Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Melnik BC et al. | Anti-acne agents attenuate FGFR2 signal transduction in acne. | 2009 | J. Invest. Dermatol. | pmid:19225542 |
Clark AA et al. | Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction. | 2016 | J. Leukoc. Biol. | pmid:27154353 |
Kawai Y et al. | Immunochemical detection of a novel lysine adduct using an antibody to linoleic acid hydroperoxide-modified protein. | 2003 | J. Lipid Res. | pmid:12700336 |
Passi S et al. | Metabolism of straight saturated medium chain length (C9 to C12) dicarboxylic acids. | 1983 | J. Lipid Res. | pmid:6631243 |
Januszewski AS et al. | Chemical modification of proteins during peroxidation of phospholipids. | 2005 | J. Lipid Res. | pmid:15805546 |
Seidler J et al. | Identification and prediction of promiscuous aggregating inhibitors among known drugs. | 2003 | J. Med. Chem. | pmid:14521410 |
Daverat P et al. | Identification and characterization of anti-conjugated azelaic acid antibodies in multiple sclerosis. | 1989 | J. Neuroimmunol. | pmid:2925840 |
Cluzeau J and Lubell WD | Conformationally constrained dipeptide surrogates with aromatic side-chains: synthesis of 4-aryl indolizidin-9-one amino acids by conjugate addition to a common alpha,omega-diaminoazelate enone intermediate. | 2004 | J. Org. Chem. | pmid:14987004 |
Gwak HS et al. | Analgesic effects of intra-nasal enkephalins. | 2003 | J. Pharm. Pharmacol. | pmid:14604463 |
Zheng P et al. | A novel urinary metabolite signature for diagnosing major depressive disorder. | 2013 | J. Proteome Res. | pmid:24224655 |