Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Del Rosso JQ et al. | Efficacy of topical azelaic acid (AzA) gel 15% plus oral doxycycline 40 mg versus metronidazole gel 1% plus oral doxycycline 40 mg in mild-to-moderate papulopustular rosacea. | 2010 | J Drugs Dermatol | pmid:20645521 |
Conde JF et al. | Managing rosacea: a review of the use of metronidazole alone and in combination with oral antibiotics. | 2007 | J Drugs Dermatol | pmid:17679183 |
Thiboutot D | Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris. | 2008 | J Drugs Dermatol | pmid:18246693 |
Nally JB and Berson DS | Topical therapies for rosacea. | 2006 | J Drugs Dermatol | pmid:16468288 |
Del Rosso JQ and Kircik LH | Update on the management of rosacea: a status report on the current role and new horizons with topical azelaic acid. | 2014 | J Drugs Dermatol | pmid:25607798 |
Jackson JM et al. | Efficacy of extended-release 45 mg oral minocycline and extended-release 45 mg oral minocycline plus 15% azelaic acid in the treatment of acne rosacea. | 2013 | J Drugs Dermatol | pmid:23545911 |
Shalita AR et al. | Inflammatory acne management with a novel prescription dietary supplement. | 2012 | J Drugs Dermatol | pmid:23377512 |
Fluhr JW and Degitz K | [Antibiotics, azelaic acid and benzoyl peroxide in topical acne therapy]. | 2010 | J Dtsch Dermatol Ges | pmid:20482689 |
Gollnick HP et al. | [Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies]. | 2004 | J Dtsch Dermatol Ges | pmid:16281587 |
Worret WI and Fluhr JW | [Acne therapy with topical benzoyl peroxide, antibiotics and azelaic acid]. | 2006 | J Dtsch Dermatol Ges | pmid:16638058 |