| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Abscess | D000038 | 13 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Salinero KK et al. | Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation. | 2009 | BMC Genomics | pmid:19650930 |
| Karakikes I et al. | Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a. | 2009 | PLoS ONE | pmid:19649297 |
| Wong HR et al. | Identification of pediatric septic shock subclasses based on genome-wide expression profiling. | 2009 | BMC Med | pmid:19624809 |
| Gu J et al. | Genomic and systems evolution in Vibrionaceae species. | 2009 | BMC Genomics | pmid:19594870 |
| Vaughan AM et al. | Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. | 2009 | Cell. Microbiol. | pmid:19068099 |
| Brown AK et al. | Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. | 2009 | PLoS ONE | pmid:19609444 |
| Casale A et al. | Sequestration of Alkyltin(IV) compounds in aqueous solution: formation, stability, and empirical relationships for the binding of dimethyltin(IV) cation by N- and O-donor ligands. | 2009 | Bioinorg Chem Appl | pmid:19590597 |
| Cohen A et al. | From the Gla domain to a novel small-molecule detector of apoptosis. | 2009 | Cell Res. | pmid:19223854 |
| Pistollato F et al. | Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells. | 2009 | PLoS ONE | pmid:19587783 |
| Seppet E et al. | Mitochondria and energetic depression in cell pathophysiology. | 2009 | Int J Mol Sci | pmid:19564950 |
| Bryan CG et al. | Carbon and arsenic metabolism in Thiomonas strains: differences revealed diverse adaptation processes. | 2009 | BMC Microbiol. | pmid:19549320 |
| Kumasaka T et al. | Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase. | 2009 | J. Biol. Chem. | pmid:19546224 |
| Parker N et al. | Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2. | 2009 | Biochim. Biophys. Acta | pmid:19539600 |
| Garcia-Ortiz JE et al. | Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. | 2009 | BMC Dev. Biol. | pmid:19538736 |
| Feliciano I et al. | Water-soluble molybdenocene complexes with both proliferative and antiproliferative effects on cancer cell lines and their binding interactions with human serum albumin. | 2009 | J. Biol. Inorg. Chem. | pmid:19536567 |
| Gianchandani EP et al. | Functional states of the genome-scale Escherichia coli transcriptional regulatory system. | 2009 | PLoS Comput. Biol. | pmid:19503608 |
| Amador P et al. | Resistance to β-lactams in bacteria isolated from different types of Portuguese cheese. | 2009 | Int J Mol Sci | pmid:19468324 |
| ZÃková A et al. | The F(0)F(1)-ATP synthase complex contains novel subunits and is essential for procyclic Trypanosoma brucei. | 2009 | PLoS Pathog. | pmid:19436713 |
| Kurakin A | Scale-free flow of life: on the biology, economics, and physics of the cell. | 2009 | Theor Biol Med Model | pmid:19416527 |
| Verma SK et al. | Structure of N-acetylglucosamine-1-phosphate uridyltransferase (GlmU) from Mycobacterium tuberculosis in a cubic space group. | 2009 | Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. | pmid:19407371 |
| Mallajosyula JK et al. | Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease. | 2009 | Neurotox Res | pmid:19526285 |
| Cheng YQ et al. | Type I polyketide synthases that require discrete acyltransferases. | 2009 | Meth. Enzymol. | pmid:19362640 |
| Argiriadi MA et al. | Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study. | 2009 | BMC Struct. Biol. | pmid:19296855 |
| Jørgensen TR et al. | Transcriptomic comparison of Aspergillus niger growing on two different sugars reveals coordinated regulation of the secretory pathway. | 2009 | BMC Genomics | pmid:19166577 |
| Tiziani S et al. | Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. | 2009 | PLoS ONE | pmid:19158949 |
