Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Crea F et al. Sequestering ability of polycarboxylic ligands towards dioxouranium(VI). 2008 Talanta pmid:18585146
Gollnick H and Layton A Azelaic acid 15% gel in the treatment of rosacea. 2008 Expert Opin Pharmacother pmid:18803456
Herkenne C et al. In vivo methods for the assessment of topical drug bioavailability. 2008 Pharm. Res. pmid:17985216
Arizaga GG et al. Chemical modification of zinc hydroxide nitrate and Zn-Al-layered double hydroxide with dicarboxylic acids. 2008 J Colloid Interface Sci pmid:18243238
Thiboutot DM et al. Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea. 2008 J Drugs Dermatol pmid:18561584
Iraji F et al. Efficacy of topical azelaic acid gel in the treatment of mild-moderate acne vulgaris. 2007 Mar-Apr Indian J Dermatol Venereol Leprol pmid:17456913
Hinz DC Efficiency improvement for sulfated ash determination by usage of a microwave muffle furnace. 2007 J Pharm Biomed Anal pmid:17280812
Manosroi A et al. Characteristics and anti-proliferative activity of azelaic acid and its derivatives entrapped in bilayer vesicles in cancer cell lines. 2007 J Drug Target pmid:17541842
Satoh M et al. Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen. 2007 Circulation pmid:17562954
Colón LE et al. Cumulative irritation potential among metronidazole gel 1%, metronidazole gel 0.75%, and azelaic acid gel 15%. 2007 Cutis pmid:17500380