Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

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Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Parodi A et al. Treatment of rosacea. 2011 Ann Dermatol Venereol pmid:22183101
Parodi A et al. [Treatment of rosacea]. 2011 Ann Dermatol Venereol pmid:21907876
Ortonne JP [Depigmenting chemical agents]. 1986 Ann Dermatol Venereol pmid:3800227
Januszewski AS et al. Lipid-derived modifications of plasma proteins in experimental and human diabetes. 2005 Ann. N. Y. Acad. Sci. pmid:16037262
Zaffaroni N et al. Cytotoxic activity of azelaic acid against human melanoma primary cultures and established cell lines. 1990 Nov-Dec Anticancer Res. pmid:2285231
Száraz I and Forsling W Interaction between a capacitor electrolyte and gamma-aluminum oxide studied by Fourier transform infrared spectroscopy. 2003 Appl Spectrosc pmid:14658693
Czernielewski J and Liu Y Comparison of 15% azelaic acid gel and 0.75% metronidazole gel for the topical treatment of papulopustular rosacea. 2004 Arch Dermatol pmid:15492198
Liu RH et al. Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. 2006 Arch Dermatol pmid:16924055
Wilkerson MG and Wilkin JK Azelaic acid esters do not depigment pigmented guinea pig skin. 1990 Arch Dermatol pmid:2301969
Grimes PE Melasma. Etiologic and therapeutic considerations. 1995 Arch Dermatol pmid:7492140