Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Reis CP et al. | Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. | 2013 | Microsc. Microanal. | pmid:23673203 |
Briganti S et al. | Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ. | 2013 | Exp. Dermatol. | pmid:23278893 |
Pazoki-Toroudi H et al. | Therapeutic effects of minoxidil high extra combination therapy in patients with androgenetic alopecia. | 2012 Sep-Oct | Skinmed | pmid:23163069 |
Sarkar R et al. | Newer and upcoming therapies for melasma. | 2012 Jul-Aug | Indian J Dermatol Venereol Leprol | pmid:22772611 |
Simonart T | Newer approaches to the treatment of acne vulgaris. | 2012 | Am J Clin Dermatol | pmid:22920095 |
Li N et al. | Effect of ionization and vehicle on skin absorption and penetration of azelaic acid. | 2012 | Drug Dev Ind Pharm | pmid:22111946 |
Zoeller M et al. | Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid. | 2012 | Plant Physiol. | pmid:22822212 |
Bhatia ND and Del Rosso JQ | Optimal management of papulopustular rosacea: rationale for combination therapy. | 2012 | J Drugs Dermatol | pmid:22777226 |
Shalita AR et al. | Inflammatory acne management with a novel prescription dietary supplement. | 2012 | J Drugs Dermatol | pmid:23377512 |
Matsubara T et al. | Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis. | 2012 | Cell Metab. | pmid:23140643 |