| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acne Vulgaris | D000152 | 35 associated lipids |
| Acne Keloid | D000153 | 1 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Drug Eruptions | D003875 | 30 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Erythema | D004890 | 22 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
Azelaic acid
Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
Cross Reference
Introduction
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azelaic acid?
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azelaic acid
PubChem Associated disorders and diseases
What pathways are associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azelaic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azelaic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azelaic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azelaic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azelaic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Azelaic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gupta AK et al. | The treatment of melasma: a review of clinical trials. | 2006 | J. Am. Acad. Dermatol. | pmid:17097400 |
| Fitton A and Goa KL | Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders. | 1991 | Drugs | pmid:1712709 |
| pmid:17147560 | ||||
| Draelos ZD et al. | An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients. | 2006 | J Cosmet Dermatol | pmid:17173568 |
| van Zuuren EJ et al. | Systematic review of rosacea treatments. | 2007 | J. Am. Acad. Dermatol. | pmid:17190628 |
| Erbil H et al. | Efficacy and safety of serial glycolic acid peels and a topical regimen in the treatment of recalcitrant melasma. | 2007 | J. Dermatol. | pmid:17204097 |
| pmid:17249752 | ||||
| Bojar RA et al. | The in-vitro antimicrobial effects of azelaic acid upon Propionibacterium acnes strain P37. | 1991 | J. Antimicrob. Chemother. | pmid:1726169 |
| pmid:17268656 | ||||
| Hinz DC | Efficiency improvement for sulfated ash determination by usage of a microwave muffle furnace. | 2007 | J Pharm Biomed Anal | pmid:17280812 |
| Stinco G et al. | Relationship between sebostatic activity, tolerability and efficacy of three topical drugs to treat mild to moderate acne. | 2007 | J Eur Acad Dermatol Venereol | pmid:17309452 |
| Elewski BE | Rosacea trial comparing twice-daily azelaic acid gel 15% with once-daily metronidazole gel 1%. | 2007 | Cutis | pmid:17330623 |
| Del Rosso JQ et al. | Azelaic acid gel 15%: clinical versatility in the treatment of rosacea. | 2006 | Cutis | pmid:17354468 |
| Nojima S et al. | Contact sex pheromone components of the cowpea weevil, Callosobruchus maculatus. | 2007 | J. Chem. Ecol. | pmid:17394050 |
| pmid:17394294 | ||||
| Iraji F et al. | Efficacy of topical azelaic acid gel in the treatment of mild-moderate acne vulgaris. | 2007 Mar-Apr | Indian J Dermatol Venereol Leprol | pmid:17456913 |
| Gupta AK and Gover MD | Azelaic acid (15% gel) in the treatment of acne rosacea. | 2007 | Int. J. Dermatol. | pmid:17472690 |
| Alevizos A et al. | Acne treatments: consider these options--and issues. | 2007 | J Fam Pract | pmid:17475157 |
| Devereux M et al. | Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine). | 2006 | Bioinorg Chem Appl | pmid:17497019 |
| Colón LE et al. | Cumulative irritation potential among metronidazole gel 1%, metronidazole gel 0.75%, and azelaic acid gel 15%. | 2007 | Cutis | pmid:17500380 |