Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shemer A et al. | Azelaic acid (20%) cream in the treatment of acne vulgaris. | 2002 | J Eur Acad Dermatol Venereol | pmid:12046832 |
Korting HC and Schöllmann C | Current topical and systemic approaches to treatment of rosacea. | 2009 | J Eur Acad Dermatol Venereol | pmid:19508315 |
Elewski BE et al. | Rosacea - global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert Group. | 2011 | J Eur Acad Dermatol Venereol | pmid:20586834 |
Stinco G et al. | Relationship between sebostatic activity, tolerability and efficacy of three topical drugs to treat mild to moderate acne. | 2007 | J Eur Acad Dermatol Venereol | pmid:17309452 |
Mostafa FF et al. | Comparative study of some treatment modalities of rosacea. | 2009 | J Eur Acad Dermatol Venereol | pmid:18705632 |
Kanitakis J | Linea fusca in a male adolescent successfully treated with azelaic acid. | 2008 | J Eur Acad Dermatol Venereol | pmid:18331308 |
Gollnick H and Schramm M | Topical therapy in acne. | 1998 | J Eur Acad Dermatol Venereol | pmid:9891903 |
Liao DC | Management of acne. | 2003 | J Fam Pract | pmid:12540312 |
Alevizos A et al. | Acne treatments: consider these options--and issues. | 2007 | J Fam Pract | pmid:17475157 |
Punsalan T and Usatine RP | Red facial rash with "granitos". | 2005 | J Fam Pract | pmid:16144591 |