| MeSH term | MeSH ID | Detail |
|---|---|---|
| Rosacea | D012393 | 13 associated lipids |
| Dermatitis, Seborrheic | D012628 | 10 associated lipids |
| Hyperpigmentation | D017495 | 11 associated lipids |
| Hutchinson's Melanotic Freckle | D018327 | 2 associated lipids |
| Dermatitis, Perioral | D019557 | 4 associated lipids |
| Pituitary ACTH Hypersecretion | D047748 | 1 associated lipids |
| Disease Resistance | D060467 | 12 associated lipids |
Azelaic acid
Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.
Cross Reference
Introduction
To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azelaic acid?
Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azelaic acid
PubChem Associated disorders and diseases
What pathways are associated with Azelaic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azelaic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azelaic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azelaic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azelaic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azelaic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Azelaic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Flamigni F et al. | Involvement of thiol transferase- and thioredoxin-dependent systems in the protection of 'essential' thiol groups of ornithine decarboxylase. | 1989 | Biochem. J. | pmid:2719637 |
| Picardo M et al. | Activity of azelaic acid on cultures of lymphoma- and leukemia-derived cell lines, normal resting and stimulated lymphocytes and 3T3 fibroblasts. | 1985 | Biochem. Pharmacol. | pmid:4004885 |
| Parsons PG et al. | Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells. | 1997 | Biochem. Pharmacol. | pmid:9264325 |
| Muthulakshmi S and Saravanan R | Efficacy of azelaic acid on hepatic key enzymes of carbohydrate metabolism in high fat diet induced type 2 diabetic mice. | 2013 | Biochimie | pmid:23402910 |
| Dousset N and Douste-Blazy L | [Azelaic acid transformation into monocarboxylic fatty acids in vivo in the rat]. | 1973 | Biochimie | pmid:4793585 |
| Devereux M et al. | Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine). | 2006 | Bioinorg Chem Appl | pmid:17497019 |
| Banerjee S et al. | Proxyl nitroxide of lithocholic acid: a potential spin probe for model membranes. | 1993 | Bioorg. Med. Chem. | pmid:8081864 |
| Gutheil WG | Application of hierarchical thermodynamic interactions to the protonation equilibria of organic polyprotic acids. | 2000 | Biophys. Chem. | pmid:11152269 |
| Sato C et al. | Cellulase applied to the leaves of sweet pepper (Capsicum annuum L. var. grossum) upregulates the production of salicylic and azelaic acids. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21512237 |
| Champigny MJ et al. | Localization of DIR1 at the tissue, cellular and subcellular levels during Systemic Acquired Resistance in Arabidopsis using DIR1:GUS and DIR1:EGFP reporters. | 2011 | BMC Plant Biol. | pmid:21896186 |