| MeSH term | MeSH ID | Detail |
|---|---|---|
| Drug Eruptions | D003875 | 30 associated lipids |
| Erythema | D004890 | 22 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Disease Resistance | D060467 | 12 associated lipids |
| Hyperpigmentation | D017495 | 11 associated lipids |
| Dermatitis, Seborrheic | D012628 | 10 associated lipids |
| Keratosis | D007642 | 9 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Alopecia Areata | D000506 | 6 associated lipids |
Azelaic acid
Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
Cross Reference
Introduction
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azelaic acid?
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azelaic acid
PubChem Associated disorders and diseases
What pathways are associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azelaic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Azelaic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azelaic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Azelaic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azelaic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Azelaic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wolf JE et al. | Efficacy and safety of once-daily metronidazole 1% gel compared with twice-daily azelaic acid 15% gel in the treatment of rosacea. | 2006 | Cutis | pmid:16706244 |
| Worret WI and Fluhr JW | [Acne therapy with topical benzoyl peroxide, antibiotics and azelaic acid]. | 2006 | J Dtsch Dermatol Ges | pmid:16638058 |
| pmid:16631968 | ||||
| Del Rosso JQ | The use of topical azelaic acid for common skin disorders other than inflammatory rosacea. | 2006 | Cutis | pmid:16566285 |
| Bikowski JB | Case studies. | 2006 | Cutis | pmid:16566284 |
| Elewski B and Thiboutot D | A clinical overview of azelaic acid. | 2006 | Cutis | pmid:16566283 |
| Draelos ZD | The rationale for advancing the formulation of azelaic acid vehicles. | 2006 | Cutis | pmid:16566282 |
| Fleischer AB | The evolution of azelaic acid. | 2006 | Cutis | pmid:16566281 |
| Nally JB and Berson DS | Topical therapies for rosacea. | 2006 | J Drugs Dermatol | pmid:16468288 |
| Sasmaz S and Arican O | Comparison of azelaic acid and anthralin for the therapy of patchy alopecia areata: a pilot study. | 2005 | Am J Clin Dermatol | pmid:16343028 |
| Ziel K et al. | Cumulative irritation potential of metronidazole gel compared to azelaic acid gel after repeated applications to healthy skin. | 2005 Nov-Dec | J Drugs Dermatol | pmid:16302558 |
| Gollnick HP et al. | [Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies]. | 2004 | J Dtsch Dermatol Ges | pmid:16281587 |
| Fleischer A and Suephy C | The face and mind evaluation study: an examination of the efficacy of rosacea treatment using physician ratings and patients' self-reported quality of life. | 2005 Sep-Oct | J Drugs Dermatol | pmid:16167417 |
| Callender VD | Considerations for treating acne in ethnic skin. | 2005 | Cutis | pmid:16164153 |
| Roebuck HL | Face up to rosacea. | 2005 | Nurse Pract | pmid:16151303 |
| Punsalan T and Usatine RP | Red facial rash with "granitos". | 2005 | J Fam Pract | pmid:16144591 |
| Purdy S | Acne vulgaris. | 2005 | Clin Evid | pmid:16135322 |
| pmid:16133636 | ||||
| Kameyama K et al. | Treatment of reticulate acropigmentation of Kitamura with azelaic acid. An immunohistochemical and electron microscopic study. | 1992 | J. Am. Acad. Dermatol. | pmid:1613143 |
| Januszewski AS et al. | Lipid-derived modifications of plasma proteins in experimental and human diabetes. | 2005 | Ann. N. Y. Acad. Sci. | pmid:16037262 |
| pmid:16034895 | ||||
| Li H et al. | Prediction of genotoxicity of chemical compounds by statistical learning methods. | 2005 | Chem. Res. Toxicol. | pmid:15962942 |
| pmid:15857452 | ||||
| Page MM et al. | Ion chromatographic analysis of amines, alkanolamines, and associated anions in concrete. | 2005 | J Sep Sci | pmid:15835735 |
| van Zuuren EJ and Graber MA | The rigor of trials evaluating Rosacea treatments. | 2005 | Cutis | pmid:15810805 |
| Wolf JE | Present and future rosacea therapy. | 2005 | Cutis | pmid:15810803 |
| Januszewski AS et al. | Chemical modification of proteins during peroxidation of phospholipids. | 2005 | J. Lipid Res. | pmid:15805546 |
| Manosroi J et al. | Enhancement of the release of azelaic acid through the synthetic membranes by inclusion complex formation with hydroxypropyl-beta-cyclodextrin. | 2005 | Int J Pharm | pmid:15778061 |
| pmid:15724091 | ||||
| Kuster GM et al. | Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras. | 2005 | Circulation | pmid:15723974 |
| Marks R | Acne and its management beyond the age of 35 years. | 2004 | Am J Clin Dermatol | pmid:15663343 |
| Cayce KA et al. | Hyperpigmentation: an overview of the common afflictions. | 2004 | Dermatol Nurs | pmid:15624705 |
| Lindow KB | Rosacea. An overview of diagnosis and management. | 2004 | Adv Nurse Pract | pmid:15615217 |
| Shirokova E et al. | Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants. | 2005 | J. Biol. Chem. | pmid:15598656 |
| Draelos ZD | Noxious sensory perceptions in patients with mild to moderate rosacea treated with azelaic acid 15% gel. | 2004 | Cutis | pmid:15551720 |
| Czernielewski J and Liu Y | Comparison of 15% azelaic acid gel and 0.75% metronidazole gel for the topical treatment of papulopustular rosacea. | 2004 | Arch Dermatol | pmid:15492198 |
| Jansen T | Azelaic acid as a new treatment for perioral dermatitis: results from an open study. | 2004 | Br. J. Dermatol. | pmid:15491447 |
| LaFranchi BW et al. | Photoelectron resonance capture ionization mass spectrometry: a soft ionization source for mass spectrometry of particle-phase organic compounds. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15468105 |
| Halder RM and Richards GM | Topical agents used in the management of hyperpigmentation. | 2004 Jun-Jul | Skin Therapy Lett. | pmid:15334278 |
| Cetiner S et al. | Phototoxic effects of topical azelaic acid, benzoyl peroxide and adapalene were not detected when applied immediately before UVB to normal skin. | 2004 Jul-Aug | Eur J Dermatol | pmid:15319156 |
| Esposito E et al. | Ethosomes and liposomes as topical vehicles for azelaic acid: a preformulation study. | 2004 May-Jun | J Cosmet Sci | pmid:15264053 |
| Yoon TY et al. | A case of idiopathic eruptive macular pigmentation. | 2004 | J. Dermatol. | pmid:15187318 |
| pmid:15186195 | ||||
| Feldman S et al. | Diagnosis and treatment of acne. | 2004 | Am Fam Physician | pmid:15152959 |
| Azelaic acid, a new treatment for rosacea. | 2004 | Mayo Clin Womens Healthsource | pmid:15152174 | |
| pmid:15149246 | ||||
| pmid:15143009 | ||||
| Halder RM and Richards GM | Management of dyschromias in ethnic skin. | 2004 | Dermatol Ther | pmid:15113282 |
| Charnock C et al. | Evaluation of the antibacterial efficacy of diesters of azelaic acid. | 2004 | Eur J Pharm Sci | pmid:15066659 |
| Maple PA et al. | Comparison of the in-vitro activities of the topical antimicrobials azelaic acid, nitrofurazone, silver sulphadiazine and mupirocin against methicillin-resistant Staphylococcus aureus. | 1992 | J. Antimicrob. Chemother. | pmid:1506349 |