| Zipse H et al. | Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. | 2009 | J. Am. Chem. Soc. | pmid:19128178 |
| Tran QT et al. | Chemical genomics of cancer chemopreventive dithiolethiones. | 2009 | Carcinogenesis | pmid:19126641 |
| Elliott JM et al. | Crystal structure of procaspase-1 zymogen domain reveals insight into inflammatory caspase autoactivation. | 2009 | J. Biol. Chem. | pmid:19117953 |
| Zeng WL et al. | 3-[(5-Methyl-furan-2-yl)methyl-ene]-1,5-dioxaspiro-[5.5]undecane-2,4-dione. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583701 |
| Zeng WL and Jian FF | 3-(2-Furylmethyl-ene)-1,5-dioxaspiro-[5.5]undecane-2,4-dione. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583569 |
| Soleimannejad J et al. | Poly[μ(2)-aqua-aqua-μ(4)-pyridine-2,4-dicarboxyl-ato-strontium]. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583378 |
| Liang WX et al. | Oxonium 2-carb-oxy-3-(2-fur-yl)acrylate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583167 |
| Li XZ et al. | 2-Carb-oxy-1-phenyl-ethanaminium perchlorate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583083 |
| Yan HY et al. | Aqua-(propane-dioato-κO,O)[2-(1H-pyrazol-1-yl-κN)-1,10-phenanthroline-κN,N']nickel(II) trihydrate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583013 |
| Tang LM et al. | catena-Poly[[diaquacobalt(II)]-bis(μ-3-carboxy-adamantane-1-carboxyl-ato-κO:O)]. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21582328 |
| Subashini R et al. | 2,4-Dichloro-6-methoxy-quinoline. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21581968 |
| Yang SX et al. | catena-Poly[[aqua-trimethyl-tin(IV)]-{[trimethyl-tin(IV)]-μ(3)-thio-phene-2,5-dicarboxyl-ato}]. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21581753 |
| Shi H | 4-(4-Chloro-phen-yl)-7,7-dimethyl-7,8-dihydro-4H-1-benzopyran-2,5(3H,6H)-dione. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21580158 |
| Liang WX et al. | 2-Carb-oxy-1-(3-nitro-phen-yl)ethanaminium perchlorate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21580006 |
| Feng S | Poly[hexa-aqua-bis(μ(3)-terephthalato)(μ(2)-terephthalato)diytterbium(III)]. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579932 |
| Zhang LY | catena-Poly[[diaquazinc(II)]-μ(3)-2,2'-dihydr-oxy-1,1'-binaphthyl-3,3'-di-carboxyl-ato-κO:O':O'']. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579924 |
| Lin JL and Xu W | μ-Succinato-κO:O-bis[(2,2'-bipyridine-κN,N')copper(II)] succinate dodeca-hydrate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21578149 |
| Strieter ER et al. | Cascade reactions during coronafacic acid biosynthesis: elongation, cyclization, and functionalization during Cfa7-catalyzed condensation. | 2009 | J. Am. Chem. Soc. | pmid:19199623 |
| Seno K et al. | Determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine. | 2009 | Anal Sci | pmid:19276596 |
| Grimberg H et al. | Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. | 2009 | Apoptosis | pmid:19172398 |
| Nam KH et al. | Insight into the antibacterial drug design and architectural mechanism of peptide recognition from the E. faecium peptide deformylase structure. | 2009 | Proteins | pmid:18831047 |
| Xie Z et al. | Modules of co-regulated metabolites in turmeric (Curcuma longa) rhizome suggest the existence of biosynthetic modules in plant specialized metabolism. | 2009 | J. Exp. Bot. | pmid:19073964 |
| Innocenti A et al. | Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates. | 2009 | Bioorg. Med. Chem. | pmid:19297172 |
| Hoffman DL and Brookes PS | Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions. | 2009 | J. Biol. Chem. | pmid:19366681 |
| Burow LC et al. | Anaerobic central metabolic pathways active during polyhydroxyalkanoate production in uncultured cluster 1 Defluviicoccus enriched in activated sludge communities. | 2009 | FEMS Microbiol. Lett. | pmid:19622073 |
