Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Yu JS and Kim AK Effect of combination of taurine and azelaic acid on antimelanogenesis in murine melanoma cells. 2010 J. Biomed. Sci. pmid:20804622
Iraji F et al. Efficacy of 15% azelaic acid in psoriasis vulgaris: a randomized, controlled clinical trial. 2010 J Drugs Dermatol pmid:20684146
Choi YS et al. A study of the efficacy of cleansers for acne vulgaris. 2010 J Dermatolog Treat pmid:20394494
Pazoki-Toroudi H et al. Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. 2010 J Dermatolog Treat pmid:20394495
Fluhr JW and Degitz K [Antibiotics, azelaic acid and benzoyl peroxide in topical acne therapy]. 2010 J Dtsch Dermatol Ges pmid:20482689
Del Rosso JQ et al. Efficacy of topical azelaic acid (AzA) gel 15% plus oral doxycycline 40 mg versus metronidazole gel 1% plus oral doxycycline 40 mg in mild-to-moderate papulopustular rosacea. 2010 J Drugs Dermatol pmid:20645521
Preisz K and Kárpáti S [Rosacea: pathogenesis, clinical forms and therapy]. 2010 Orv Hetil pmid:20650811
Hoye TR et al. Total synthesis of peloruside A through kinetic lactonization and relay ring-closing metathesis cyclization reactions. 2010 Angew. Chem. Int. Ed. Engl. pmid:20645374
Sun H et al. Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509). 2010 Stand Genomic Sci pmid:21304737
Litvinov D et al. Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. 2010 Atherosclerosis pmid:19880116