Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nazzaro-Porro M | Azelaic acid. | 1987 | J. Am. Acad. Dermatol. | pmid:2963038 |
Piquero MartÃn J et al. | [Double-blind clinical study of the treatment of melasma with azelaic acid versus hydroquinone]. | 1988 | Med Cutan Ibero Lat Am | pmid:3073279 |
Mingrone G et al. | Influence of sodium salts of saturated medium chain length (C6, C9, C10 and C12) dicarboxylic acids on the uterine horn of rat in vitro. | 1988 | Q J Exp Physiol | pmid:3164112 |
Stamatiadis D et al. | Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid. | 1988 | Br. J. Dermatol. | pmid:3207614 |
Sowden J et al. | Malignant melanoma arising in the scar of lupus vulgaris and response to treatment with topical azelaic acid. | 1988 | Clin. Exp. Dermatol. | pmid:3256454 |
Azelaic acid in lentigo maligna. | 1987 | Br. J. Dermatol. | pmid:3580294 | |
Schallreuter KU and Wood JM | Azelaic acid as a competitive inhibitor of thioredoxin reductase in human melanoma cells. | 1987 | Cancer Lett. | pmid:3652030 |
Grosshans E and Chartier C | [Therapeutic depigmentation agents]. | 1987 | Schweiz. Rundsch. Med. Prax. | pmid:3671942 |
Geier G et al. | [Effect of azelaic acid on the growth of melanoma cell cultures in comparison with fibroblast cultures]. | 1986 | Hautarzt | pmid:3700102 |
McLean DI and Peter KK | Apparent progression of lentigo maligna to invasive melanoma during treatment with topical azelaic acid. | 1986 | Br. J. Dermatol. | pmid:3718862 |