Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Reis CP et al. | Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. | 2013 | Microsc. Microanal. | pmid:23673203 |
Schnopp C and Mempel M | Acne vulgaris in children and adolescents. | 2011 | Minerva Pediatr. | pmid:21909065 |
Koczorek M | ["Cleansing, topical treatment, oral administration". Controlling acne]. | 2001 | MMW Fortschr Med | pmid:11524979 |
Muthulakshmi S and Saravanan R | Protective effects of azelaic acid against high-fat diet-induced oxidative stress in liver, kidney and heart of C57BL/6J mice. | 2013 | Mol. Cell. Biochem. | pmid:23361364 |
Grammatico P et al. | Karyotype modifications in human malignant melanoma cell cultures after treatment with azelaic acid. | 1993 | Mutat. Res. | pmid:7685492 |
Garelnabi M et al. | Evaluation of a gas chromatography method for azelaic acid determination in selected biological samples. | 2010 | N Am J Med Sci | pmid:22558586 |
Chagnaud JL et al. | Monoclonal anti-conjugated azelaic acid antibody production: application to multiple sclerosis. | 1990 | Neuroreport | pmid:2129868 |
Roebuck HL | Face up to rosacea. | 2005 | Nurse Pract | pmid:16151303 |
U-Taniguchi Y et al. | Cell cycle inhibition of HTLV-I transformed T cell lines by retinoic acid: the possible therapeutic use of thioredoxin reductase inhibitors. | 1995 | Oncol. Res. | pmid:8555652 |
Gung BW and Dickson H | Total synthesis of (-)-minquartynoic acid: an anti-cancer, anti-HIV natural product. | 2002 | Org. Lett. | pmid:12123365 |