Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Khanna N and Rasool S | Facial melanoses: Indian perspective. | 2011 Sep-Oct | Indian J Dermatol Venereol Leprol | pmid:21860153 |
Rozema E et al. | Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. | 2012 | Evid Based Complement Alternat Med | pmid:22675394 |
Zhao H et al. | Metabolomics-based study of clinical and animal plasma samples in coronary heart disease with blood stasis syndrome. | 2012 | Evid Based Complement Alternat Med | pmid:22675387 |
Lorenc-Kukula K et al. | Biochemical and Molecular-Genetic Characterization of SFD1's Involvement in Lipid Metabolism and Defense Signaling. | 2012 | Front Plant Sci | pmid:22645576 |
Reinholz M et al. | Cathelicidin LL-37: an antimicrobial peptide with a role in inflammatory skin disease. | 2012 | Ann Dermatol | pmid:22577261 |
Estronca LM et al. | Molecular etiology of atherogenesis--in vitro induction of lipidosis in macrophages with a new LDL model. | 2012 | PLoS ONE | pmid:22514671 |
Li N et al. | Effect of ionization and vehicle on skin absorption and penetration of azelaic acid. | 2012 | Drug Dev Ind Pharm | pmid:22111946 |
Zoeller M et al. | Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid. | 2012 | Plant Physiol. | pmid:22822212 |
Bhatia ND and Del Rosso JQ | Optimal management of papulopustular rosacea: rationale for combination therapy. | 2012 | J Drugs Dermatol | pmid:22777226 |
Hsieh PW et al. | The co-drug of conjugated hydroquinone and azelaic acid to enhance topical skin targeting and decrease penetration through the skin. | 2012 | Eur J Pharm Biopharm | pmid:22469554 |