Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Drug Eruptions D003875 30 associated lipids
Erythema D004890 22 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Rosacea D012393 13 associated lipids
Disease Resistance D060467 12 associated lipids
Hyperpigmentation D017495 11 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Keratosis D007642 9 associated lipids
Facial Dermatoses D005148 7 associated lipids
Alopecia Areata D000506 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Helfrich YR and Maier LM Topical and oral therapeutic approach to rosacea. 2016 Semin Cutan Med Surg pmid:27416312
Han S et al. Application of HPLC with ELSD detection for the assessment of azelaic acid impurities in liposomal formulation. 2013 ScientificWorldJournal pmid:24228008
Jung HW et al. Priming in systemic plant immunity. 2009 Science pmid:19342588
Parker JE The quest for long-distance signals in plant systemic immunity. 2009 Sci Signal pmid:19436056
Grosshans E and Chartier C [Therapeutic depigmentation agents]. 1987 Schweiz. Rundsch. Med. Prax. pmid:3671942
LaFranchi BW et al. Photoelectron resonance capture ionization mass spectrometry: a soft ionization source for mass spectrometry of particle-phase organic compounds. 2004 Rapid Commun. Mass Spectrom. pmid:15468105
Lanz C et al. Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm. 2009 Radiat. Res. pmid:19630524
Mingrone G et al. Influence of sodium salts of saturated medium chain length (C6, C9, C10 and C12) dicarboxylic acids on the uterine horn of rat in vitro. 1988 Q J Exp Physiol pmid:3164112
Elsaie ML and Choudhary S Updates on the pathophysiology and management of acne rosacea. 2009 Postgrad Med pmid:19820288
Scheinfeld N and Berk T A review of the diagnosis and treatment of rosacea. 2010 Postgrad Med pmid:20107297