Azelaic acid

Azelaic acid is a lipid of Fatty Acyls (FA) class. Azelaic acid is associated with abnormalities such as Bacterial Infections and Infection. The involved functions are known as Anabolism, Signal Transduction, Plant Immunity, Signal and Signal Transduction Pathways. Azelaic acid often locates in Body tissue. The associated genes with Azelaic acid are AZI1 gene, FKBPL gene and MLL gene. The related lipids are sebacic acid.

Cross Reference

Introduction

To understand associated biological information of Azelaic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azelaic acid?

Azelaic acid is suspected in Infection, Bacterial Infections and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azelaic acid

MeSH term MeSH ID Detail
Rosacea D012393 13 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperpigmentation D017495 11 associated lipids
Hutchinson's Melanotic Freckle D018327 2 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Pituitary ACTH Hypersecretion D047748 1 associated lipids
Disease Resistance D060467 12 associated lipids
Per page 10 20 50 | Total 27

PubChem Associated disorders and diseases

What pathways are associated with Azelaic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Azelaic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azelaic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azelaic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azelaic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azelaic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azelaic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Azelaic acid

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Authors Title Published Journal PubMed Link
pmid:17927163
pmid:17931096
Herkenne C et al. In vivo methods for the assessment of topical drug bioavailability. 2008 Pharm. Res. pmid:17985216
pmid:18045355
Baliña LM and Graupe K The treatment of melasma. 20% azelaic acid versus 4% hydroquinone cream. 1991 Int. J. Dermatol. pmid:1816137
Maher HK Rosacea. 2007 AAOHN J pmid:18183803
Arizaga GG et al. Chemical modification of zinc hydroxide nitrate and Zn-Al-layered double hydroxide with dicarboxylic acids. 2008 J Colloid Interface Sci pmid:18243238
Thiboutot D Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris. 2008 J Drugs Dermatol pmid:18246693
Chen Z et al. Versatile synthesis strategy for carboxylic acid-functionalized upconverting nanophosphors as biological labels. 2008 J. Am. Chem. Soc. pmid:18278910
pmid:18280490
Kanitakis J Linea fusca in a male adolescent successfully treated with azelaic acid. 2008 J Eur Acad Dermatol Venereol pmid:18331308
pmid:18377339
Gollnick H [Azelaic acid for keratinization disorders?]. 1991 Med Monatsschr Pharm pmid:1838401
pmid:18394082
De Filippis D et al. Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats. 2009 J. Cell. Mol. Med. pmid:18429935
Stewart JJ Application of the PM6 method to modeling the solid state. 2008 J Mol Model pmid:18449579
Piskin S and Uzunali E A review of the use of adapalene for the treatment of acne vulgaris. 2007 Ther Clin Risk Manag pmid:18472984
pmid:18535811
Thiboutot DM et al. Azelaic acid 15% gel once daily versus twice daily in papulopustular rosacea. 2008 J Drugs Dermatol pmid:18561584
Crea F et al. Sequestering ability of polycarboxylic ligands towards dioxouranium(VI). 2008 Talanta pmid:18585146
pmid:18641447
Akamatsu H et al. Inhibitory effect of azelaic acid on neutrophil functions: a possible cause for its efficacy in treating pathogenetically unrelated diseases. 1991 Arch. Dermatol. Res. pmid:1867478
Mostafa FF et al. Comparative study of some treatment modalities of rosacea. 2009 J Eur Acad Dermatol Venereol pmid:18705632
pmid:18728922
Rup S et al. The ultrasound-assisted oxidative scission of monoenic fatty acids by ruthenium tetroxide catalysis: influence of the mixture of solvents. 2009 Ultrason Sonochem pmid:18799341
Gollnick H and Layton A Azelaic acid 15% gel in the treatment of rosacea. 2008 Expert Opin Pharmacother pmid:18803456
Lee GS Intravenous vitamin C in the treatment of post-laser hyperpigmentation for melasma: a short report. 2008 J Cosmet Laser Ther pmid:18830869
pmid:19022456
pmid:19055345
Bertuzzi A et al. Pharmacokinetic analysis of azelaic acid disodium salt. A proposed substrate for total parenteral nutrition. 1991 Clin Pharmacokinet pmid:1908756
pmid:19126734
pmid:19160531
Melnik BC et al. Anti-acne agents attenuate FGFR2 signal transduction in acne. 2009 J. Invest. Dermatol. pmid:19225542
Gooderham M Rosacea and its topical management. 2009 Skin Therapy Lett. pmid:19330270
Jung HW et al. Priming in systemic plant immunity. 2009 Science pmid:19342588
Del Rosso JQ et al. Impact of order of application of moisturizers on percutaneous absorption kinetics: evaluation of sequential application of moisturizer lotions and azelaic acid gel 15% using a human skin model. 2009 Cutis pmid:19363903
pmid:19433342
Parker JE The quest for long-distance signals in plant systemic immunity. 2009 Sci Signal pmid:19436056
Purdy S and Deberker D Acne vulgaris. 2008 BMJ Clin Evid pmid:19450306
pmid:19465852
Bowler PJ Impact on facial rejuvenation with dermatological preparations. 2009 Clin Interv Aging pmid:19503770
Korting HC and Schöllmann C Current topical and systemic approaches to treatment of rosacea. 2009 J Eur Acad Dermatol Venereol pmid:19508315
Culp B and Scheinfeld N Rosacea: a review. 2009 P T pmid:19562004
Thiboutot DM et al. A multicenter study of topical azelaic acid 15% gel in combination with oral doxycycline as initial therapy and azelaic acid 15% gel as maintenance monotherapy. 2009 J Drugs Dermatol pmid:19588640
pmid:19608057
Shah J Plants under attack: systemic signals in defence. 2009 Curr. Opin. Plant Biol. pmid:19608451
Lanz C et al. Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm. 2009 Radiat. Res. pmid:19630524
pmid:19643540
Goldgar C et al. Treatment options for acne rosacea. 2009 Am Fam Physician pmid:19725487
Que SK and Bergstrom KG Hyperpigmentation: old problem, new therapies. 2009 J Drugs Dermatol pmid:19746682