Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Aytekin M et al. | Formulation and characterization of liquid crystal systems containing azelaic acid for topical delivery. | 2013 | Drug Dev Ind Pharm | pmid:22480294 |
Maes M et al. | Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic depression and neuroprogression. | 2013 | J Affect Disord | pmid:22898471 |
Bayerl C | [Acne therapy in pregnancy]. | 2013 | Hautarzt | pmid:23430167 |
Muthulakshmi S and Saravanan R | Efficacy of azelaic acid on hepatic key enzymes of carbohydrate metabolism in high fat diet induced type 2 diabetic mice. | 2013 | Biochimie | pmid:23402910 |
Quigley EA and Halpern AC | Microinvasive melanoma: cutaneous pharmacotherapeutic approaches. | 2013 | Am J Clin Dermatol | pmid:23479385 |
Han S et al. | Application of HPLC with ELSD detection for the assessment of azelaic acid impurities in liposomal formulation. | 2013 | ScientificWorldJournal | pmid:24228008 |
von Schönfels W et al. | Metabolic signature of electrosurgical liver dissection. | 2013 | PLoS ONE | pmid:24058442 |
Coda AB et al. | Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel. | 2013 | J. Am. Acad. Dermatol. | pmid:23871720 |
Draelos ZD et al. | Azelaic acid foam 15% in the treatment of papulopustular rosacea: a randomized, double-blind, vehicle-controlled study. | 2013 | Cutis | pmid:24416747 |
Zheng P et al. | A novel urinary metabolite signature for diagnosing major depressive disorder. | 2013 | J. Proteome Res. | pmid:24224655 |