| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Erythema | D004890 | 22 associated lipids |
| Dermatitis, Seborrheic | D012628 | 10 associated lipids |
| Drug Eruptions | D003875 | 30 associated lipids |
| Keratosis | D007642 | 9 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Hyperpigmentation | D017495 | 11 associated lipids |
| Melanosis | D008548 | 4 associated lipids |
| Disease Resistance | D060467 | 12 associated lipids |
Azelaic acid
Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
Cross Reference
Introduction
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azelaic acid?
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azelaic acid
PubChem Associated disorders and diseases
What pathways are associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azelaic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azelaic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azelaic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azelaic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azelaic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Azelaic acid
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| Lim GH et al. | Plasmodesmata Localizing Proteins Regulate Transport and Signaling during Systemic Acquired Immunity in Plants. | 2016 | Cell Host Microbe | pmid:27078071 |
| Helfrich YR and Maier LM | Topical and oral therapeutic approach to rosacea. | 2016 | Semin Cutan Med Surg | pmid:27416312 |
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| Aytekin M et al. | Formulation and characterization of liquid crystal systems containing azelaic acid for topical delivery. | 2013 | Drug Dev Ind Pharm | pmid:22480294 |
| Maes M et al. | Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic depression and neuroprogression. | 2013 | J Affect Disord | pmid:22898471 |
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| Muthulakshmi S and Saravanan R | Efficacy of azelaic acid on hepatic key enzymes of carbohydrate metabolism in high fat diet induced type 2 diabetic mice. | 2013 | Biochimie | pmid:23402910 |
| Quigley EA and Halpern AC | Microinvasive melanoma: cutaneous pharmacotherapeutic approaches. | 2013 | Am J Clin Dermatol | pmid:23479385 |
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| Yu K et al. | A feedback regulatory loop between G3P and lipid transfer proteins DIR1 and AZI1 mediates azelaic-acid-induced systemic immunity. | 2013 | Cell Rep | pmid:23602565 |
| Woolery-Lloyd HC et al. | Retinoids and azelaic acid to treat acne and hyperpigmentation in skin of color. | 2013 | J Drugs Dermatol | pmid:23652891 |
| Reis CP et al. | Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. | 2013 | Microsc. Microanal. | pmid:23673203 |
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