| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
Azelaic acid
Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
Cross Reference
Introduction
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azelaic acid?
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azelaic acid
PubChem Associated disorders and diseases
What pathways are associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azelaic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azelaic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azelaic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azelaic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azelaic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Azelaic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nazzaro-Porro M et al. | The depigmenting effect of azelaic acid. | 1990 | Arch Dermatol | pmid:2073286 |
| Liu RH et al. | Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. | 2006 | Arch Dermatol | pmid:16924055 |
| Thiboutot D | New treatments and therapeutic strategies for acne. | 2000 | Arch Fam Med | pmid:10693736 |
| Akman A et al. | Treatment of acne with intermittent and conventional isotretinoin: a randomized, controlled multicenter study. | 2007 | Arch. Dermatol. Res. | pmid:17710426 |
| Schallreuter KU and Wood JW | A possible mechanism of action for azelaic acid in the human epidermis. | 1990 | Arch. Dermatol. Res. | pmid:2114832 |
| Akamatsu H et al. | Inhibitory effect of azelaic acid on neutrophil functions: a possible cause for its efficacy in treating pathogenetically unrelated diseases. | 1991 | Arch. Dermatol. Res. | pmid:1867478 |
| Litvinov D et al. | Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice. | 2010 | Atherosclerosis | pmid:19880116 |
| Goodman G | Managing acne vulgaris effectively. | 2006 | Aust Fam Physician | pmid:16969442 |
| Auld J | Topical therapy of acne. | 1986 | Australas. J. Dermatol. | pmid:2957990 |
| Brinkworth RI et al. | Inhibition of HIV-1 proteinase by non-peptide carboxylates. | 1991 | Biochem. Biophys. Res. Commun. | pmid:2018518 |