogenase : a partial purification from mung bean hypocotyls and soybean cotyledons. 1982 Plant Physiol. pmid:16662722
Chappell J and Beevers H Transport of dicarboxylic acids in castor bean mitochondria. 1983 Plant Physiol. pmid:16663021
Reibach PH and Streeter JG Metabolism of C-labeled photosynthate and distribution of enzymes of glucose metabolism in soybean nodules. 1983 Plant Physiol. pmid:16663058
Kennedy RA et al. Germination of Echinochloa crus-galli (Barnyard Grass) Seeds under Anaerobic Conditions : Respiration and Response to Metabolic Inhibitors. 1983 Plant Physiol. pmid:16663086
Davis LC and Nordin P Sugar and organic Acid constituents in white clover. 1983 Plant Physiol. pmid:16663119
Mukherjee KD Lipid biosynthesis in developing mustard seed: formation of triacylglycerols from endogenous and exogenous Fatty acids. 1983 Plant Physiol. pmid:16663345
Oliver DJ and Walker GH Characterization of the transport of oxaloacetate by pea leaf mitochondria. 1984 Plant Physiol. pmid:16663855
Rawsthorne S and Larue TA Metabolism under Microaerobic Conditions of Mitochondria from Cowpea Nodules. 1986 Plant Physiol. pmid:16664950
Streeter JG Carbohydrate, organic Acid, and amino Acid composition of bacteroids and cytosol from soybean nodules. 1987 Plant Physiol. pmid:16665774
Zoglowek C et al. Oxaloacetate and malate transport by plant mitochondria. 1988 Plant Physiol. pmid:16666083
Martins IS et al. Effect of the electrochemical proton gradient and anions on the ATPase activity of soybean submitochondrial particles. 1988 Plant Physiol. pmid:16666151
Kumar PA et al. Glycine supports in vivo reduction of nitrate in barley leaves. 1988 Plant Physiol. pmid:16666483
Tang X et al. Global gene profiling of laser-captured pollen mother cells indicates molecular pathways and gene subfamilies involved in rice meiosis. 2010 Plant Physiol. pmid:20959420
Taylor NL et al. Analysis of the rice mitochondrial carrier family reveals anaerobic accumulation of a basic amino acid carrier involved in arginine metabolism during seed germination. 2010 Plant Physiol. pmid:20720170
Wingenter K et al. Increased activity of the vacuolar monosaccharide transporter TMT1 alters cellular sugar partitioning, sugar signaling, and seed yield in Arabidopsis. 2010 Plant Physiol. pmid:20709831
Brooks CA et al. Salicylhydroxamic acid potentiates germination of 'Waldmann's Green' lettuce seed. 1985 Plant Physiol. pmid:11540836
George GM et al. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. 2010 Plant Physiol. pmid:20605913
Bräutigam A et al. An mRNA blueprint for C4 photosynthesis derived from comparative transcriptomics of closely related C3 and C4 species. 2011 Plant Physiol. pmid:20543093
Génard M and Gouble B ETHY. A theory of fruit climacteric ethylene emission. 2005 Plant Physiol. pmid:16143642
Hurth MA et al. Impaired pH homeostasis in Arabidopsis lacking the vacuolar dicarboxylate transporter and analysis of carboxylic acid transport across the tonoplast. 2005 Plant Physiol. pmid:15728336
Jeong J et al. A nodule-specific dicarboxylate transporter from alder is a member of the peptide transporter family. 2004 Plant Physiol. pmid:15001700
Dobritsa AA et al. LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis. 2010 Plant Physiol. pmid:20442277
Benedito VA et al. Genomic inventory and transcriptional analysis of Medicago truncatula transporters. 2010 Plant Physiol. pmid:20023147
Jacoby B and Laties GG Bicarbonate Fixation and Malate Compartmentation in Relation to Salt-induced Stoichiometric Synthesis of Organic Acid. 1971 Plant Physiol. pmid:16657654
Miller RJ and Koeppe DE The effect of calcium and inhibitors on corn mitochondrial respiration. 1971 Plant Physiol. pmid:16657714
Storey BT and Bahr JT The Respiratory Chain of Plant Mitochondria: XIV. Ordering of Ubiquinone, Flavoproteins, and Cytochromes in the Respiratory Chain. 1972 Plant Physiol. pmid:16658140
Iwata T and Stowe BB Probing a Membrane Matrix Regulating Hormone Action: II. The Kinetics of Lipid-Induced Growth and Ethylene Production. 1973 Plant Physiol. pmid:16658394
Jaworski JG and Kuć J Effect of Ethrel and Ceratocystis fimbriata on the Synthesis of Fatty Acids and 6-Methoxy Mellein in Carrot Root. 1974 Plant Physiol. pmid:16658701
Chapman EA and Graham D The effect of light on the tricarboxylic Acid cycle in green leaves: I. Relative rates of the cycle in the dark and the light. 1974 Plant Physiol. pmid:16658809
Chapman EA and Osmond CB The Effect of Light on the Tricarboxylic Acid Cycle in Green Leaves: III. A Comparison between Some C(3) and C(4) Plants. 1974 Plant Physiol. pmid:16658811
Tingwa PO and Young RE The effect of tonicity and metabolic inhibitors on respiration and ripening of avocado fruit slices. 1974 Plant Physiol. pmid:16658998