| Choudhury SR et al. | Robust recognition of malonate and 2-amino-4-picolinium in conjunction with M(II) as a triad (M = Ni/Co/Mn): role of this highly stable hydrogen-bonded motif in driving supramolecular self-assembly. | 2009 | Dalton Trans | pmid:19759933 |
| Okrasa K et al. | Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19739187 |
| Hassan HA et al. | 1-Malonyl-1,4-dihydropyridine as a novel carrier for specific delivery of drugs to the brain. | 2009 | Bioorg. Med. Chem. | pmid:19147368 |
| Sagredo O et al. | Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease. | 2009 | Glia | pmid:19115380 |
| Miglio G et al. | PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss. | 2009 | Neurochem. Int. | pmid:19442697 |
| Duan S et al. | Lewis acid-catalyzed diastereoselective hydroarylation of benzylidene malonic esters. | 2009 | J. Org. Chem. | pmid:19518152 |
| Morrison HG et al. | Characterization of thermal behavior of deep eutectic solvents and their potential as drug solubilization vehicles. | 2009 | Int J Pharm | pmid:19477257 |
| Su KL et al. | Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme. | 2009 | Bioorg. Med. Chem. | pmid:19595601 |
| Cassidy AM et al. | Following the surface response of caffeine cocrystals to controlled humidity storage by atomic force microscopy. | 2009 | Int J Pharm | pmid:19539735 |
| Brunet N et al. | Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord. | 2009 | J. Comp. Neurol. | pmid:19634179 |
| Zhao L et al. | Synergetic effect of ultrasound with dual fields for the degradation of nitrobenzene in aqueous solution. | 2009 | Environ. Sci. Technol. | pmid:19673312 |
| Ohta Y et al. | Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization. | 2009 | J. Org. Chem. | pmid:19673483 |
| Elliott DW et al. | De-Pake-ing transform analysis of fully deuterated malonic acid. | 2009 | J. Magn. Reson. | pmid:19608443 |
| Mahoney MG et al. | Extracellular matrix in cutaneous ageing: the effects of 0.1% copper-zinc malonate-containing cream on elastin biosynthesis. | 2009 | Exp. Dermatol. | pmid:19400831 |
| Honda A et al. | Highly sensitive quantification of serum malonate, a possible marker for de novo lipogenesis, by LC-ESI-MS/MS. | 2009 | J. Lipid Res. | pmid:19403942 |
| Niwayama S and Cho H | Practical large scale synthesis of half-esters of malonic acid. | 2009 | Chem. Pharm. Bull. | pmid:19420784 |
| Liu Z et al. | Hypoglycemic effects of malonyl-ginsenosides extracted from roots of Panax ginseng on streptozotocin-induced diabetic mice. | 2009 | Phytother Res | pmid:19277974 |
| Lukyanova LD et al. | Energotropic effect of succinate-containing derivatives of 3-hydroxypyridine. | 2009 | Bull. Exp. Biol. Med. | pmid:20396747 |
| Iriti M and Faoro F | Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. | 2009 | Int J Mol Sci | pmid:20111684 |
| Yang L et al. | Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. | 2009 | PLoS ONE | pmid:19484125 |
| Brisse S et al. | Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization. | 2009 | PLoS ONE | pmid:19319196 |
| Blaquiere N et al. | Decarboxylative ketone aldol reactions: development and mechanistic evaluation under metal-free conditions. | 2009 | J. Org. Chem. | pmid:20560569 |
| Moore PK and Horsthemke W | Three-dimensional patterns in the Lengyel-Rabai-Epstein model of the chlorine dioxide-iodine-malonic acid reaction. | 2009 | Chaos | pmid:20059212 |
| Schmelz S et al. | AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. | 2009 | Nat. Chem. Biol. | pmid:19182782 |
| Yadav AV et al. | Co-crystals: a novel approach to modify physicochemical properties of active pharmaceutical ingredients. | 2009 | Indian J Pharm Sci | pmid:20502540 |
| Dalla-Betta P and Schulte M | Calculation of the aqueous thermodynamic properties of citric acid cycle intermediates and precursors and the estimation of high temperature and pressure equation of state parameters. | 2009 | Int J Mol Sci | pmid:19582231 |
