Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gordy JW et al. | Comparative Effectiveness of Potential Elicitors of Plant Resistance against Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae) in Four Crop Plants. | 2015 | PLoS ONE | pmid:26332833 |
Ganzetti G et al. | Rosacea: could topical azelaic acid and oral tetracyclines modify videocapillaroscopic pattern? | 2014 Mar-Apr | Skinmed | pmid:24933858 |
Gołębiowski M et al. | Antimicrobial activity of untypical lipid compounds in the cuticular and internal lipids of four fly species. | 2014 | J. Appl. Microbiol. | pmid:24238211 |
Wittek F et al. | Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 promotes systemic acquired resistance via azelaic acid and its precursor 9-oxo nonanoic acid. | 2014 | J. Exp. Bot. | pmid:25114016 |
Wang C et al. | Free radicals mediate systemic acquired resistance. | 2014 | Cell Rep | pmid:24726369 |
Shariff A et al. | Acne vulgaris in the context of complex medical co-morbities: the management of severe acne vulgaris in a female with retinitis pigmentosa - utilizing pulse dye laser in conjunction with medical therapy. | 2014 | Dermatol. Online J. | pmid:24656277 |
Del Rosso JQ and Kircik LH | Update on the management of rosacea: a status report on the current role and new horizons with topical azelaic acid. | 2014 | J Drugs Dermatol | pmid:25607798 |
Del Rosso JQ et al. | Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 5: a guide on the management of rosacea. | 2014 | Cutis | pmid:24738094 |
Han S et al. | Identification of unknown impurity of azelaic acid in liposomal formulation assessed by HPLC-ELSD, GC-FID, and GC-MS. | 2014 | AAPS PharmSciTech | pmid:24166667 |
Sieber MA and Hegel JK | Azelaic acid: Properties and mode of action. | 2014 | Skin Pharmacol Physiol | pmid:24280644 |