Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Thiboutot D et al. Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: results from two vehicle-controlled, randomized phase III studies. 2003 J. Am. Acad. Dermatol. pmid:12789172
Webster G Combination azelaic acid therapy for acne vulgaris. 2000 J. Am. Acad. Dermatol. pmid:10898830
Sheth VM and Pandya AG Melasma: a comprehensive update: part II. 2011 J. Am. Acad. Dermatol. pmid:21920242
Elewski BE et al. In reference to the October 2004 comprehensive overview of rosacea therapy. 2007 J. Am. Acad. Dermatol. pmid:17870440
Kameyama K et al. Treatment of reticulate acropigmentation of Kitamura with azelaic acid. An immunohistochemical and electron microscopic study. 1992 J. Am. Acad. Dermatol. pmid:1613143
Gupta AK et al. The treatment of melasma: a review of clinical trials. 2006 J. Am. Acad. Dermatol. pmid:17097400
van Zuuren EJ et al. Systematic review of rosacea treatments. 2007 J. Am. Acad. Dermatol. pmid:17190628
Nazzaro-Porro M Azelaic acid. 1987 J. Am. Acad. Dermatol. pmid:2963038
Coda AB et al. Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel. 2013 J. Am. Acad. Dermatol. pmid:23871720
Wu YH et al. Effects of Chinese herbal medicine combined with He-Ne laser on lipoperoxide and superoxide dismutase in chloasma patients. 2009 J Tradit Chin Med pmid:19894376