Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

Download all related citations
Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Ivanova N et al. Complete genome sequence of Gordonia bronchialis type strain (3410). 2010 Stand Genomic Sci pmid:21304674
Müller BA and Dhalla NS Mechanisms of the beneficial actions of ischemic preconditioning on subcellular remodeling in ischemic-reperfused heart. 2010 Curr Cardiol Rev pmid:22043201
Seifert EL et al. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. 2010 PLoS ONE pmid:20352092
Furutachi M et al. A heterobimetallic Ni/La-salan complex for catalytic asymmetric decarboxylative 1,4-addition of malonic acid half-thioester. 2010 Chem Asian J pmid:20839279
Wu N et al. Taurine prevents free fatty acid-induced hepatic insulin resistance in association with inhibiting JNK1 activation and improving insulin signaling in vivo. 2010 Diabetes Res. Clin. Pract. pmid:20855122
Mao Z et al. Water-compatible iminium activation: highly enantioselective organocatalytic Michael addition of malonates to α,β-unsaturated enones. 2010 J. Org. Chem. pmid:20936828
Bujacz G et al. Cryoprotection properties of salts of organic acids: a case study for a tetragonal crystal of HEW lysozyme. 2010 Acta Crystallogr. D Biol. Crystallogr. pmid:20606259
Wang YQ et al. Diverse manganese(II) coordination polymers with mixed azide and zwitterionic dicarboxylate ligands: structure and magnetic properties. 2010 Inorg Chem pmid:20095647
Kissen R et al. Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. 2010 BMC Genomics pmid:20307264
Hara Y et al. Molecular design and functional control of novel self-oscillating polymers. 2010 Int J Mol Sci pmid:20386662
Connor SC et al. Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. 2010 Mol Biosyst pmid:20567778
Calkins MJ et al. Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition. 2010 Toxicol. Sci. pmid:20211941
Lail K et al. Complete genome sequence of Spirosoma linguale type strain (1). 2010 Stand Genomic Sci pmid:21304700
Liu B et al. Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation. 2010 Mol. Cell. Biochem. pmid:19851835
Wang Z et al. Photochemical cycling of iron mediated by dicarboxylates: special effect of malonate. 2010 Environ. Sci. Technol. pmid:20000366
Chen AM et al. Identification of a TRAP transporter for malonate transport and its expression regulated by GtrA from Sinorhizobium meliloti. 2010 Res. Microbiol. pmid:20594941
Kokubo K et al. Synthesis and regiochemistry of [60]fullerenyl 2-methylmalonate bisadducts and their facile electron-accepting properties. 2010 J. Org. Chem. pmid:20524640
Furrow SD and Aurentz DJ Reactions of iodomalonic acid, diiodomalonic acid, and other organics in the Briggs-Rauscher oscillating system. 2010 J Phys Chem A pmid:20121222
Uemura T et al. Unveiling thermal transitions of polymers in subnanometre pores. 2010 Nat Commun pmid:20981011
Kil DY et al. Age and diet affect gene expression profiles in canine liver tissue. 2010 PLoS ONE pmid:20967283
Tang X et al. Global gene profiling of laser-captured pollen mother cells indicates molecular pathways and gene subfamilies involved in rice meiosis. 2010 Plant Physiol. pmid:20959420
Frank S Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease. 2010 Neuropsychiatr Dis Treat pmid:20957126
Dieng PS and Sirlin C Recognition of chiral carboxylic anions by artificial receptors. 2010 Int J Mol Sci pmid:20957098
Shi T et al. cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. 2010 PLoS ONE pmid:20957031
Wise JK et al. Temporal gene expression profiling during rat femoral marrow ablation-induced intramembranous bone regeneration. 2010 PLoS ONE pmid:20957030
de Lucena DK et al. The role of sigma factor RpoH1 in the pH stress response of Sinorhizobium meliloti. 2010 BMC Microbiol. pmid:20955556
Pradhan RK et al. Characterization of membrane potential dependency of mitochondrial Ca2+ uptake by an improved biophysical model of mitochondrial Ca2+ uniporter. 2010 PLoS ONE pmid:20949039
Christie-Oleza JA and Armengaud J In-depth analysis of exoproteomes from marine bacteria by shotgun liquid chromatography-tandem mass spectrometry: the Ruegeria pomeroyi DSS-3 case-study. 2010 Mar Drugs pmid:20948905
Axelrod HL et al. Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris. 2010 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:20944231
Letek M et al. The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions. 2010 PLoS Genet. pmid:20941392
Vermeulen RC et al. Patients with chronic fatigue syndrome performed worse than controls in a controlled repeated exercise study despite a normal oxidative phosphorylation capacity. 2010 J Transl Med pmid:20937116
Hanin A et al. Screening of in vivo activated genes in Enterococcus faecalis during insect and mouse infections and growth in urine. 2010 PLoS ONE pmid:20686694
