Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Rosacea D012393 13 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperpigmentation D017495 11 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Disease Resistance D060467 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
Fleischer A and Suephy C The face and mind evaluation study: an examination of the efficacy of rosacea treatment using physician ratings and patients' self-reported quality of life. 2005 Sep-Oct J Drugs Dermatol pmid:16167417
Ziel K et al. Cumulative irritation potential of metronidazole gel compared to azelaic acid gel after repeated applications to healthy skin. 2005 Nov-Dec J Drugs Dermatol pmid:16302558
Li H et al. Prediction of genotoxicity of chemical compounds by statistical learning methods. 2005 Chem. Res. Toxicol. pmid:15962942
Page MM et al. Ion chromatographic analysis of amines, alkanolamines, and associated anions in concrete. 2005 J Sep Sci pmid:15835735
Januszewski AS et al. Chemical modification of proteins during peroxidation of phospholipids. 2005 J. Lipid Res. pmid:15805546
Manosroi J et al. Enhancement of the release of azelaic acid through the synthetic membranes by inclusion complex formation with hydroxypropyl-beta-cyclodextrin. 2005 Int J Pharm pmid:15778061
Kuster GM et al. Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras. 2005 Circulation pmid:15723974
Callender VD Considerations for treating acne in ethnic skin. 2005 Cutis pmid:16164153
Januszewski AS et al. Lipid-derived modifications of plasma proteins in experimental and human diabetes. 2005 Ann. N. Y. Acad. Sci. pmid:16037262
Hung HM et al. Products and mechanisms of the reaction of oleic acid with ozone and nitrate radical. 2005 J Phys Chem A pmid:16833788