Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Disease Resistance D060467 12 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Hyperpigmentation D017495 11 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Rosacea D012393 13 associated lipids
Rhinophyma D012224 1 associated lipids
Psoriasis D011565 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Pituitary Apoplexy D010899 1 associated lipids
Pain D010146 64 associated lipids
Melanosis D008548 4 associated lipids
Melanoma D008545 69 associated lipids
Leukemia D007938 74 associated lipids
Keratosis D007642 9 associated lipids
Inflammation D007249 119 associated lipids
Heart Failure D006333 36 associated lipids
Facial Dermatoses D005148 7 associated lipids
Erythema D004890 22 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Drug Eruptions D003875 30 associated lipids
Body Weight D001835 333 associated lipids
Arteriosclerosis D001161 86 associated lipids
Alopecia Areata D000506 6 associated lipids
Acne Keloid D000153 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

Download all related citations
Per page 10 20 50 100 | Total 511
Authors Title Published Journal PubMed Link
Shirokova E et al. Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants. 2005 J. Biol. Chem. pmid:15598656
Yu JS and Kim AK Effect of combination of taurine and azelaic acid on antimelanogenesis in murine melanoma cells. 2010 J. Biomed. Sci. pmid:20804622
De Filippis D et al. Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats. 2009 J. Cell. Mol. Med. pmid:18429935
Nojima S et al. Contact sex pheromone components of the cowpea weevil, Callosobruchus maculatus. 2007 J. Chem. Ecol. pmid:17394050
Yoon TY et al. A case of idiopathic eruptive macular pigmentation. 2004 J. Dermatol. pmid:15187318
Erbil H et al. Efficacy and safety of serial glycolic acid peels and a topical regimen in the treatment of recalcitrant melasma. 2007 J. Dermatol. pmid:17204097
Oh CW and Myung KB An ultrastructural study of the retention hyperkeratosis of experimentally induced comedones in rabbits: the effects of three comedolytics. 1996 J. Dermatol. pmid:8935627
Wittek F et al. Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 promotes systemic acquired resistance via azelaic acid and its precursor 9-oxo nonanoic acid. 2014 J. Exp. Bot. pmid:25114016
Chae K et al. A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction. 2010 J. Exp. Bot. pmid:20667964
Yu L et al. Metabolomic phenotype of gastric cancer and precancerous stages based on gas chromatography time-of-flight mass spectrometry. 2011 J. Gastroenterol. Hepatol. pmid:21443661