Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Robins EJ et al. | Effect of dicarboxylic acids on Harding-Passey and Cloudman S91 melanoma cells in tissue culture. | 1985 | J. Invest. Dermatol. | pmid:4031537 |
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Robins EJ et al. | Effectiveness of azelaic acid as a depigmenting and chemotherapeutic agent. | 1986 | J. Invest. Dermatol. | pmid:3734479 |
Ward BJ et al. | Effect of L-carnitine on cultured murine melanoma cells exposed to azelaic acid. | 1986 | J. Invest. Dermatol. | pmid:3745962 |
Pathak MA et al. | An evaluation of the effectiveness of azelaic acid as a depigmenting and chemotherapeutic agent. | 1985 | J. Invest. Dermatol. | pmid:4031538 |
Leibl H et al. | Inhibition of DNA synthesis of melanoma cells by azelaic acid. | 1985 | J. Invest. Dermatol. | pmid:4056455 |
Nazzaro-Porro M et al. | Effect of dicarboxylic acids on lentigo maligna. | 1979 | J. Invest. Dermatol. | pmid:448162 |
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Daverat P et al. | Identification and characterization of anti-conjugated azelaic acid antibodies in multiple sclerosis. | 1989 | J. Neuroimmunol. | pmid:2925840 |
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Tacchino RM et al. | Short-term infusion of azelaic acid vs intralipid in healthy subjects evaluated by indirect calorimetry. | 1990 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:2112625 |
Mingrone G et al. | Preliminary studies of a dicarboxylic acid as an energy substrate in man. | 1989 May-Jun | JPEN J Parenter Enteral Nutr | pmid:2503641 |
Nazzaro-Porro M et al. | Effect of azelaic acid on human malignant melanoma. | 1980 | Lancet | pmid:6103442 |
Azelaic acid, a new treatment for rosacea. | 2004 | Mayo Clin Womens Healthsource | pmid:15152174 | |
Piquero MartÃn J et al. | [Double-blind clinical study of the treatment of melasma with azelaic acid versus hydroquinone]. | 1988 | Med Cutan Ibero Lat Am | pmid:3073279 |
Azelaic acid (Finacea) for rosacea. | 2003 | Med Lett Drugs Ther | pmid:12968125 | |
Azelaic acid-a new topical drug for acne. | 1996 | Med Lett Drugs Ther | pmid:8637482 | |
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