Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Iraji F et al. | Efficacy of 15% azelaic acid in psoriasis vulgaris: a randomized, controlled clinical trial. | 2010 | J Drugs Dermatol | pmid:20684146 |
Kircik LH | Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study. | 2011 | J Drugs Dermatol | pmid:21637899 |
Wheeland RG and Dhawan S | Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. | 2011 | J Drugs Dermatol | pmid:21637900 |
Que SK and Bergstrom KG | Hyperpigmentation: old problem, new therapies. | 2009 | J Drugs Dermatol | pmid:19746682 |
Thiboutot DM et al. | A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. | 2009 | J Drugs Dermatol | pmid:19588640 |
Ziel K et al. | Cumulative irritation potential of metronidazole gel compared to azelaic acid gel after repeated applications to healthy skin. | 2005 Nov-Dec | J Drugs Dermatol | pmid:16302558 |
Fleischer A and Suephy C | The face and mind evaluation study: an examination of the efficacy of rosacea treatment using physician ratings and patients' self-reported quality of life. | 2005 Sep-Oct | J Drugs Dermatol | pmid:16167417 |
Thiboutot DM et al. | Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea. | 2008 | J Drugs Dermatol | pmid:18561584 |
Bhatia ND and Del Rosso JQ | Optimal management of papulopustular rosacea: rationale for combination therapy. | 2012 | J Drugs Dermatol | pmid:22777226 |
Woolery-Lloyd HC et al. | Retinoids and azelaic acid to treat acne and hyperpigmentation in skin of color. | 2013 | J Drugs Dermatol | pmid:23652891 |