Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Acne Keloid D000153 1 associated lipids
Alopecia Areata D000506 6 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Erythema D004890 22 associated lipids
Facial Dermatoses D005148 7 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Per page 10 20 50 100 | Total 511
Authors Title Published Journal PubMed Link
Ziel K et al. Cumulative irritation potential of metronidazole gel compared to azelaic acid gel after repeated applications to healthy skin. 2005 Nov-Dec J Drugs Dermatol pmid:16302558
Sasmaz S and Arican O Comparison of azelaic acid and anthralin for the therapy of patchy alopecia areata: a pilot study. 2005 Am J Clin Dermatol pmid:16343028
Nally JB and Berson DS Topical therapies for rosacea. 2006 J Drugs Dermatol pmid:16468288
Fleischer AB The evolution of azelaic acid. 2006 Cutis pmid:16566281
Draelos ZD The rationale for advancing the formulation of azelaic acid vehicles. 2006 Cutis pmid:16566282
Elewski B and Thiboutot D A clinical overview of azelaic acid. 2006 Cutis pmid:16566283
Bikowski JB Case studies. 2006 Cutis pmid:16566284
Del Rosso JQ The use of topical azelaic acid for common skin disorders other than inflammatory rosacea. 2006 Cutis pmid:16566285
pmid:16631968
Worret WI and Fluhr JW [Acne therapy with topical benzoyl peroxide, antibiotics and azelaic acid]. 2006 J Dtsch Dermatol Ges pmid:16638058
Wolf JE et al. Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. 2006 Cutis pmid:16706244
pmid:16737240
[Azelaic Acid--a new application in acne therapy. Expert's exchange. Berlin, 18-20 January 1991]. 1991 Hautarzt pmid:1674505
Hung HM et al. Products and mechanisms of the reaction of oleic acid with ozone and nitrate radical. 2005 J Phys Chem A pmid:16833788
Liu RH et al. Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. 2006 Arch Dermatol pmid:16924055
Goodman G Managing acne vulgaris effectively. 2006 Aust Fam Physician pmid:16969442
Purdy S Acne vulgaris. 2006 Clin Evid pmid:16973084
pmid:17014483
Weschler CJ Ozone's impact on public health: contributions from indoor exposures to ozone and products of ozone-initiated chemistry. 2006 Environ. Health Perspect. pmid:17035131
Zhang JF et al. [Studies on chemical constituents in root tuber of Cynanchum auriculatum]. 2006 Zhongguo Zhong Yao Za Zhi pmid:17048663