Balk M et al. (Per)chlorate reduction by an acetogenic bacterium, Sporomusa sp., isolated from an underground gas storage. 2010 Appl. Microbiol. Biotechnol. pmid:20680263
Hagos Y and Wolff NA Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity. 2010 Toxins (Basel) pmid:22069672
Bordel S et al. Sampling the solution space in genome-scale metabolic networks reveals transcriptional regulation in key enzymes. 2010 PLoS Comput. Biol. pmid:20657658
Chakraborty B et al. Stage specific developmental changes in the mitochondrial and surface membrane associated redox systems of Leishmania donovani promastigote and amastigote. 2010 Biochemistry Mosc. pmid:20618140
George GM et al. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. 2010 Plant Physiol. pmid:20605913
Blum Y et al. A factor model to analyze heterogeneity in gene expression. 2010 BMC Bioinformatics pmid:20598132
Gawarammana I et al. Fructose-1, 6-diphosphate (FDP) as a novel antidote for yellow oleander-induced cardiac toxicity: a randomized controlled double blind study. 2010 BMC Emerg Med pmid:20587052
Hullatti KK and Sharada MS Comparative phytochemical investigation of the sources of ayurvedic drug patha: a chromatographic fingerprinting analysis. 2010 Indian J Pharm Sci pmid:20582188
Rellán-Alvarez R et al. Changes in the proteomic and metabolic profiles of Beta vulgaris root tips in response to iron deficiency and resupply. 2010 BMC Plant Biol. pmid:20565974
Granjon T et al. Structure-function relations in oxaloacetate decarboxylase complex. Fluorescence and infrared approaches to monitor oxomalonate and Na(+) binding effect. 2010 PLoS ONE pmid:20543879
Kamga CK et al. Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria. 2010 Am. J. Physiol., Cell Physiol. pmid:20538765
Gauniya A et al. Comparative bioavailability studies of citric acid and malonic acid based aspirin effervescent tablets. 2010 J Pharm Bioallied Sci pmid:21814444
Dolezal P et al. The essentials of protein import in the degenerate mitochondrion of Entamoeba histolytica. 2010 PLoS Pathog. pmid:20333239
Xu H et al. Behavioral and neurobiological changes in C57BL/6 mouse exposed to cuprizone: effects of antipsychotics. 2010 Front Behav Neurosci pmid:20305752
Ruhaak LR et al. Glycan labeling strategies and their use in identification and quantification. 2010 Anal Bioanal Chem pmid:20225063
Caligiani A et al. 1H NMR fingerprinting of soybean extracts, with emphasis on identification and quantification of isoflavones. 2010 Nutrients pmid:22254020
Gonzalvez F et al. Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin. 2010 PLoS ONE pmid:20179769
Raymond F et al. Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue. 2010 BMC Genomics pmid:20175888
Zhao JS et al. Shewanella spp. genomic evolution for a cold marine lifestyle and in-situ explosive biodegradation. 2010 PLoS ONE pmid:20174598
Wu TY et al. Synthesis and characterization of organic dyes containing various donors and acceptors. 2010 Int J Mol Sci pmid:20162019
Maeda S et al. Active polymer gel actuators. 2010 Int J Mol Sci pmid:20162001
Gobert GN et al. Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes. 2010 PLoS Negl Trop Dis pmid:20161728
Sasaki T et al. Closing plant stomata requires a homolog of an aluminum-activated malate transporter. 2010 Plant Cell Physiol. pmid:20154005
Wang YH et al. Diastereoselective gamma-vinyl butyrolactone synthesis via gold catalyzed cyclization of allylic acetate. 2010 Chem. Commun. (Camb.) pmid:20062867
Smejkalová H et al. Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation. 2010 PLoS ONE pmid:20957036
Zeng WL 5-(4-Hy-droxy-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588666
Quah CK et al. 8-Hy-droxy-quinolinium 2-carb-oxy-acetate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588617
Aiyub Z et al. Tetra-μ-acetato-κO:O'-bis-[(N-ethyl-pyrimidin-2-amine)-copper(II)](Cu-Cu). 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588567
Wu DH and Wu QQ 4-Ethyl-anilinium 2-carb-oxy-acetate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588444
Meskini I et al. Diethyl 2-[(3,5-dimethyl-1H-pyrazol-1-yl)(4-meth-oxy-phen-yl)meth-yl]propane-dioate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588286
Xie HZ and Zhang YG μ-Adipato-bis-[chlorido(2,2':6',2''-terpyridine)-copper(II)] tetra-hydrate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588166
Eshtiagh-Hosseini H et al. catena-Poly[diacridinium [zinc(II)-di-μ-pyrazine-2,3-dicarboxyl-ato-κN,O:O;O:N,O]]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588129
Hu DY 4-(2-Carb-oxy-vin-yl)pyridinium iodide. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21587868
Subashini R et al. 2,4-Dichloro-7,8-dimethyl-quinoline. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21587784
