Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:20017486 | ||||
Sobottka A and Lehmann P | [Rosacea 2009 : new advances in pathophysiology, clinical staging and therapeutic strategies]. | 2009 | Hautarzt | pmid:19957073 |
Fujitani K et al. | Preparation of polycarboxylic acids by oxidative cleavage with oxygen / Co-Mn-Br system. | 2009 | J Oleo Sci | pmid:19915320 |
pmid:19907406 | ||||
Wu YH et al. | Effects of Chinese herbal medicine combined with He-Ne laser on lipoperoxide and superoxide dismutase in chloasma patients. | 2009 | J Tradit Chin Med | pmid:19894376 |
Litvinov D et al. | Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. | 2010 | Atherosclerosis | pmid:19880116 |
Ebanks JP et al. | Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration. | 2009 | Int J Mol Sci | pmid:19865532 |
Elsaie ML and Choudhary S | Updates on the pathophysiology and management of acne rosacea. | 2009 | Postgrad Med | pmid:19820288 |
Jansen T et al. | Steroid-induced periorificial dermatitis in children--clinical features and response to azelaic acid. | 2010 Mar-Apr | Pediatr Dermatol | pmid:19804495 |
Panyosak A et al. | Safety assessment of azelaic acid and its derivatives entrapped in nanovesicles. | 2009 | Hum Exp Toxicol | pmid:19755450 |
Del Rosso JQ | The use of moisturizers as an integral component of topical therapy for rosacea: clinical results based on the Assessment of Skin Characteristics Study. | 2009 | Cutis | pmid:19746764 |
Que SK and Bergstrom KG | Hyperpigmentation: old problem, new therapies. | 2009 | J Drugs Dermatol | pmid:19746682 |
Goldgar C et al. | Treatment options for acne rosacea. | 2009 | Am Fam Physician | pmid:19725487 |
pmid:19643540 | ||||
Lanz C et al. | Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm. | 2009 | Radiat. Res. | pmid:19630524 |
Shah J | Plants under attack: systemic signals in defence. | 2009 | Curr. Opin. Plant Biol. | pmid:19608451 |
pmid:19608057 | ||||
Thiboutot DM et al. | A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. | 2009 | J Drugs Dermatol | pmid:19588640 |
Culp B and Scheinfeld N | Rosacea: a review. | 2009 | P T | pmid:19562004 |
Korting HC and Schöllmann C | Current topical and systemic approaches to treatment of rosacea. | 2009 | J Eur Acad Dermatol Venereol | pmid:19508315 |
Bowler PJ | Impact on facial rejuvenation with dermatological preparations. | 2009 | Clin Interv Aging | pmid:19503770 |
pmid:19465852 | ||||
Purdy S and Deberker D | Acne vulgaris. | 2008 | BMJ Clin Evid | pmid:19450306 |
Parker JE | The quest for long-distance signals in plant systemic immunity. | 2009 | Sci Signal | pmid:19436056 |
pmid:19433342 | ||||
Del Rosso JQ et al. | Impact of order of application of moisturizers on percutaneous absorption kinetics: evaluation of sequential application of moisturizer lotions and azelaic acid gel 15% using a human skin model. | 2009 | Cutis | pmid:19363903 |
Jung HW et al. | Priming in systemic plant immunity. | 2009 | Science | pmid:19342588 |
Gooderham M | Rosacea and its topical management. | 2009 | Skin Therapy Lett. | pmid:19330270 |
Melnik BC et al. | Anti-acne agents attenuate FGFR2 signal transduction in acne. | 2009 | J. Invest. Dermatol. | pmid:19225542 |
pmid:19160531 | ||||
pmid:19126734 | ||||
Bertuzzi A et al. | Pharmacokinetic analysis of azelaic acid disodium salt. A proposed substrate for total parenteral nutrition. | 1991 | Clin Pharmacokinet | pmid:1908756 |
pmid:19055345 | ||||
pmid:19022456 | ||||
Lee GS | Intravenous vitamin C in the treatment of post-laser hyperpigmentation for melasma: a short report. | 2008 | J Cosmet Laser Ther | pmid:18830869 |
Gollnick H and Layton A | Azelaic acid 15% gel in the treatment of rosacea. | 2008 | Expert Opin Pharmacother | pmid:18803456 |
Rup S et al. | The ultrasound-assisted oxidative scission of monoenic fatty acids by ruthenium tetroxide catalysis: influence of the mixture of solvents. | 2009 | Ultrason Sonochem | pmid:18799341 |
pmid:18728922 | ||||
Mostafa FF et al. | Comparative study of some treatment modalities of rosacea. | 2009 | J Eur Acad Dermatol Venereol | pmid:18705632 |
Akamatsu H et al. | Inhibitory effect of azelaic acid on neutrophil functions: a possible cause for its efficacy in treating pathogenetically unrelated diseases. | 1991 | Arch. Dermatol. Res. | pmid:1867478 |
pmid:18641447 | ||||
Crea F et al. | Sequestering ability of polycarboxylic ligands towards dioxouranium(VI). | 2008 | Talanta | pmid:18585146 |
Thiboutot DM et al. | Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea. | 2008 | J Drugs Dermatol | pmid:18561584 |
pmid:18535811 | ||||
Piskin S and Uzunali E | A review of the use of adapalene for the treatment of acne vulgaris. | 2007 | Ther Clin Risk Manag | pmid:18472984 |
Stewart JJ | Application of the PM6 method to modeling the solid state. | 2008 | J Mol Model | pmid:18449579 |
De Filippis D et al. | Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats. | 2009 | J. Cell. Mol. Med. | pmid:18429935 |
pmid:18394082 | ||||
Gollnick H | [Azelaic acid for keratinization disorders?]. | 1991 | Med Monatsschr Pharm | pmid:1838401 |
pmid:18377339 |