Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Rosacea D012393 13 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperpigmentation D017495 11 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Disease Resistance D060467 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Zina G [Azelaic acid: an innovation in the treatment of acne. Introduction and history]. 1989 G Ital Dermatol Venereol pmid:2534549
Breathnach AS et al. Effect of dicarboxylic acids (C6 and C9) on human choroidal melanoma in cell culture. 1989 Invest. Ophthalmol. Vis. Sci. pmid:2925320
Verallo-Rowell VM et al. Double-blind comparison of azelaic acid and hydroquinone in the treatment of melasma. 1989 Acta Derm Venereol Suppl (Stockh) pmid:2528260
Nazzaro-Porro M et al. [Azelaic acid in the treatment of acne]. 1989 G Ital Dermatol Venereol pmid:2530163
Azelaic acid: a new therapeutic agent. Proceedings of the CMD-satellite-symposium on azelaic acid. 17th World Congress of Dermatology. Berlin, May 1987. 1989 Acta Derm Venereol Suppl (Stockh) pmid:2773613
Nazzaro-Porro M et al. Ten years' experience of treating lentigo maligna with topical azelaic acid. 1989 Acta Derm Venereol Suppl (Stockh) pmid:2773614
Nüssgen AI et al. Topographical analysis of proliferation ([3H]thymidine labelling index and mitotic index) as compared with tumour growth and tumour weight in xenotransplanted melanoma. Changes due to local and systemic application of azelaic acid. 1989 Acta Derm Venereol Suppl (Stockh) pmid:2773615
Flamigni F et al. Involvement of thiol transferase- and thioredoxin-dependent systems in the protection of 'essential' thiol groups of ornithine decarboxylase. 1989 Biochem. J. pmid:2719637
Landthaler M et al. [Lentigo of the glans penis]. 1989 Hautarzt pmid:2732050
Jorand JP et al. The "survival hormones": azelaic and pimelic acids, suppress the stress elicited by isolation conditions on the steroids and phospholipids of adult worker honeybees. 1989 Horm. Metab. Res. pmid:2807145