| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Abscess | D000038 | 13 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Matern U et al. | Conformational changes of apigenin 7-O-(6-O-malonylglucoside), a vacuolar pigment from parsley, with solvent composition and proton concentration. | 1983 | Eur. J. Biochem. | pmid:6303788 |
| Bindoli A et al. | Mitochondrial lipid peroxidation by cumene hydroperoxide and its prevention by succinate. | 1982 | Biochim. Biophys. Acta | pmid:6289887 |
| Eriksson B et al. | Pyrophosphate analogues as inhibitors of herpes simplex virus type 1 DNA polymerase. | 1980 | Biochim. Biophys. Acta | pmid:6245699 |
| Malviya AN et al. | Observations on the oxidoreduction of the two cytochromes b in cytochrome c-deficient mitochondria and submitochondrial particles. | 1980 | Biochim. Biophys. Acta | pmid:6243963 |
| Costa LE et al. | Stoichiometry of mitochondrial H+ translocation coupled to succinate oxidation at level flow. | 1984 | J. Biol. Chem. | pmid:6232269 |
| Yamaguchi M et al. | Role of zinc as an activator of mitochondrial function in rat liver. | 1982 | Biochem. Pharmacol. | pmid:6212062 |
| Nakae Y and Shono M | Kinetic behaviour of succinate dehydrogenase of three fibre types in skeletal muscle. I. Effects of temperature and a competitive inhibitor. | 1984 | Histochem. J. | pmid:6210273 |
| Wingrove DE et al. | Glucagon effects on the membrane potential and calcium uptake rate of rat liver mitochondria. | 1984 | J. Biol. Chem. | pmid:6204980 |
| Calderon-Attas P et al. | In vitro effects of ethanol and ethanol metabolism in the rat pancreas. | 1980 | Biochim. Biophys. Acta | pmid:6165387 |
| Brown GK et al. | Malonyl coenzyme A decarboxylase deficiency. | 1984 | J. Inherit. Metab. Dis. | pmid:6145813 |
| Schoolwerth AC et al. | Glutamate transprot in rat kidney mitochondria. | 1983 | J. Biol. Chem. | pmid:6130095 |
| LaNoue KF et al. | Ammonia formation in isolated rat liver mitochondria. | 1983 | J. Biol. Chem. | pmid:6130094 |
| van der Kooij D et al. | Multiplication of fluorescent pseudomonads at low substrate concentrations in tap water. | 1982 | Antonie Van Leeuwenhoek | pmid:6127053 |
| Journet EP et al. | Glutamate metabolism triggered by oxaloacetate in intact plant mitochondria. | 1982 | Arch. Biochem. Biophys. | pmid:6123300 |
| Lindmark DG | Energy metabolism of the anaerobic protozoon Giardia lamblia. | 1980 | Mol. Biochem. Parasitol. | pmid:6108507 |
| Duszyński J et al. | Homeostasis of the protonmotive force in phosphorylating mitochondria. | 1984 | Biochim. Biophys. Acta | pmid:6095904 |
| Williams WL et al. | Indirect inactivation of rabbit reticulocyte initiation factor eIF-2 by helenalin and bis(helenalinyl) malonate. | 1984 | Biochemistry | pmid:6095903 |
| Huang EM et al. | Succinate potentiates the action of platelet agonists. | 1984 | Thromb. Res. | pmid:6095483 |
| Ksenzenko M et al. | Relationships between the effects of redox potential, alpha-thenoyltrifluoroacetone and malonate on O(2) and H2O2 generation by submitochondrial particles in the presence of succinate and antimycin. | 1984 | FEBS Lett. | pmid:6090204 |
| Tripathi P et al. | Investigation of effect of alpha-naphthylamine and beta-naphthylamine on organic acids formation of self-sustaining coacervates. | 1979 | Zentralbl Bakteriol Naturwiss | pmid:573037 |
| Hussa RO | Effects of antimicrotubule agents, potassium and inhibitors of energy production on hCG secretion. | 1979 | In Vitro | pmid:572336 |
| Sam CT | Effect of malonate and maleate on growth and brefeldin A formation in Curvularia lunata. | 1978 | Folia Microbiol. (Praha) | pmid:566696 |
| Quehenberger P | The influence of carbon dioxide, bicarbonate and other buffers on the potential of antimony microelectrodes. | 1977 | Pflugers Arch. | pmid:558586 |
| Klimek J et al. | The relationship between energy generation and cholesterol side-chain cleavage reaction in the mitochondria from human term placenta. | 1979 | Biochim. Biophys. Acta | pmid:549647 |
| Harris P | The interpretation of the distribution of radioactivity between carboxyl and alkyl carbon in fatty acids, following exposure to 14C-labelled acetate or malonate. | 1979 | J. Mol. Cell. Cardiol. | pmid:522139 |
