Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Body Weight D001835 333 associated lipids
Heart Failure D006333 36 associated lipids
Facial Dermatoses D005148 7 associated lipids
Acne Vulgaris D000152 35 associated lipids
Melanoma D008545 69 associated lipids
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Psoriasis D011565 47 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Erythema D004890 22 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Drug Eruptions D003875 30 associated lipids
Keratosis D007642 9 associated lipids
Rosacea D012393 13 associated lipids
Hyperpigmentation D017495 11 associated lipids
Melanosis D008548 4 associated lipids
Disease Resistance D060467 12 associated lipids
Alopecia Areata D000506 6 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Rhinophyma D012224 1 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Pituitary Apoplexy D010899 1 associated lipids
Acne Keloid D000153 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

Download all related citations
Per page 10 20 50 100 | Total 511
Authors Title Published Journal PubMed Link
Wittek F et al. Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY1 promotes systemic acquired resistance via azelaic acid and its precursor 9-oxo nonanoic acid. 2014 J. Exp. Bot. pmid:25114016
Reis CP et al. Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment. 2014 Drug Dev Ind Pharm pmid:23480566
Woolery-Lloyd HC et al. Retinoids and azelaic acid to treat acne and hyperpigmentation in skin of color. 2013 J Drugs Dermatol pmid:23652891
Reis CP et al. Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. 2013 Microsc. Microanal. pmid:23673203
Briganti S et al. Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ. 2013 Exp. Dermatol. pmid:23278893
Muthulakshmi S and Saravanan R Protective effects of azelaic acid against high-fat diet-induced oxidative stress in liver, kidney and heart of C57BL/6J mice. 2013 Mol. Cell. Biochem. pmid:23361364
Chauhan N and Ellis DA Rosacea: pathophysiology and management principles. 2013 Facial Plast Surg Clin North Am pmid:23369595
Jackson JM et al. Efficacy of extended-release 45 mg oral minocycline and extended-release 45 mg oral minocycline plus 15% azelaic acid in the treatment of acne rosacea. 2013 J Drugs Dermatol pmid:23545911
Schöfer H [Topical therapy of rosacea]. 2013 Hautarzt pmid:23780475
Alzweiri M et al. Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker. 2013 J Sep Sci pmid:23893928