Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Acne Vulgaris D000152 35 associated lipids
Acne Keloid D000153 1 associated lipids
Alopecia Areata D000506 6 associated lipids
Arteriosclerosis D001161 86 associated lipids
Body Weight D001835 333 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Erythema D004890 22 associated lipids
Facial Dermatoses D005148 7 associated lipids
Heart Failure D006333 36 associated lipids
Inflammation D007249 119 associated lipids
Keratosis D007642 9 associated lipids
Leukemia D007938 74 associated lipids
Melanoma D008545 69 associated lipids
Melanosis D008548 4 associated lipids
Pain D010146 64 associated lipids
Pituitary Apoplexy D010899 1 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Psoriasis D011565 47 associated lipids
Rhinophyma D012224 1 associated lipids
Rosacea D012393 13 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperpigmentation D017495 11 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Disease Resistance D060467 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

Download all related citations
Per page 10 20 50 100 | Total 511
Authors Title Published Journal PubMed Link
Merkviladze N et al. The efficacy of topical drugs in treatment of noninflammatory acne vulgaris. 2010 Georgian Med News pmid:20972276
Pazoki-Toroudi H et al. Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. 2010 J Dermatolog Treat pmid:20394495
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Champigny MJ et al. Localization of DIR1 at the tissue, cellular and subcellular levels during Systemic Acquired Resistance in Arabidopsis using DIR1:GUS and DIR1:EGFP reporters. 2011 BMC Plant Biol. pmid:21896186
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McFalda WL and Roebuck HL Rational management of papulopustular rosacea with concomitant facial seborrheic dermatitis: a case report. 2011 J Clin Aesthet Dermatol pmid:21278898
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Cuevas P et al. Long-term effectiveness of dobesilate in the treatment of papulopustular rosacea. 2011 BMJ Case Rep pmid:22675033
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Schnopp C and Mempel M Acne vulgaris in children and adolescents. 2011 Minerva Pediatr. pmid:21909065
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Sheth VM and Pandya AG Melasma: a comprehensive update: part II. 2011 J. Am. Acad. Dermatol. pmid:21920242
Yu L et al. Metabolomic phenotype of gastric cancer and precancerous stages based on gas chromatography time-of-flight mass spectrometry. 2011 J. Gastroenterol. Hepatol. pmid:21443661
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Farshi S Comparative study of therapeutic effects of 20% azelaic acid and hydroquinone 4% cream in the treatment of melasma. 2011 J Cosmet Dermatol pmid:22151936
Wang H et al. [Chemical constituents of Halenia elliptica]. 2011 Zhongguo Zhong Yao Za Zhi pmid:22779176
Vinaixa M et al. Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy. 2011 PLoS ONE pmid:22194988
Whitney KM and Ditre CM Management strategies for acne vulgaris. 2011 Clin Cosmet Investig Dermatol pmid:21691566
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Chudasama A et al. Investigation of microemulsion system for transdermal delivery of itraconazole. 2011 J Adv Pharm Technol Res pmid:22171289
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Salimon J et al. Synthesis and physical properties of estolide ester using saturated Fatty Acid and ricinoleic Acid. 2011 J Autom Methods Manag Chem pmid:22007150