| Narayanan N and Eapen J | Effect of malonate, succinate and glucose, in vivo, on the uptake of Cesium-137 by pigeon (Columba livia) muscles. | 1971 | J. Radiat. Res. | pmid:5150020 |
| Vanni P et al. | Studies on isocitrate lyase isolated from Lupinus cotyledons. | 1979 | Can. J. Biochem. | pmid:509354 |
| Khan A et al. | Atopic hypersensitivity to cis-dichlorodiammineplatinum(II) and other platinum complexes. | 1975 | Cancer Res. | pmid:50881 |
| Dey SK and Deb C | Effect of sodium malonate on ovarian dehydrogenases. A histochemical study. | 1972 | Anat Anz | pmid:5063563 |
| McDowell EM | Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. II. Effects of sodium malonate on proximal convoluted tubule. | 1972 | Am. J. Pathol. | pmid:5061663 |
| Dosch W | Rapid and direct gas chromatographic determination of oxalic acid in urine. | 1979 | Urol. Res. | pmid:505684 |
| Sluse FE et al. | Mechanism of the exchanges catalysed by the oxoglutarate translocatory of rat-heart mitochondria. Kinetics of the exchange reactions between 2-oxoglutarate, malate and malonate. | 1972 | Eur. J. Biochem. | pmid:5039837 |
| Rafalski A and Raczyñska-Bojanowska K | Synthesis of malonate and methylmalonate and the formation of polyene antibiotics. | 1972 | Acta Biochim. Pol. | pmid:5036391 |
| Dey SK et al. | Testicular dehydrogenases in toads after malonate treatment. | 1971 | Acta Histochem. | pmid:4998164 |
| Buck R et al. | [Degradation and biosynthesis of L-phenylalanine by chloridazon-degrading bacteria]. | 1979 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:488918 |
| Calderon P et al. | In vitro lipid metabolism in the rat pancreas. II. Effects of secretagogues on fatty acid metabolism, net lipolysis and ATP levels. | 1979 | Biochim. Biophys. Acta | pmid:486518 |
| von Nicolai H and Zilliken F | [Gas chromatographic determination of oxalic acid, malonic acid and succinic acid in biological material]. | 1974 | J. Chromatogr. | pmid:4836242 |
| Ross JA and Tweedy BG | Malonic acid conjugation by soil microorganisms of a pesticide-derived aniline moiety. | 1973 | Bull Environ Contam Toxicol | pmid:4755262 |
| Chatterjee S et al. | Studies on protein and nucleic acid contents of toad testes following administration of sodium malonate. | 1973 | Endocrinol. Jpn. | pmid:4740601 |
| Rae IC et al. | Utilization of iron gallate and other organic iron complexes by bacteria from water supplies. | 1973 | Appl Microbiol | pmid:4716725 |
| Thabrew MI et al. | The effect of malonate on succinate metabolism in the excised gill of Carcinus maenas. | 1973 | Comp. Biochem. Physiol., B | pmid:4709984 |
| Preuss HG et al. | Effects of glutamine deamination on glutamine deamidation in rat kidney slices. | 1973 | J. Clin. Invest. | pmid:4693645 |
| Dey SK et al. | Pentose phosphate pathway and steroidogenesis in the immature rat ovary after malonate treatment. | 1972 | Acta Endocrinol. | pmid:4677789 |
| Anthony C and Dunstan PM | A novel pathway for bacterial growth on malonate and beta-hydroxybutyrate. | 1972 | Biochem. J. | pmid:4655436 |
| Blazevic DJ et al. | Evaluation of the PathoTec "Rapid I-D System". | 1973 | Appl Microbiol | pmid:4588196 |
| Denisenko TV et al. | [Decarboxylation of malonyl-CoA and biosynthesis of mevalonic acid in rat liver]. | 1979 | Biokhimiia | pmid:454714 |
| Prahoveanu E et al. | The effect of malonate on succinic dehydrogenase (SDH) activity during the multiplication of influenza and herpes viruses in the embryonate hen egg. | 1974 | Rev Roum Virol | pmid:4465902 |
| Crompton M et al. | The transport of sulphate and sulphite in rat liver mitochondria. | 1974 | Biochem. J. | pmid:4441366 |
| Ninomiya K et al. | Phosphorus in organic synthesis. IX. On the mechanism of esterification of malonic acid half esters by diphenyl phosphorazidate. | 1974 | Chem. Pharm. Bull. | pmid:4430027 |
| Ninomiya K et al. | Amino acids and peptides. XII. Phosphorus in organic synthesis. VIII. Reaction of malonic acid half esters with diphenyl phosphorazidate. | 1974 | Chem. Pharm. Bull. | pmid:4422651 |
| Bergene R and Melo TB | Free radicals in malonic acid: a study of radical conformations at 77K and 295K by the ESR-technique. | 1972 | Biophysik | pmid:4346520 |
