Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Parodi A et al. | Treatment of rosacea. | 2011 | Ann Dermatol Venereol | pmid:22183101 |
Parodi A et al. | [Treatment of rosacea]. | 2011 | Ann Dermatol Venereol | pmid:21907876 |
Ortonne JP | [Depigmenting chemical agents]. | 1986 | Ann Dermatol Venereol | pmid:3800227 |
Januszewski AS et al. | Lipid-derived modifications of plasma proteins in experimental and human diabetes. | 2005 | Ann. N. Y. Acad. Sci. | pmid:16037262 |
Zaffaroni N et al. | Cytotoxic activity of azelaic acid against human melanoma primary cultures and established cell lines. | 1990 Nov-Dec | Anticancer Res. | pmid:2285231 |
Száraz I and Forsling W | Interaction between a capacitor electrolyte and gamma-aluminum oxide studied by Fourier transform infrared spectroscopy. | 2003 | Appl Spectrosc | pmid:14658693 |
Elewski BE et al. | A comparison of 15% azelaic acid gel and 0.75% metronidazole gel in the topical treatment of papulopustular rosacea: results of a randomized trial. | 2003 | Arch Dermatol | pmid:14623704 |
Czernielewski J and Liu Y | Comparison of 15% azelaic acid gel and 0.75% metronidazole gel for the topical treatment of papulopustular rosacea. | 2004 | Arch Dermatol | pmid:15492198 |
Liu RH et al. | Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. | 2006 | Arch Dermatol | pmid:16924055 |
Wilkerson MG and Wilkin JK | Azelaic acid esters do not depigment pigmented guinea pig skin. | 1990 | Arch Dermatol | pmid:2301969 |