| Ichida K | What lies behind serum urate concentration? Insights from genetic and genomic studies. | 2009 | Genome Med | pmid:20090896 |
| Tonouchi A | Isolation and characterization of a novel facultative anaerobic filamentous fungus from Japanese rice field soil. | 2009 | Int J Microbiol | pmid:20148171 |
| Foret J et al. | Synthesis and evaluation of non-hydrolyzable D-mannose 6-phosphate surrogates reveal 6-deoxy-6-dicarboxymethyl-D-mannose as a new strong inhibitor of phosphomannose isomerases. | 2009 | Bioorg. Med. Chem. | pmid:19783448 |
| Gebhard S et al. | The low-affinity phosphate transporter PitA is dispensable for in vitro growth of Mycobacterium smegmatis. | 2009 | BMC Microbiol. | pmid:20003273 |
| Spindler M et al. | Coenzyme Q10 effects in neurodegenerative disease. | 2009 | Neuropsychiatr Dis Treat | pmid:19966907 |
| Azuma Y and Ota M | An evaluation of minimal cellular functions to sustain a bacterial cell. | 2009 | BMC Syst Biol | pmid:19943949 |
| Tan Y et al. | Effects of precursor concentration and acidic sulfate in aqueous glyoxal-OH radical oxidation and implications for secondary organic aerosol. | 2009 | Environ. Sci. Technol. | pmid:19924930 |
| Spinks D et al. | Investigation of trypanothione reductase as a drug target in Trypanosoma brucei. | 2009 | ChemMedChem | pmid:19924760 |
| Pin C et al. | Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase. | 2009 | BMC Syst Biol | pmid:19917103 |
| Bar NS and Radde N | Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model. | 2009 | BMC Syst Biol | pmid:19903354 |
| Xu XM et al. | Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis. | 2009 | PLoS ONE | pmid:19865480 |
| Ramel C et al. | Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate. | 2009 | BMC Biochem. | pmid:19863801 |
| Perrot O et al. | Quantitative assessment of stereotyped and challenged locomotion after lesion of the striatum: a 3D kinematic study in rats. | 2009 | PLoS ONE | pmid:19859550 |
| Baldwin A et al. | Multilocus sequence typing of Cronobacter sakazakii and Cronobacter malonaticus reveals stable clonal structures with clinical significance which do not correlate with biotypes. | 2009 | BMC Microbiol. | pmid:19852808 |
| Kozjak-Pavlovic V et al. | Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis. | 2009 | PLoS Pathog. | pmid:19851451 |
| Strickler MA et al. | Functional characterization of a Na(+)-coupled dicarboxylate transporter from Bacillus licheniformis. | 2009 | Biochim. Biophys. Acta | pmid:19840771 |
| Goldstein P et al. | Clustering of protein domains for functional and evolutionary studies. | 2009 | BMC Bioinformatics | pmid:19832975 |
| Niimi M et al. | Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. | 2009 | J. Biomed. Sci. | pmid:19825180 |
| Rintala E et al. | Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. | 2009 | BMC Genomics | pmid:19804647 |
| Ndinguri MW et al. | Peptide targeting of platinum anti-cancer drugs. | 2009 | Bioconjug. Chem. | pmid:19775102 |
| Vyas P and Gulati A | Organic acid production in vitro and plant growth promotion in maize under controlled environment by phosphate-solubilizing fluorescent Pseudomonas. | 2009 | BMC Microbiol. | pmid:19698133 |
| Shoukry EM | Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents. | 2009 | Bioinorg Chem Appl | pmid:19696935 |
| Senoglu M et al. | Intraperitoneal Alpha-Lipoic Acid to prevent neural damage after crush injury to the rat sciatic nerve. | 2009 | J Brachial Plex Peripher Nerve Inj | pmid:19939272 |
| Juhnke HD et al. | Production, characterization and determination of the real catalytic properties of the putative 'succinate dehydrogenase' from Wolinella succinogenes. | 2009 | Mol. Microbiol. | pmid:19170876 |