| Kupriyanov VV and Saks VA | The effect of succinate, malonate and fumarate on the phosphorylating system of the submitochondrial particles. | 1972 | FEBS Lett. | pmid:4263927 |
| Sorgato MC and Ferguson SJ | Variable proton conductance of submitochondrial particles. | 1979 | Biochemistry | pmid:42433 |
| McDowell EM | Light and electron microscopic studies of rat kidney after administration of inhibitors of the citric acid cycle in vivo. A morphological and histochemical study of the pars recta during malonate poisoning. | 1974 | Virchows Arch B Cell Pathol | pmid:4210043 |
| Koeppen AH et al. | Malonate metabolism in rat brain mitochondria. | 1974 | Biochemistry | pmid:4152381 |
| Saint-Macary M and Foucher B | Comparative partial purification of the active dicarboxylate transport system of rat liver, kidney and heart mitochondria. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4084286 |
| Dry IB and Wiskich JT | Inhibition of 2-oxoglutarate oxidation in plant mitochondria by pyruvate. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4084285 |
| Zoratti M and Petronilli V | Multiple relationships between rate of oxidative phosphorylation and delta microH in rat liver mitochondria. | 1985 | FEBS Lett. | pmid:4065342 |
| Bourke E et al. | Effects of inhibitors of the tricarboxylic acid cycle on glutamine utilization in the intact dog kidney. Renal glutamine utilization following TCA cycle blockade. | 1985 | Contrib Nephrol | pmid:4064698 |
| Andrews PA et al. | Differential potentiation of alkylating and platinating agent cytotoxicity in human ovarian carcinoma cells by glutathione depletion. | 1985 | Cancer Res. | pmid:4063975 |
| Ullrich KJ et al. | Contraluminal sulfate transport in the proximal tubule of the rat kidney. III. Specificity: disulfonates, di- and tri-carboxylates and sulfocarboxylates. | 1985 | Pflugers Arch. | pmid:4059021 |
| Mikkelsen J et al. | Stoichiometry of substrate binding to rat liver fatty acid synthetase. | 1985 | Biochem. J. | pmid:4052054 |
| Kaplan RS and Pedersen PL | Isolation and reconstitution of the n-butylmalonate-sensitive dicarboxylate transporter from rat liver mitochondria. | 1985 | J. Biol. Chem. | pmid:4019514 |
| Svanas GW and Weiner H | Enzymatic requirement for cyanamide inactivation of rat liver aldehyde dehydrogenase. | 1985 | Biochem. Pharmacol. | pmid:3994742 |
| Ferchichi M et al. | Production of methanethiol from methionine by Brevibacterium linens CNRZ 918. | 1985 | J. Gen. Microbiol. | pmid:3989511 |
| Zell A et al. | Model for calcium binding to gamma-carboxyglutamic acid residues of proteins: crystal structure of calcium alpha-ethylmalonate. | 1985 | Biochemistry | pmid:3978091 |
| Winograd B et al. | Phase I study of ethylenediamine platinum(II) malonate (NSC 146 068), a second generation platinum analogue. | 1986 | Cancer Res. | pmid:3948186 |
| GarcÃa Sabater JF et al. | Taxonomic position of Klebsiella atlantae and Klebsiella edwardsii. | 1979 | J Hyg Epidemiol Microbiol Immunol | pmid:393774 |
| Stefancich G et al. | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-quinoline-3-carb oxylic acid, a new fluorinated compounds of oxacin family with high broad-spectrum antibacterial activities. | 1985 | Farmaco Sci | pmid:3926533 |
| Kim YS and Bang SK | Malonyl coenzyme A synthetase. Purification and properties. | 1985 | J. Biol. Chem. | pmid:3921541 |
| Affranchino JL and Stoppani AO | [Existence of 2 sites of oxidative phosphorylation in Trypanosoma cruzi]. | 1985 | Rev. Argent. Microbiol. | pmid:3916670 |
| Krausse R and Ullmann U | Studies on the identification of Campylobacter species using biochemical tests and high-performance liquid chromatography. | 1985 | Zentralbl Bakteriol Mikrobiol Hyg A | pmid:3911663 |
| Affranchino JL et al. | Respiratory control in mitochondria from Trypanosoma cruzi. | 1985 | Mol. Biochem. Parasitol. | pmid:3903495 |
| Nefelova MV et al. | [Nonactin biosynthesis. The incorporation of precursors into the antibiotic molecule]. | 1985 | Antibiot. Med. Biotekhnol. | pmid:3840667 |