Kinraide TB and Behan MJ Restoration of Organic Acid Accumulation in Sectioned Leaves of Bryophyllum tubiflorum Harv. 1975 Plant Physiol. pmid:16659404
Muslih RK and Linscott DL Regulation of lipid synthesis in soybeans by two benzoic Acid herbicides. 1977 Plant Physiol. pmid:16660173
Willeford KO et al. Evidence for Chloroplastic Succinate Dehydrogenase Participating in the Chloroplastic Respiratory and Photosynthetic Electron Transport Chains of Chlamydomonas reinhardtii. 1989 Plant Physiol. pmid:16666855
Ngam-Ek A et al. Malate-Induced Hysteresis of Phosphoenolpyruvate Carboxylase from Crassula argentea. 1989 Plant Physiol. pmid:16667161
Bouzayen M et al. Carrier-Mediated Uptake of 1-(Malonylamino)cyclopropane-1-Carboxylic Acid in Vacuoles Isolated from Catharanthus roseus Cells. 1989 Plant Physiol. pmid:16667182
Chin CK and Lee M Effect of pH on the Activity of Some Respiratory Inhibitors. 1980 Plant Physiol. pmid:16661576
Stumpf DK and Burris RH Organic Acid contents of soybean: age and source of nitrogen. 1981 Plant Physiol. pmid:16662077
Stumpf DK and Burris RH Biosynthesis of malonate in roots of soybean seedlings. 1981 Plant Physiol. pmid:16662078
Duggan JX et al. Catabolism of 5-Aminolevulinic Acid to CO(2) by Etiolated Barley Leaves. 1982 Plant Physiol. pmid:16662156
Martins N et al. Changes on organic acid secretion and accumulation in Plantago almogravensis Franco and Plantago algarbiensis Samp. under aluminum stress. 2013 Plant Sci. pmid:23199681
Kim YS and Kim EJ A plasmid responsible for malonate assimilation in Pseudomonas fluorescens. 1994 Plasmid pmid:7846146
Hopwood DA Cracking the polyketide code. 2004 PLoS Biol. pmid:14966534
Chopra T et al. Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase. 2008 PLoS Biol. pmid:18613748
Orgel LE The implausibility of metabolic cycles on the prebiotic Earth. 2008 PLoS Biol. pmid:18215113
Levinson NM et al. A Src-like inactive conformation in the abl tyrosine kinase domain. 2006 PLoS Biol. pmid:16640460
Sprague ER et al. Crystal structure of the HSV-1 Fc receptor bound to Fc reveals a mechanism for antibody bipolar bridging. 2006 PLoS Biol. pmid:16646632
Gianchandani EP et al. Functional states of the genome-scale Escherichia coli transcriptional regulatory system. 2009 PLoS Comput. Biol. pmid:19503608
Bazil JN et al. Modeling mitochondrial bioenergetics with integrated volume dynamics. 2010 PLoS Comput. Biol. pmid:20052270
Bordel S et al. Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes. 2010 PLoS Comput. Biol. pmid:20657658
Holder JW et al. Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development. 2011 PLoS Genet. pmid:21931557
Jung KH et al. Identification and functional analysis of light-responsive unique genes and gene family members in rice. 2008 PLoS Genet. pmid:18725934
Taghavi S et al. Genome sequence of the plant growth promoting endophytic bacterium Enterobacter sp. 638. 2010 PLoS Genet. pmid:20485560
Letek M et al. The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions. 2010 PLoS Genet. pmid:20941392
Dunning Hotopp JC et al. Comparative genomics of emerging human ehrlichiosis agents. 2006 PLoS Genet. pmid:16482227
Saudemont A et al. Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. 2010 PLoS Genet. pmid:21203442
Gobert GN et al. Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes. 2010 PLoS Negl Trop Dis pmid:20161728
Wu J et al. Metabolic changes reveal the development of schistosomiasis in mice. 2010 PLoS Negl Trop Dis pmid:20824219
Karakikes I et al. Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. 2009 PLoS ONE pmid:19649297
Seifert EL et al. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. 2010 PLoS ONE pmid:20352092
Finley LW et al. Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. 2011 PLoS ONE pmid:21858060
Egea PF et al. Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus. 2008 PLoS ONE pmid:18953414
Lin H et al. The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. 2011 PLoS ONE pmid:21552483
Thomas B et al. Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. 2011 PLoS ONE pmid:21304957
Kubicek J et al. Controlled in meso phase crystallization--a method for the structural investigation of membrane proteins. 2012 PLoS ONE pmid:22536388
Kil DY et al. Age and diet affect gene expression profiles in canine liver tissue. 2010 PLoS ONE pmid:20967283
Zuno-Floriano FG et al. Effect of Acinetobacter sp on metalaxyl degradation and metabolite profile of potato seedlings (Solanum tuberosum L.) alpha variety. 2012 PLoS ONE pmid:22363586
Fujii T and Albarède F Ab initio calculation of the Zn isotope effect in phosphates, citrates, and malates and applications to plants and soil. 2012 PLoS ONE pmid:22363478
Wang N et al. Changes in soybean global gene expression after application of lipo-chitooligosaccharide from Bradyrhizobium japonicum under sub-optimal temperature. 2012 PLoS ONE pmid:22348109