Eshtiagh-Hosseini H et al. Bis(2-amino-4-methyl-pyridinium) trans-diaqua-bis-(pyrazine-2,3-dicarboxyl-ato)cuprate(II) hexa-hydrate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21587740
Duez S et al. Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues. 2010 Bioorg. Med. Chem. pmid:20036564
Qiu LF et al. catena-Poly[[(2,9-dimethyl-1,10-phenanthroline-κN,N')cobalt(II)]-μ-malonato-κO,O:O,O]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21587459
Meskini I et al. Diethyl 2-{(dibenzyl-amino)[4-(trifluoro-meth-yl)phen-yl]meth-yl}malonate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21580764
Meskini I et al. Diethyl 2-[(N-benzyl-N-methyl-amino)(phen-yl)meth-yl]propane-dioate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21580591
Liu HT et al. Poly[[diaqua-(μ(4)-l-tartrato)(μ(2)-l-tartrato)dizinc(II)] tetra-hydrate]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21580485
Shi ZF et al. Triaqua-(1,10-phenanthroline-2,9-dicarboxyl-ato)cobalt(II) dihydrate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21580484
Stevens P and van Elsas JD Genetic and phenotypic diversity of Ralstonia solanacearum biovar 2 strains obtained from Dutch waterways. 2010 Antonie Van Leeuwenhoek pmid:19960250
Vieira N et al. Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicans. 2010 Mol. Microbiol. pmid:19968788
Saudemont A et al. Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. 2010 PLoS Genet. pmid:21203442
Cohen A et al. From the Gla domain to a novel small-molecule detector of apoptosis. 2009 Cell Res. pmid:19223854
Feliciano I et al. Water-soluble molybdenocene complexes with both proliferative and antiproliferative effects on cancer cell lines and their binding interactions with human serum albumin. 2009 J. Biol. Inorg. Chem. pmid:19536567
Gianchandani EP et al. Functional states of the genome-scale Escherichia coli transcriptional regulatory system. 2009 PLoS Comput. Biol. pmid:19503608
Mallajosyula JK et al. Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease. 2009 Neurotox Res pmid:19526285
Tang LM et al. catena-Poly[[diaquacobalt(II)]-bis(μ-3-carboxy-adamantane-1-carboxyl-ato-κO:O)]. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21582328
Subashini R et al. 2,4-Dichloro-6-methoxy-quinoline. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21581968
Yang SX et al. catena-Poly[[aqua-trimethyl-tin(IV)]-{[trimethyl-tin(IV)]-μ(3)-thio-phene-2,5-dicarboxyl-ato}]. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21581753
Shi H 4-(4-Chloro-phen-yl)-7,7-dimethyl-7,8-dihydro-4H-1-benzopyran-2,5(3H,6H)-dione. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21580158
Strieter ER et al. Cascade reactions during coronafacic acid biosynthesis: elongation, cyclization, and functionalization during Cfa7-catalyzed condensation. 2009 J. Am. Chem. Soc. pmid:19199623
Seno K et al. Determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine. 2009 Anal Sci pmid:19276596
Grimberg H et al. Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. 2009 Apoptosis pmid:19172398
Miglio G et al. PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss. 2009 Neurochem. Int. pmid:19442697
Duan S et al. Lewis acid-catalyzed diastereoselective hydroarylation of benzylidene malonic esters. 2009 J. Org. Chem. pmid:19518152
Morrison HG et al. Characterization of thermal behavior of deep eutectic solvents and their potential as drug solubilization vehicles. 2009 Int J Pharm pmid:19477257
Su KL et al. Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme. 2009 Bioorg. Med. Chem. pmid:19595601
Yang L et al. Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. 2009 PLoS ONE pmid:19484125
Yadav AV et al. Co-crystals: a novel approach to modify physicochemical properties of active pharmaceutical ingredients. 2009 Indian J Pharm Sci pmid:20502540
Tonouchi A Isolation and characterization of a novel facultative anaerobic filamentous fungus from Japanese rice field soil. 2009 Int J Microbiol pmid:20148171
Foret J et al. Synthesis and evaluation of non-hydrolyzable D-mannose 6-phosphate surrogates reveal 6-deoxy-6-dicarboxymethyl-D-mannose as a new strong inhibitor of phosphomannose isomerases. 2009 Bioorg. Med. Chem. pmid:19783448
Baldwin A et al. Multilocus sequence typing of Cronobacter sakazakii and Cronobacter malonaticus reveals stable clonal structures with clinical significance which do not correlate with biotypes. 2009 BMC Microbiol. pmid:19852808
Kozjak-Pavlovic V et al. Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis. 2009 PLoS Pathog. pmid:19851451
Strickler MA et al. Functional characterization of a Na(+)-coupled dicarboxylate transporter from Bacillus licheniformis. 2009 Biochim. Biophys. Acta pmid:19840771
Goldstein P et al. Clustering of protein domains for functional and evolutionary studies. 2009 BMC Bioinformatics pmid:19832975
Niimi M et al. Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. 2009 J. Biomed. Sci. pmid:19825180