| Packard AB et al. | The development of an 191Os----191mIr generator using an osmium chelate parent complex--I. Trans-dioxobismalonatoosmate(VI). | 1986 | Int J Rad Appl Instrum B | pmid:3818315 |
| Aoyama H et al. | Acute poisoning by intentional ingestion of thallous malonate. | 1986 | Hum Toxicol | pmid:3804358 |
| Søgaard P and Kjaeldgaard P | Two isolations of enteric group 69 from human clinical specimens. | 1986 | Acta Pathol Microbiol Immunol Scand B | pmid:3788575 |
| Bernard M et al. | [Azoles. 17. Beta-(4-pyrazol)acrylic and propionic acids and their anti-inflammatory activity]. | 1986 | Pharmazie | pmid:3786374 |
| Boquist L and Alehagen U | Ca2+ transport in isolated mouse liver mitochondria; role of reductive carboxylation and citrate? | 1986 | Cell Calcium | pmid:3768942 |
| Giurov B | [Biochemical characteristics of the causative agent of fowl typhoid]. | 1986 | Vet Med Nauki | pmid:3765371 |
| Nakae Y and Shono M | Histochemical modification of the active site of succinate dehydrogenase with N-acetylimidazole. | 1986 | Histochem. J. | pmid:3733466 |
| Gaziev GM and Baturo AP | [Characteristics of Klebsiella strains isolated from patients with acute intestinal diseases]. | 1986 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:3727877 |
| Hederstedt L and Hatefi Y | Modification of bovine heart succinate dehydrogenase with ethoxyformic anhydride and rose bengal: evidence for essential histidyl residues protectable by substrates. | 1986 | Arch. Biochem. Biophys. | pmid:3717948 |
| Sasaki T et al. | A novel macrolide antibiotic, notonesomycin A. | 1986 | J. Antibiot. | pmid:3710911 |
| Brezis M et al. | Mitochondrial activity: a possible determinant of anoxic injury in renal medulla. | 1986 | Experientia | pmid:3709765 |
| Haan EA et al. | Malonyl coenzyme A decarboxylase deficiency. Clinical and biochemical findings in a second child with a more severe enzyme defect. | 1986 | Eur. J. Pediatr. | pmid:3709568 |
| Escriva F et al. | Evidence that the development of hepatic fatty acid oxidation at birth in the rat is concomitant with an increased intramitochondrial CoA concentration. | 1986 | Eur. J. Biochem. | pmid:3699026 |
| Mauldin SK et al. | Effects of the bidentate malonate ligand on the utilization and cytotoxicity of platinum compounds in the L1210 cell line. | 1986 | Cancer Res. | pmid:3698013 |
| Elferink F et al. | Pharmacokinetics of ethylenediaminemalonatoplatinum(II) (JM-40) during phase I trial. | 1987 | Br. J. Cancer | pmid:3689665 |
| Le Minor L et al. | [Characterization of a 7th subspecies of Salmonella: S. choleraesuis subsp. indica subsp. nov]. | 1986 Sep-Oct | Ann. Inst. Pasteur Microbiol. | pmid:3689588 |
| Szewczyk A et al. | Purification by affinity chromatography of the dicarboxylate carrier from bovine heart mitochondria. | 1987 | Biochim. Biophys. Acta | pmid:3676300 |
| Hori T and Okuyama H | Variation of oleate/cis-vaccenate ratios and its regulation by substrates in hepatic tissues. | 1987 | J. Biochem. | pmid:3654590 |
| Anderson PM et al. | Interaction of mono- and dianions with cyanase: evidence for apparent half-site binding. | 1987 | Biochemistry | pmid:3651424 |
| Iwakura M et al. | Studies on regulatory functions of malic enzymes. VI. Purification and molecular properties of NADP-linked malic enzyme from Escherichia coli W. | 1979 | J. Biochem. | pmid:36376 |
| Hajjawi OS and Hider RC | Malonate transport in human red blood cells. | 1987 | Mol. Cell. Biochem. | pmid:3627105 |
| Stoops JK et al. | Small-angle neutron-scattering and electron microscope studies of the chicken liver fatty acid synthase. | 1987 | J. Biol. Chem. | pmid:3611059 |
| Gripp S et al. | [Comparison between 2 methods of determining photon-induced air activity around medical accelerators]. | 1987 | Strahlenther Onkol | pmid:3603367 |
| Beavis AD | Upper and lower limits of the charge translocation stoichiometry of mitochondrial electron transport. | 1987 | J. Biol. Chem. | pmid:3571252 |
| Boveris A et al. | Fumarate reductase and other mitochondrial activities in Trypanosoma cruzi. | 1986 | Mol. Biochem. Parasitol. | pmid:3523239 |
| Kuch H | Clobazam: chemical aspects of the 1,4 and 1,5-benzodiazepines. | 1979 | Br J Clin Pharmacol | pmid:35199 |