Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thiboutot D et al. | Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: results from two vehicle-controlled, randomized phase III studies. | 2003 | J. Am. Acad. Dermatol. | pmid:12789172 |
Webster G | Combination azelaic acid therapy for acne vulgaris. | 2000 | J. Am. Acad. Dermatol. | pmid:10898830 |
Sheth VM and Pandya AG | Melasma: a comprehensive update: part II. | 2011 | J. Am. Acad. Dermatol. | pmid:21920242 |
Elewski BE et al. | In reference to the October 2004 comprehensive overview of rosacea therapy. | 2007 | J. Am. Acad. Dermatol. | pmid:17870440 |
Kameyama K et al. | Treatment of reticulate acropigmentation of Kitamura with azelaic acid. An immunohistochemical and electron microscopic study. | 1992 | J. Am. Acad. Dermatol. | pmid:1613143 |
Gupta AK et al. | The treatment of melasma: a review of clinical trials. | 2006 | J. Am. Acad. Dermatol. | pmid:17097400 |
van Zuuren EJ et al. | Systematic review of rosacea treatments. | 2007 | J. Am. Acad. Dermatol. | pmid:17190628 |
Nazzaro-Porro M | Azelaic acid. | 1987 | J. Am. Acad. Dermatol. | pmid:2963038 |
Coda AB et al. | Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel. | 2013 | J. Am. Acad. Dermatol. | pmid:23871720 |
Wu YH et al. | Effects of Chinese herbal medicine combined with He-Ne laser on lipoperoxide and superoxide dismutase in chloasma patients. | 2009 | J Tradit Chin Med | pmid:19894376 |