Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Acne Keloid D000153 1 associated lipids
Alopecia Areata D000506 6 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Erythema D004890 22 associated lipids
Facial Dermatoses D005148 7 associated lipids
Heart Failure D006333 36 associated lipids
Inflammation D007249 119 associated lipids
Keratosis D007642 9 associated lipids
Leukemia D007938 74 associated lipids
Melanoma D008545 69 associated lipids
Melanosis D008548 4 associated lipids
Pain D010146 64 associated lipids
Pituitary Apoplexy D010899 1 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Psoriasis D011565 47 associated lipids
Rhinophyma D012224 1 associated lipids
Rosacea D012393 13 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperpigmentation D017495 11 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Disease Resistance D060467 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Sand M et al. Cutaneous lesions of the nose. 2010 Head Face Med pmid:20525327
Truman WM et al. Arabidopsis auxin mutants are compromised in systemic acquired resistance and exhibit aberrant accumulation of various indolic compounds. 2010 Plant Physiol. pmid:20081042
Chaouch S et al. Peroxisomal hydrogen peroxide is coupled to biotic defense responses by ISOCHORISMATE SYNTHASE1 in a daylength-related manner. 2010 Plant Physiol. pmid:20543092
Barabash R et al. [Nelson syndrome: a rare cause of generalized hyperpigmentation of the skin]. 2010 Jan-Feb Actas Dermosifiliogr pmid:20109395
Ghosh S Chemical leukoderma: what's new on etiopathological and clinical aspects? 2010 Jul-Sep Indian J Dermatol pmid:21063518
Jansen T et al. Steroid-induced periorificial dermatitis in children--clinical features and response to azelaic acid. 2010 Mar-Apr Pediatr Dermatol pmid:19804495
Karavelidis V et al. Evaluating the effects of crystallinity in new biocompatible polyester nanocarriers on drug release behavior. 2011 Int J Nanomedicine pmid:22162659
Staroverov SA et al. Biodynamic parameters of micellar diminazene in sheep erythrocytes and blood plasma. 2011 J. Vet. Sci. pmid:22122895
Vinaixa M et al. Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy. 2011 PLoS ONE pmid:22194988
Chudasama A et al. Investigation of microemulsion system for transdermal delivery of itraconazole. 2011 J Adv Pharm Technol Res pmid:22171289