Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Reis CP et al. Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. 2013 Microsc. Microanal. pmid:23673203
Breathnach AS Azelaic acid: potential as a general antitumoural agent. 1999 Med. Hypotheses pmid:10362281
Gollnick H [Azelaic acid for keratinization disorders?]. 1991 Med Monatsschr Pharm pmid:1838401
Azelaic acid (Finacea) for rosacea. 2003 Med Lett Drugs Ther pmid:12968125
Azelaic acid-a new topical drug for acne. 1996 Med Lett Drugs Ther pmid:8637482
Piquero Martín J et al. [Double-blind clinical study of the treatment of melasma with azelaic acid versus hydroquinone]. 1988 Med Cutan Ibero Lat Am pmid:3073279
Azelaic acid, a new treatment for rosacea. 2004 Mayo Clin Womens Healthsource pmid:15152174
Nazzaro-Porro M et al. Effect of azelaic acid on human malignant melanoma. 1980 Lancet pmid:6103442
Tacchino RM et al. Short-term infusion of azelaic acid vs intralipid in healthy subjects evaluated by indirect calorimetry. 1990 Mar-Apr JPEN J Parenter Enteral Nutr pmid:2112625
Mingrone G et al. Preliminary studies of a dicarboxylic acid as an energy substrate in man. 1989 May-Jun JPEN J Parenter Enteral Nutr pmid:2503641