| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammation | D007249 | 119 associated lipids |
| Keratosis | D007642 | 9 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Melanosis | D008548 | 4 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Pituitary Apoplexy | D010899 | 1 associated lipids |
| Polycystic Ovary Syndrome | D011085 | 14 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Rhinophyma | D012224 | 1 associated lipids |
Azelaic acid
Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
Cross Reference
Introduction
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azelaic acid?
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azelaic acid
PubChem Associated disorders and diseases
What pathways are associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azelaic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azelaic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azelaic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azelaic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azelaic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Azelaic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gollnick H and Schramm M | Topical therapy in acne. | 1998 | J Eur Acad Dermatol Venereol | pmid:9891903 |
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| Spellman MC and Pincus SH | Efficacy and safety of azelaic acid and glycolic acid combination therapy compared with tretinoin therapy for acne. | 1998 Jul-Aug | Clin Ther | pmid:9737831 |
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| Rodriguez-Vicente J et al. | The effects of different antineoplastic agents and of pretreatment by modulators on three melanoma lines. | 1998 | Cancer | pmid:9452267 |
| Gibson JR | Azelaic acid 20% cream (AZELEX) and the medical management of acne vulgaris. | 1997 | Dermatol Nurs | pmid:9392765 |
| Parsons PG et al. | Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells. | 1997 | Biochem. Pharmacol. | pmid:9264325 |
| Jansen T and Plewig G | Advances and perspectives in acne therapy. | 1997 | Eur. J. Med. Res. | pmid:9262484 |
| Rodriguez-Vicente J et al. | Azelaic acid was sensitizing effect in the chemotherapeutic treatment of several melanoma cell lines. | 1996 | Pigment Cell Res. | pmid:9125756 |
| Mackrides PS and Shaughnessy AF | Azelaic acid therapy for acne. | 1996 | Am Fam Physician | pmid:8961845 |
| Nazzaro-Porro M et al. | A case of recurrent (following surgery x2) invasive malignant melanoma with satellitosis (stage IIIA) successfully resolving after azelaic acid treatment administered by several routes. | 1996 | Clin. Exp. Dermatol. | pmid:8959915 |
| Oh CW and Myung KB | An ultrastructural study of the retention hyperkeratosis of experimentally induced comedones in rabbits: the effects of three comedolytics. | 1996 | J. Dermatol. | pmid:8935627 |
| Lowe NJ | New approaches in dermatology: a clinical profile of azelaic acid. | 1996 | Cutis | pmid:8654130 |
| Breathnach AS | Melanin hyperpigmentation of skin: melasma, topical treatment with azelaic acid, and other therapies. | 1996 | Cutis | pmid:8654129 |
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| Gibson JR | Rationale for the development of new topical treatments for acne vulgaris. | 1996 | Cutis | pmid:8654127 |
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| Addo-Boadu K et al. | Azelaic acid decreases the fibrinolytic potential of cultured human melanoma cells in vitro. | 1996 | Cancer Lett. | pmid:8635147 |
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| Azelaic acid--a new topical treatment for acne. | 1993 | Drug Ther Bull | pmid:8344141 | |
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