Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperpigmentation D017495 11 associated lipids
Disease Resistance D060467 12 associated lipids
Rosacea D012393 13 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Erythema D004890 22 associated lipids
Drug Eruptions D003875 30 associated lipids
Acne Vulgaris D000152 35 associated lipids
Heart Failure D006333 36 associated lipids
Psoriasis D011565 47 associated lipids
Per page 10 20 50 | Total 27

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Merkviladze N et al. The efficacy of topical drugs in treatment of noninflammatory acne vulgaris. 2010 Georgian Med News pmid:20972276
Preisz K and Kárpáti S [Rosacea: pathogenesis, clinical forms and therapy]. 2010 Orv Hetil pmid:20650811
Mastrofrancesco A et al. Azelaic acid modulates the inflammatory response in normal human keratinocytes through PPARgamma activation. 2010 Exp. Dermatol. pmid:20545756
Scheinfeld N and Berk T A review of the diagnosis and treatment of rosacea. 2010 Postgrad Med pmid:20107297
Li N et al. Effect of 1,4-cyclohexanediol on percutaneous absorption and penetration of azelaic acid. 2010 Int J Pharm pmid:20025951
Garelnabi M et al. Evaluation of a gas chromatography method for azelaic acid determination in selected biological samples. 2010 N Am J Med Sci pmid:22558586
Davis EC and Callender VD Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. 2010 J Clin Aesthet Dermatol pmid:20725554
Chae K et al. A multifaceted study of stigma/style cysteine-rich adhesin (SCA)-like Arabidopsis lipid transfer proteins (LTPs) suggests diversified roles for these LTPs in plant growth and reproduction. 2010 J. Exp. Bot. pmid:20667964
Verma P and Pathak K Therapeutic and cosmeceutical potential of ethosomes: An overview. 2010 J Adv Pharm Technol Res pmid:22247858
Xia Y et al. The glabra1 mutation affects cuticle formation and plant responses to microbes. 2010 Plant Physiol. pmid:20699396