Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid: | ||||
Breathnach AS | Azelaic acid: potential as a general antitumoural agent. | 1999 | Med. Hypotheses | pmid:10362281 |
Maddin S | A comparison of topical azelaic acid 20% cream and topical metronidazole 0.75% cream in the treatment of patients with papulopustular rosacea. | 1999 | J. Am. Acad. Dermatol. | pmid:10365928 |
Rocamora V et al. | Amelanotic lentigo maligna melanoma: report of a case and review of the literature. | 1999 | Cutis | pmid:10431675 |
Capristo E et al. | A new HPLC method for the direct analysis of triglycerides of dicarboxylic acids in biological samples. | 1999 | Clin. Chim. Acta | pmid:10556649 |
Bjerke R et al. | Double-blind comparison of azelaic acid 20% cream and its vehicle in treatment of papulo-pustular rosacea. | 1999 | Acta Derm. Venereol. | pmid:10598760 |
Russell JJ | Topical therapy for acne. | 2000 | Am Fam Physician | pmid:10670502 |
Thiboutot D | New treatments and therapeutic strategies for acne. | 2000 | Arch Fam Med | pmid:10693736 |
Usatine RP | The science and art of treating acne in adolescence. | 2000 | West. J. Med. | pmid:10734805 |
Korman SH et al. | Characteristic urine organic acid profile in peroxisomal biogenesis disorders. | 2000 | J. Inherit. Metab. Dis. | pmid:10896310 |
Webster G | Combination azelaic acid therapy for acne vulgaris. | 2000 | J. Am. Acad. Dermatol. | pmid:10898830 |
Hermanns JF et al. | Unraveling the patterns of subclinical pheomelanin-enriched facial hyperpigmentation: effect of depigmenting agents. | 2000 | Dermatology (Basel) | pmid:11053913 |
Gutheil WG | Application of hierarchical thermodynamic interactions to the protonation equilibria of organic polyprotic acids. | 2000 | Biophys. Chem. | pmid:11152269 |
Malaisse WJ et al. | Effects of aliphatic dioic acids and glycerol-1,2,3-tris(dodecanedioate) on D-glucose-stimulated insulin release in rat pancreatic islets. | 2000 | Br. J. Nutr. | pmid:11177188 |
pmid:11333444 | ||||
pmid:11451041 | ||||
Koczorek M | ["Cleansing, topical treatment, oral administration". Controlling acne]. | 2001 | MMW Fortschr Med | pmid:11524979 |
Gollnick HP et al. | Comparison of combined azelaic acid cream plus oral minocycline with oral isotretinoin in severe acne. | 2001 Nov-Dec | Eur J Dermatol | pmid:11701404 |
Pérez-Bernal A et al. | Management of facial hyperpigmentation. | 2000 Sep-Oct | Am J Clin Dermatol | pmid:11702317 |
Vereecken P and Heenen M | Recurrent lentigo maligna melanoma: regression associated with local azelaic acid 20%. | 2002 Jan-Feb | Int. J. Clin. Pract. | pmid:11831841 |
Shemer A et al. | Azelaic acid (20%) cream in the treatment of acne vulgaris. | 2002 | J Eur Acad Dermatol Venereol | pmid:12046832 |
Hermanns JF et al. | Assessment of topical hypopigmenting agents on solar lentigines of Asian women. | 2002 | Dermatology (Basel) | pmid:12077522 |
Gung BW and Dickson H | Total synthesis of (-)-minquartynoic acid: an anti-cancer, anti-HIV natural product. | 2002 | Org. Lett. | pmid:12123365 |
Rebora A | The management of rosacea. | 2002 | Am J Clin Dermatol | pmid:12180896 |
pmid:12221597 | ||||
Ruan H et al. | Structure of a novel diterpenoid ester, fritillahupehin from bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. | 2002 | Fitoterapia | pmid:12234570 |
Hojo Y et al. | Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism. | 2002 | Circ. Res. | pmid:12386148 |
Sarkar R et al. | A comparative study of 20% azelaic acid cream monotherapy versus a sequential therapy in the treatment of melasma in dark-skinned patients. | 2002 | Dermatology (Basel) | pmid:12399672 |
Ray SS et al. | Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor. | 2002 | Structure | pmid:12429091 |
Del Rosso JQ | A status report on the medical management of rosacea: focus on topical therapies. | 2002 | Cutis | pmid:12469780 |
pmid:12482495 | ||||
pmid:12489863 | ||||
Liao DC | Management of acne. | 2003 | J Fam Pract | pmid:12540312 |
pmid:12554974 | ||||
Brune TG et al. | Unknown peaks in GC-MS analyses of Guthrie cards blood samples might be the result of sample contamination by the black markings of the card. | 2002 | J. Inherit. Metab. Dis. | pmid:12555947 |
Gollnick HP and Krautheim A | Topical treatment in acne: current status and future aspects. | 2003 | Dermatology (Basel) | pmid:12566803 |
Herrero-MartÃnez JM et al. | Separation of homologues and isomers of linear alkylbenzenesulfonates by capillary electrophoresis with sodium dodecyl sulfate, carboxylic acids and bile salts. | 2003 | Electrophoresis | pmid:12601738 |
Kawai Y et al. | Immunochemical detection of a novel lysine adduct using an antibody to linoleic acid hydroperoxide-modified protein. | 2003 | J. Lipid Res. | pmid:12700336 |
Goulden V | Guidelines for the management of acne vulgaris in adolescents. | 2003 | Paediatr Drugs | pmid:12716217 |
He Y et al. | [Studies on chemical constituents of root of Cichorium intybus]. | 2002 | Zhongguo Zhong Yao Za Zhi | pmid:12774404 |
Thiboutot D et al. | Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: results from two vehicle-controlled, randomized phase III studies. | 2003 | J. Am. Acad. Dermatol. | pmid:12789172 |
Dong R and Yu LE | Investigation of surface changes of nanoparticles using TM-AFM phase imaging. | 2003 | Environ. Sci. Technol. | pmid:12854724 |
Azelaic acid (Finacea) for rosacea. | 2003 | Med Lett Drugs Ther | pmid:12968125 | |
Täuber U et al. | Percutaneous absorption of azelaic acid in humans. | 1992 | Exp. Dermatol. | pmid:1365318 |
JANOTA-BASSALIK L and WRIGHT LD | AZELAIC ACID UTILIZATION BY A PSEUDOMONAS. | 1964 | J. Gen. Microbiol. | pmid:14217352 |
Seidler J et al. | Identification and prediction of promiscuous aggregating inhibitors among known drugs. | 2003 | J. Med. Chem. | pmid:14521410 |
Gwak HS et al. | Analgesic effects of intra-nasal enkephalins. | 2003 | J. Pharm. Pharmacol. | pmid:14604463 |
pmid:14606932 | ||||
Elewski BE et al. | A comparison of 15% azelaic acid gel and 0.75% metronidazole gel in the topical treatment of papulopustular rosacea: results of a randomized trial. | 2003 | Arch Dermatol | pmid:14623704 |
Vermis K et al. | Burkholderia cepacia complex genomovars: utilization of carbon sources, susceptibility to antimicrobial agents and growth on selective media. | 2003 | J. Appl. Microbiol. | pmid:14632991 |